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Protein Overview: FOXK2

General Information:
Name(s) found: FOXK2 [HGNC (HUGO)]
Description(s) found:
Found 27 descriptions.
SHOW ALL
  • forkhead box K2 [HGNC (HUGO)]
    • Organism: Homo sapiens
    Length: 660 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAAAAAALSG AGTPPAGGGA GGGGAGGGGS PPGGWAVARL EGREFEYLMK KRSVTIGRNS  60
   61 SQGSVDVSMG HSSFISRRHL EIFTPPGGGG HGGAAPELPP AQPRPDAGGD FYLRCLGKNG 120
  121 VFVDGVFQRR GAPPLQLPRV CTFRFPSTNI KITFTALSSE KREKQEASES PVKAVQPHIS 180
  181 PLTINIPDTM AHLISPLPSP TGTISAANSC PSSPRGAGSS GYKVGRVMPS DLNLMADNSQ 240
  241 PENEKEASGG DSPKDDSKPP YSYAQLIVQA ITMAPDKQLT LNGIYTHITK NYPYYRTADK 300
  301 GWQNSIRHNL SLNRYFIKVP RSQEEPGKGS FWRIDPASES KLIEQAFRKR RPRGVPCFRT 360
  361 PLGPLSSRSA PASPNHAGVL SAHSSGAQTP ESLSREGSPA PLEPEPGAAQ PKLAVIQEAR 420
  421 FAQSAPGSPL SSQPVLITVQ RQLPQAIKPV TYTVATPVTT STSQPPVVQT VHVVHQIPAV 480
  481 SVTSVAGLAP ANTYTVSGQA VVTPAAVLAP PKAEAQENGD HREVKVKVEP IPAIGHATLG 540
  541 TASRIIQTAQ TTPVQTVTIV QQAPLGQHQL PIKTVTQNGT HVASVPTAVH GQVNNAAASP 600
  601 LHMLATHASA SASLPTKRHN GDQPEQPELK RIKTEDGEGI VIALSVDTPP AAVREKGVQN 660
  661

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..241] FFAS03 2.05 Phosphotyrosine binding domain of Rad53
    2 View Details [242..358] PSI-BLAST 18.221849 No description for 2c6yA was found.
    3 View Details [359..544] deduced N/A No confident structure predictions are available.
    4 View Details [545..660] MSA 4.207986 View MSA. Confident ab initio structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • binding
    		•  3.49130250684713 bayes_pls_golite062009
  • transcription regulator activity
    		•  3.38780975952028 bayes_pls_golite062009
  • DNA binding
    		•  3.17754626214699 bayes_pls_golite062009
  • nucleic acid binding
    		•  3.1171915055278 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  2.41431149922235 bayes_pls_golite062009
  • protein binding
    		•  2.20369144716037 bayes_pls_golite062009
  • transcription factor activity
    		•  2.00503872581265 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  1.58636372907213 bayes_pls_golite062009
  • transforming growth factor beta receptor, cytoplasmic mediator activity
    		•  1.48263552027263 bayes_pls_golite062009
  • transcription activator activity
    		•  1.45614128243985 bayes_pls_golite062009
  • transmembrane receptor protein serine/threonine kinase signaling protein activity
    		•  1.2840212954552 bayes_pls_golite062009
  • chromatin binding
    		•  1.24734533820287 bayes_pls_golite062009
  • promoter binding
    		•  1.19827477319554 bayes_pls_golite062009
  • transcription factor binding
    		•  0.840886266060694 bayes_pls_golite062009
  • transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity
    		•  0.829235284155381 bayes_pls_golite062009
  • receptor signaling protein activity
    		•  0.196567610974905 bayes_pls_golite062009
  • transcription repressor activity
    		•  0.0741267027726338 bayes_pls_golite062009
    2
    Term Confidence Notes
  • transcription regulator activity
    		•  5.55329976718261 bayes_pls_golite062009
  • DNA binding
    		•  5.08959163553491 bayes_pls_golite062009
  • nucleic acid binding
    		•  4.99681957904233 bayes_pls_golite062009
  • transcription factor activity
    		•  4.33152142980289 bayes_pls_golite062009
  • binding
    		•  3.52874320222492 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  2.60738445921725 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  2.48053910222825 bayes_pls_golite062009
  • transcription activator activity
    		•  2.37668609508629 bayes_pls_golite062009
  • transcription repressor activity
    		•  2.22485867684613 bayes_pls_golite062009
  • transcription factor binding
    		•  0.85714789329232 bayes_pls_golite062009
  • protein binding
    		•  0.753698599635855 bayes_pls_golite062009
  • specific RNA polymerase II transcription factor activity
    		•  0.66743181561551 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity, enhancer binding
    		•  0.23177057841536 bayes_pls_golite062009
    3 No functions predicted.
    4 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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