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Protein Overview: RUVA_ECOLI

General Information:
Name(s) found: RUVA_ECOLI [Swiss-Prot]
Description(s) found:
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  • gi|9955149|pdb|1C7Y|A Chain A, E.Coli Ruva-Holliday Junction Complex [NCBI NR]
  • pir||BVECRV ruvA protein - Escherichia coli (strain K-12) [NCBI NR]
  • gi|67472389|sp|P0A809.1|RUVA_ECOLI RecName: Full=Holliday junction ATP-dependent DNA helicase ruvA [NCBI NR]
  • gi|5107497|pdb|1BDX|D Chain D, E. Coli Dna Helicase Ruva With Bound Dna Holliday Junction, Alpha Carbons And Phosphate Atoms Only [NCBI NR]
  • gi|5107496|pdb|1BDX|C Chain C, E. Coli Dna Helicase Ruva With Bound Dna Holliday Junction, Alpha Carbons And Phosphate Atoms Only [NCBI NR]
  • gi|5107495|pdb|1BDX|B Chain B, E. Coli Dna Helicase Ruva With Bound Dna Holliday Junction, Alpha Carbons And Phosphate Atoms Only [NCBI NR]
  • gi|5107494|pdb|1BDX|A Chain A, E. Coli Dna Helicase Ruva With Bound Dna Holliday Junction, Alpha Carbons And Phosphate Atoms Only [NCBI NR]
  • gi|2982097|pdb|1HJP| Chain , Holliday Junction Binding Protein Ruva From E. Coli [NCBI NR]
  • pir||G85798 Holliday junction DNA helicase ruvA - Escherichia coli (strain O157:H7, substrain EDL933) [NCBI NR]
  • pir||C90950 Holliday junction helicase subunit B [imported] - Escherichia coli (strain O157:H7, substrain RIMD 0509952) [NCBI NR]
  • gi|209767476|gb|ACI82050.1| Holliday junction helicase subunit B [Escherichia coli] [NCBI NR]
  • gi|209767474|gb|ACI82049.1| Holliday junction helicase subunit B [Escherichia coli] [NCBI NR]
  • gi|209767472|gb|ACI82048.1| Holliday junction helicase subunit B [Escherichia coli] [NCBI NR]
  • gi|209767470|gb|ACI82047.1| Holliday junction helicase subunit B [Escherichia coli] [NCBI NR]
  • gi|209767468|gb|ACI82046.1| Holliday junction helicase subunit B [Escherichia coli] [NCBI NR]
  • gi|1736508|dbj|BAA15672.1| component of RuvABC resolvasome, regulatory subunit [Escherichia coli W3110] [NCBI NR]
  • gi|157831340|pdb|1HJP|A Chain A, Holliday Junction Binding Protein Ruva From E. Coli [NCBI NR]
  • gi|147782|gb|AAA24612.1| ruvA protein (gtg start) [NCBI NR]
  • Holliday junction ATP-dependent DNA helicase ruvA (EC 3.6.1.-) - Escherichia coli [Swiss-Prot]
  • Holliday junction helicase subunit B; branch migration; repair; Holliday junction helicase, subunit A [Escherichia coli K12]gi|15831825|ref|NP_310598.1| Holliday junction helicase subunit B [Escherichia coli O157:H7]gi|26248127|ref|NP_754167.1| Holliday [nrdb_11152004_Chlamydomonas]
  • Holliday junction ATP-dependent DNA helicase ruvA [NCBI-RefSeq_human_na_08-09-2006_reversed.fasta]
  • Chain , Holliday Junction Binding Protein Ruva From E. Coli [nr-271106-contam.fasta]
  • Chain A, E.Coli Ruva-Holliday Junction Complex [nr-271106-contam.fasta]
  • ruvA protein (gtg start) [nr-271106-contam.fasta]
  • Holliday junction ATP-dependent DNA helicase ruvA OS=Escherichia coli (strain K12) GN=ruvA PE=1 SV=1 [uniprot-Ecoli-reviewed-110511.fasta]
  • Holliday junction ATP-dependent DNA helicase RuvA OS=Escherichia coli (strain K12) GN=ruvA PE=1 SV=1 [uniprot_sprot.fasta.20160308]
    • Organism: Escherichia coli
    Length: 203 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIGRLRGIII EKQPPLVLIE VGGVGYEVHM PMTCFYELPE AGQEAIVFTH FVVREDAQLL  60
   61 YGFNNKQERT LFKELIKTNG VGPKLALAIL SGMSAQQFVN AVEREEVGAL VKLPGIGKKT 120
  121 AERLIVEMKD RFKGLHGDLF TPAADLVLTS PASPATDDAE QEAVAALVAL GYKPQEASRM 180
  181 VSKIARPDAS SETLIREALR AAL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..203] PSI-BLAST 62.154902 DNA helicase RuvA subunit, C-terminal domain; DNA helicase RuvA subunit, middle domain; DNA helicase RuvA subunit, N-terminal domain

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • four-way junction helicase activity
    		•  6.5377357736202 bayes_pls_golite062009
  • DNA helicase activity
    		•  4.17140899815273 bayes_pls_golite062009
  • endodeoxyribonuclease activity
    		•  3.43738564958931 bayes_pls_golite062009
  • helicase activity
    		•  3.41619150983834 bayes_pls_golite062009
  • deoxyribonuclease activity
    		•  3.18777140839084 bayes_pls_golite062009
  • excinuclease ABC activity
    		•  2.75922711242844 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.99569639221804 bayes_pls_golite062009
  • structure-specific DNA binding
    		•  1.68542948433544 bayes_pls_golite062009
  • binding
    		•  1.60192408330567 bayes_pls_golite062009
  • single-stranded DNA binding
    		•  1.58506920916947 bayes_pls_golite062009
  • DNA binding
    		•  1.33645375386113 bayes_pls_golite062009
  • endonuclease activity
    		•  1.07194065760938 bayes_pls_golite062009
  • damaged DNA binding
    		•  1.01799678384131 bayes_pls_golite062009
  • ATP-dependent DNA helicase activity
    		•  1.01626429465845 bayes_pls_golite062009
  • structural constituent of ribosome
    		•  0.83740886071361 bayes_pls_golite062009
  • structural molecule activity
    		•  0.53636537261201 bayes_pls_golite062009
  • nuclease activity
    		•  0.29926900436997 bayes_pls_golite062009
  • exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters
    		•  0.0954216620147701 bayes_pls_golite062009
  • exonuclease activity
    		•  0.0152988330656798 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.96

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle