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Protein Overview: Sp7-PD

General Information:
Name(s) found: Sp7-PD / FBpp0081240 [FlyBase]
Description(s) found:
Found 14 descriptions.
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  • The gene Serine protease 7 is referred to in FlyBase by the symbol Dmel\Sp7 (CG3066, FBgn0037515). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:3585508..3589154. It has the cytological map location 84D14-84E1. Based on sequence similarity, it is predicted to have molecular function</span>: serine-type endopeptidase activity. There is experimental evidence that it is involved in the biological process</span>: melanization defense response; positive regulation of melanization defense response. 9 alleles are reported. No phenotypic data is available. It has 4 annotated transcripts and 4 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 169 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: proteolysis [IEA][NAS]
    positive regulation of melanization defense response [IMP]
    defense response [NAS]
    melanization defense response [IMP][NAS]
    Molecular Function: serine-type endopeptidase activity [IEA][ISS][NAS]
    serine-type peptidase activity [NAS]
    serine-type carboxypeptidase activity [NAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKSTRKVVGI FLATCLLPFT VLQNVAAQGS CRNPNQKQGQ CLSIYDCQSL LSVIQQSYVS  60
   61 PEDRTFLRNS QCLDGVGRQP YVCCTSDRSF GSQEATSAAP PPTTTSSSSR GQDGQAGLGN 120
  121 LLPSPPKCGP HSFSNKVYNG NDTAIDEFNW MALLEYVDRD GGNSVAVAV

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..169] PSI-BLAST 3.221849 Crystal structure of prophenoloxidase activating factor-II from the beetle Holotrichia diomphalia


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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