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The process by which acetylcholine released from vagus nerve endings binds to muscarinic receptors on the pacemaker cells and decreases the rate of heart muscle contraction. Any process that stops, prevents or reduces the frequency or rate of heart contraction. The multicellular organismal process by which the heart decreases in volume in a characteristic way to propel blood through the body. Any process that stops, prevents or reduces the frequency, rate or extent of heart contraction as a result of the baroreceptor response to increased blood pressure. Any process that modulates the frequency or rate of heart contraction. Any process that stops, prevents or reduces the frequency, rate or extent of an organismal process, the processes pertinent to the function of an organism above the cellular level; includes the integrated processes of tissues and organs. Any process that modulates the frequency, rate or extent of heart contraction. Heart contraction is the process by which the heart decreases in volume in a characteristic way to propel blood through the body. Any process that modulates the frequency, rate or extent of a biological quality. A biological quality is a measurable attribute of an organism or part of an organism, such as size, mass, shape, color, etc. Any process that stops, prevents or reduces the frequency, rate or extent of heart contraction.

View Gene Ontology (GO) Term

GO TERM SUMMARY

Name: negative regulation of heart rate
Acc: GO:0010459
Aspect: Biological Process
Desc: Any process that stops, prevents or reduces the frequency or rate of heart contraction.
Proteins in PDR annotated with:
   This term: 4 [Search]
   Term or descendants: 6 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0010459 - negative regulation of heart rate (interactive image map)

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