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Protein Overview: TFR1_RAT

General Information:
Name(s) found: TFR1_RAT [Swiss-Prot]
Description(s) found:
Found 9 descriptions.
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  • Transferrin receptor protein 1 (Fragment) OS=Rattus norvegicus GN=Tfrc PE=2 SV=1 [Swiss-Prot]
    • Organism: Rattus norvegicus
    Length: 622 amino acids

    Gene Ontology:
    Cellular Component: endosome [UNKNOWN][IEA]
    perinuclear region of cytoplasm [UNKNOWN][IEA]
    extracellular vesicular exosome [UNKNOWN]
    melanosome [IEA]
    coated pit [UNKNOWN][IEA]
    mitochondrion [IDA]
    integral to membrane [IEA]
    cytoplasmic membrane-bounded vesicle [UNKNOWN][IEA]
    extracellular region [UNKNOWN][IEA]
    plasma membrane [UNKNOWN][IDA]
    Biological Process: response to manganese ion [IEP]
    response to organic substance [IEP]
    response to copper ion [IEP]
    response to nutrient [IEP]
    endocytosis [IEA]
    aging [IEP]
    acute-phase response [IEP]
    cellular iron ion homeostasis [UNKNOWN][IEA]
    response to retinoic acid [IEP]
    response to hypoxia [IEP]
    proteolysis [IEA]
    response to iron ion [IEP]
    response to inorganic substance [IEP]
    Molecular Function: transferrin receptor activity [IDA][TAS]
    peptidase activity [IEA]
    receptor activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IEFTDIIKQL SQNTYTPREA GSQKDENLAY YIENLFHDFK FSKVWRDEHY VKIQVKNSVS  60
   61 QNLVTINSGS NIDPVEAPEG YVAFSKAGEV TGKLVHANFG TKKDFEELNY SVNGSLVIVR 120
  121 AGKITFAEKV ANAQSFNAIG VLIYMDRNTF PVVEADLQFF GHAHLGTGDP YTPGFPSFNH 180
  181 TQFPPSQSSG LPSIPVQTIS RAPAEKLFKN MEGNCPPSWN IDSSCKLELS QNQNVKLTVN 240
  241 NVLKETRILN IFGVIKGYEE PDRYIVVGAQ RDAWGPGVAK SSVGTGLLLK LAQVFSDMIS 300
  301 KDGFRPSRSI IFASWTAGDY GAVGPTEWLE GYLSSLHLKA FTYINLDKVV LGTSNFKVSA 360
  361 SPLLYTLMGK IMQDVKHPID GKYLYRNSNW ISKIEELSLD NAAFPFLAYS GIPAVSFCFC 420
  421 EDEDYPYLGT KLDTYEILIQ KVPQLNQMVR TAAEVAGQFI IKLTHDIELT LDYEMYNSKL 480
  481 LSFMKDLNQF KADIKDMGLS LQWLYSARGD YFRATSRLTT DFHNAEKTNR FVMREINDRI 540
  541 MKVEYHFLSP YVSPRESPFR HIFWGSGSHT LSALVENLRL RQKNITAFNE TLFRNQLALA 600
  601 TWTIQGVANA LSGDIWNIDN EF

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.91

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle