Protein Overview: toc-PF

General Information:
Name(s) found:	toc-PF / FBpp0111796 [FlyBase]
Description(s) found: SHOW ONLY BEST	gi\|161076652\|ref\|NP_001097064.1\| toucan, isoform F [Drosophila melanogaster] [NCBI NR] gi\|157400051\|gb\|ABV53609.1\| toucan, isoform F [Drosophila melanogaster] [NCBI NR] The gene toucan is referred to in FlyBase by the symbol Dmel\toc (CG9660, FBgn0015600). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:3068339..3144613. It has the cytological map location 23D1-23D2. It is reported to have molecular function</span>: protein kinase binding. There is experimental evidence that it is involved in the biological process</span>: syncytial blastoderm mitotic cell cycle. 33 alleles are reported. The phenotypes of these alleles are annotated with 12 unique terms, many of which group under: female germline cyst; organ system; spindle; intracellular organelle part; anatomical structure; egg; protein complex; spindle microtubule; cytoskeletal part; germarium; nuclear part. It has 6 annotated transcripts and 6 annotated polypeptides. [FlyBase] type=protein; loc=2L:complement(3069714..3070731,3070823..3071504,3071569..3071764,3072156..3072308); ID=FBpp0111796; name=toc-PF; parent=FBgn0015600,FBtr0112883; dbxref=FlyBase:FBpp0111796,FlyBase_Annotation_IDs:CG9660-PF,REFSEQ:NP_001097064,GB_protein:A [fly-100309-contam.fasta] type=protein; loc=2L:complement(3069714..3070731,3070823..3071504,3071569..3071764,3072156..3072308); ID=FBpp0111796; name=toc-PF; parent=FBgn0015600,FBtr0112883; dbxref=FlyBase:FBpp0111796,FlyBase_Annotation_IDs:CG9660-PF,REFSEQ:NP_001097064,GB_protein:ABV53609; MD5=732b0d6869d55fa0dc0024cf074050e6; length=682; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta] type=protein; loc=2L:complement(3069714..3070731,3070823..3071504,3071569..3071764,3072156..3072308); ID=FBpp0111796; name=toc-PF; parent=FBgn0015600,FBtr0112883; dbxref=FlyBase:FBpp0111796,FlyBase_Annotation_IDs:CG9660-PF,REFSEQ:NP_001097064,GB_protein:ABV53609; MD5=732b0d6869d55fa0dc0024cf074050e6; length=682; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta] Toucan, isoform F OS=Drosophila melanogaster GN=toc PE=4 SV=1 [UniProt_drosophila_07-01-2011_reversed.fasta] type=protein; loc=2L:complement(3069714..3070731,3070823..3071504,3071569..3071764,3072156..3072308); ID=FBpp0111796; name=toc-PF; parent=FBgn0015600,FBtr0112883; dbxref=FlyBase:FBpp0111796,FlyBase_Annotation_IDs:CG9660-PF,REFSEQ:NP_001097064,GB_protein:ABV53609,FlyMine:FBpp0111796,modMine:FBpp0111796; MD5=732b0d6869d55fa0dc0024cf074050e6; length=682; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta] type=protein; loc=2L:complement(join(3072156..3072308,3071569..3071764,3070823..3071504,3069714..3070731)); ID=FBpp0111796; name=toc-PF; parent=FBgn0015600,FBtr0112883; dbxref=FlyBase:FBpp0111796,FlyBase_Annotation_IDs:CG9660-PF,REFSEQ:NP_001097064,GB_protein:ABV53609,FlyMine:FBpp0111796,modMine:FBpp0111796; MD5=732b0d6869d55fa0dc0024cf074050e6; length=682; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta] type=protein; loc=2L:complement(join(3072156..3072308,3071569..3071764,3070823..3071504,3069714..3070731)); ID=FBpp0111796; name=toc-PF; parent=FBgn0015600,FBtr0112883; dbxref=FlyBase:FBpp0111796,FlyBase_Annotation_IDs:CG9660-PF,REFSEQ:NP_001097064,GB_protein:ABV53609,FlyMine:FBpp0111796,modMine:FBpp0111796; MD5=732b0d6869d55fa0dc0024cf074050e6; length=682; release=r6.07; species=Dmel; [fly-08202015-contam.fasta] Isoform of Q9VQM0, Toucan, isoform F OS=Drosophila melanogaster GN=toc PE=4 SV=1 [DROME.fasta.20160308] FBpp0111796 type=protein; loc=2L:complement(join(3072156..3072308,3071569..3071764,3070823..3071504,3069714..3070731)); ID=FBpp0111796; name=toc-PF; parent=FBgn0015600,FBtr0112883; dbxref=FlyBase:FBpp0111796,FlyBase_Annotation_IDs:CG9660-PF,REFSEQ:NP_001097064,GB_protein:ABV53609,FlyMine:FBpp0111796,modMine:FBpp0111796; MD5=732b0d6869d55fa0dc0024cf074050e6; length=682; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta] [fly-122215-dmel-6-09-contam.fasta] type=protein; loc=2L:complement(join(3072156..3072308,3071569..3071764,3070823..3071504,3069714..3070731)); ID=FBpp0111796; name=toc-PF; parent=FBgn0015600,FBtr0112883; dbxref=FlyBase:FBpp0111796,FlyBase_Annotation_IDs:CG9660-PF,REFSEQ:NP_001097064,GB_protein:ABV53609,UniProt/TrEMBL:A8DYU0,FlyMine:FBpp0111796,modMine:FBpp0111796; MD5=732b0d6869d55fa0dc0024cf074050e6; length=682; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
Organism:	Drosophila melanogaster
Length:	682 amino acids
Gene Ontology:
Cellular Component:	nucleus [IDA][NAS] spindle microtubule [NAS] nuclear membrane [IDA] centrosome [IDA] cell cortex [IDA] spindle [IDA] spindle pole [IDA] midbody [IDA]
Biological Process:	ovarian follicle cell development [TAS] mitotic spindle organization [NAS] syncytial blastoderm mitotic cell cycle [IMP] proteolysis [IEA] mitotic sister chromatid segregation [NAS]
Molecular Function:	protein kinase binding [NAS] cysteine-type endopeptidase activity [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFENFEFTNE NLSAQTMDLD IDLISWTVPS TPTSTTFTDN FNFAQAFEEQ QLDAVACKEN  60
   61 KHQCARTKGT LEKTILLLQH TQKDCERLRE DLEDKGLEWI QRQQEKEYLH RTELKQAEEK 120
  121 LMEVQLRAKL KFCELESQLR AKDEESKQAQ EAYRMEVSHK LALKQEHLRT AEQKIQELQT 180
  181 RLQQVETEEQ GHREELIRKE NIHTARLAEA NQREQDLIDR VKSLTKELNT LKANKEHNER 240
  241 DLRDRLALSQ DEISVLRTSS QRRSPCTSLP DNASAELNRL TSEADSLRCV LELKQAEISA 300
  301 LSKAKADLIH ESEERLKLSN RVALLEAQNE MLRTELEAKT EKEKEIQQKM EELQKAYKYE 360
  361 SIKRTRLTYD KEELQYHLKQ RSLQLQSAES KLQDLSTGSH DNSLSSHSRC SLGRSGLEIA 420
  421 VTTSSPTSPV MKGMIERNDS VSWTLEIEDE SFKGNTSKIV RRAGSLRSNN ERCPIQRRQT 480
  481 LTSNGHSNGS ATNGGSSPAH PNPLSQSMSA TALLRSSSNS GESEGRPLSR ARSKSMCIKA 540
  541 SATSSAVCES SGQRKKPQDE LSLADWPEDI PLCSSSPQAP GIEMRPRSST MKLMSSEAKK 600
  601 FQEIQESAGE AMVSGANSED ESCSASSEDI MRSSSASSTA SGGSLSKRPK QPPSRMSIEE 660
  661 ALPCTPMEVS WSEDAADANG LA

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Protein Overview: toc-PF

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: