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Protein Overview: CG1090-PB

General Information:
Name(s) found: CG1090-PB / FBpp0078552 [FlyBase]
Description(s) found:
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  • gi|45550690|ref|NP_649459.3| CG1090, isoform B [Drosophila melanogaster] [NCBI NR]
  • gi|45446376|gb|AAN13306.3| CG1090, isoform B [Drosophila melanogaster] [NCBI NR]
  • gi|134034178|sp|Q9VN12.3|NCKXH_DROME RecName: Full=Probable sodium/potassium/calcium exchanger CG1090; AltName: Full=Na(+)/K(+)/Ca(2+)-exchange protein CG1090 [NCBI NR]
  • Probable sodium/potassium/calcium exchanger CG1090 OS=Drosophila melanogaster GN=CG1090 PE=2 SV=3 [Swiss-Prot]
  • This gene is referred to in FlyBase by the symbol Dmel\CG1090 (CG1090, FBgn0037238). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:185510..192577. It has the cytological map location 82A4. Based on sequence similarity, it is predicted to have molecular function</span>: calcium, potassium:sodium antiporter activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: calcium ion transport; sodium ion transport. 9 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
  • (AAN13306) CG1090-PB [DrosMelano7227.FASTAC.txt]
  • CG1090-PB, isoform B [Drosophila melanogaster]gi|45550690|ref|NP_649459.3| CG1090-PB [Drosophila melanogaster] [nrdb_11152004_Chlamydomonas]
  • type=protein; loc=3R:join(186007..186009,189000..189230,189284..189518,189939..190228,190288..191263,191424..191617); ID=FBpp0078552; name=CG1090-PB; parent=FBgn0037238,FBtr0078912; dbxref=GB_protein:AAN13306.2,FlyBase:FBpp0078552,FlyBase_Annotation_IDs:C [fly-100309-contam.fasta]
  • CG1090-PB, isoform B [Drosophila melanogaster] [nr-271106-contam.fasta]
  • type=protein; loc=3R:join(186007..186009,189000..189230,189284..189518,189939..190228,190288..191263,191424..191617); ID=FBpp0078552; name=CG1090-PB; parent=FBgn0037238,FBtr0078912; dbxref=GB_protein:AAN13306.2,FlyBase:FBpp0078552,FlyBase_Annotation_IDs:CG1090-PB,GB_protein:AAN13306.3,REFSEQ:NP_649459,GB_protein:AAN13306; MD5=f6f7a0ae4335f9745385c737311fb22c; length=642; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta]
  • type=protein; loc=3R:join(186007..186009,189000..189230,189284..189518,189939..190228,190288..191263,191424..191617); ID=FBpp0078552; name=CG1090-PB; parent=FBgn0037238,FBtr0078912; dbxref=GB_protein:AAN13306.2,FlyBase:FBpp0078552,FlyBase_Annotation_IDs:CG1090-PB,GB_protein:AAN13306.3,REFSEQ:NP_649459,GB_protein:AAN13306; MD5=f6f7a0ae4335f9745385c737311fb22c; length=642; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta]
    • Organism: Drosophila melanogaster
    Length: 642 amino acids

    Gene Ontology:
    Cellular Component: integral to membrane [ISS]
    Biological Process: sodium ion transport [ISS]
    transmembrane transport [IEA]
    calcium ion transport [ISS]
    Molecular Function: calcium, potassium:sodium antiporter activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIVRSRSRRA RMWNMGLLFL IYYCVSIYSA KGDTKDGQVL PLDVGALAED AGDAEANGED  60
   61 TPERNSESSV LDTTLAFEPQ ASTQSTPIHG AVPTWRPKRD NCTPPAIEQF PQPLMNKWAR 120
  121 QHGGLILHIL VAVFTFFGLA IVCDEYFVAS LDRLCEELKL SPDVAGATFM AAGSSAPELA 180
  181 TVVIGVFFAK DDIGISGVIG SAVFNIMFVI SVCALCSGTV CQLNWWPLVR DCFFYCVSIL 240
  241 VMLIIIFNDV ISCFESVVML LCYVGYCVAL HFNTELERWA LGLNLPFKLP SKEEQSALVT 300
  301 YKNVPEGSYT QESVGQTQGQ KATDDSETRS AKPQSDYQDY SDPNPTWDPN AAWGDESQPN 360
  361 PVANPPPVDD WGMGHSGQEN MGYHADQPES VVTGDGPPAA VKSGGQVVST QATSAGGNDY 420
  421 YKSTDKQREP RRDPLLRPME GGLPALVSWY VVYPIHFLCK KTMPDCRQEQ YRNWYPFTFL 480
  481 MSMVWISFYS YFMVWMITVI GSTLAIPDTV MGLTFVAAGV SVPDALSSIA VIKEGFGDMA 540
  541 VSNAIGSNVF DILVCLGLPW FIQTAIIKPG SHVNVISKGL AYSTLSLFST VVFLILSTHL 600
  601 NGWKLDKRLG IILMVWYLFF ITLASLYELN VFGYMNPPEC PS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..284] Pfam 34.79588 No description for PF01699.15 was found. No confident structure predictions are available.
    2 View Details [285..439] deduced N/A No confident structure predictions are available.
    3 View Details [440..642] Pfam 38.267606 No description for PF01699.15 was found. No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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