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Protein Overview: TKN1_RAT

General Information:
Name(s) found: TKN1_RAT [Swiss-Prot]
Description(s) found:
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  • gi|6981626|ref|NP_036798.1| tachykinin 1 isoform a [Rattus norvegicus] [NCBI NR]
  • gi|6226545|sp|P06767.2|TKN1_RAT RecName: Full=Protachykinin-1; AltName: Full=PPT; Contains: RecName: Full=Substance P; Contains: RecName: Full=Neurokinin A; Short=NKA; AltName: Full=Substance K; AltName: Full=Neuromedin L; Contains: RecName: Full=Neuropep [NCBI NR]
  • gi|206342|gb|AAA41928.1| beta-preprotachykinin [NCBI NR]
  • gi|206336|gb|AAA41926.1| beta-preprotachykinin (PPT) [NCBI NR]
  • gi|149064969|gb|EDM15045.1| tachykinin 1, isoform CRA_a [Rattus norvegicus] [NCBI NR]
  • pir||SPRTB substance P beta precursor - rat [NCBI NR]
  • Protachykinin-1 OS=Rattus norvegicus GN=Tac1 PE=2 SV=2 [Swiss-Prot]
  • tachykinin 1; Tachykinin (substance P, neurokinin A, neuropeptide K, neuropeptide gamma); Tachykinin (substance P neurokinin A neuropeptide K neuropeptide gamma) [HMR_022704-rand.fasta]
  • tachykinin 1 [Rattus norvegicus]gi|6226545|sp|P06767|TKN1_RAT Protachykinin 1 precursor (PPT) [Contains: Substance P; Neurokinin A (NKA) (Substance K) (Neuromedin L); Neuropeptide K (NPK); Neuropeptide gamma; C-terminal flanking peptide]gi|1070558|pir|| [nrdb_11152004_Chlamydomonas]
  • Tax_Id=10116 Splice Isoform Beta of Protachykinin 1 precursor [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta]
  • (NM_012666) tachykinin (substance P, neurokinin A, neuropeptide K, neuropeptide gamma) [Rattus norvegicus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta]
  • tachykinin 1 isoform a [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • Protachykinin-1 precursor (PPT) [Contains: Substance P; Neurokinin A (NKA) (Substance K) (Neuromedin L); Neuropeptide K (NPK); Neuropeptide gamma; C-terminal-flanking peptide] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • tachykinin 1, isoform CRA_a [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • beta-preprotachykinin [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • beta-preprotachykinin (PPT) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • Tax_Id=10116 SPLICE ISOFORM 1 OF PROTACHYKININ 1 PRECURSOR [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta]
  • Protachykinin 1 precursor (PPT) [Contains: Substance P; Neurokinin A (NKA) (Substance K) (Neuromedin L); Neuropeptide K (NPK); Neuropeptide gamma; C-terminal-flanking peptide] [nr-271106-contam.fasta]
  • tachykinin 1 [Rattus norvegicus] [nr-271106-contam.fasta]
  • Tax_Id=10116 Gene_Symbol=Tac1 Isoform Beta of Protachykinin-1 [rat-ipi-250309-contam.fasta]
  • protachykinin-1 isoform a [Rattus norvegicus] [NCBI-RefSeq_Human_na_04-23-2010_reversed.fasta]
  • Isoform Beta of Protachykinin-1 OS=Rattus norvegicus GN=Tac1 [011711_HMR.fasta]
    • Organism: Rattus norvegicus
    Length: 130 amino acids

    Gene Ontology:
    Cellular Component: extracellular space [IDA]
    neuronal cell body [UNKNOWN][IEA]
    extracellular region [UNKNOWN][IEA]
    plasma membrane [IDA]
    axon [UNKNOWN][IEA]
    Biological Process: positive regulation of synaptic transmission, GABAergic [IDA]
    synaptic transmission [IEA]
    response to morphine [IEP]
    associative learning [IDA]
    response to hormone stimulus [IMP]
    positive regulation of natriuresis [IDA]
    tachykinin receptor signaling pathway [IEA]
    regulation of blood pressure [IDA]
    elevation of cytosolic calcium ion concentration [UNKNOWN][IDA]
    positive regulation of ossification [IDA]
    positive regulation of acute inflammatory response [IDA]
    long-term memory [IDA]
    response to pain [UNKNOWN][IEA]
    inflammatory response [UNKNOWN][IEA]
    neuropeptide signaling pathway [IEA]
    positive regulation of action potential [IDA]
    positive regulation of lymphocyte proliferation [IMP]
    positive regulation of stress fiber assembly [IDA]
    sensory perception of pain [UNKNOWN][IEA]
    positive regulation of synaptic transmission, cholinergic [IDA]
    negative regulation of heart rate [IDA]
    response to lipopolysaccharide [IEP]
    positive regulation of epithelial cell migration [IDA]
    Molecular Function: substance P receptor binding [IDA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKILVAVAVF FLVSTQLFAE EIGANDDLNY WSDWSDSDQI KEAMPEPFEH LLQRIARRPK  60
   61 PQQFFGLMGK RDADSSIEKQ VALLKALYGH GQISHKRHKT DSFVGLMGKR ALNSVAYERS 120
  121 AMQNYERRRK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..130] deduced N/A No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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