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Protein Overview: EXOS3_MOUSE

General Information:
Name(s) found: EXOS3_MOUSE [Swiss-Prot]
Description(s) found:
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  • gi|54311132|gb|AAH23669.1| Exosome component 3 [Mus musculus] [NCBI NR]
  • gi|46577373|sp|Q7TQK4.3|EXOS3_MOUSE RecName: Full=Exosome complex exonuclease RRP40; AltName: Full=Ribosomal RNA-processing protein 40; AltName: Full=Exosome component 3 [NCBI NR]
  • gi|39930417|ref|NP_079789.1| exosome component 3 [Mus musculus] [NCBI NR]
  • gi|32484211|gb|AAH54085.1| Exosome component 3 [Mus musculus] [NCBI NR]
  • gi|148670453|gb|EDL02400.1| exosome component 3, isoform CRA_a [Mus musculus] [NCBI NR]
  • gi|123858115|emb|CAM26865.1| exosome component 3 [Mus musculus] [NCBI NR]
  • (Q7TQK4) Exosome complex exonuclease RRP40 (EC 3.1.13.-) (Ribosomal RNA processing protein 40) (Exosome component 3) [Swiss-Prot]
  • Exosome complex component RRP40 OS=Mus musculus GN=Exosc3 PE=1 SV=3 [Swiss-Prot]
  • exosome component 3 [HMR_022704-rand.fasta]
  • Exosome complex exonuclease RRP40 [ipi.MOUSE.v3.06.fasta]
  • Exosome component 3 [Mus musculus]gi|39930417|ref|NP_079789.1| exosome component 3 [Mus musculus]gi|32484211|gb|AAH54085.1| Exosome component 3 [Mus musculus]gi|46577373|sp|Q7TQK4|RR40_MOUSE Exosome complex exonuclease RRP40 (Ribosomal RNA processing p [nrdb_11152004_Chlamydomonas]
  • exosome component 3 [Mus musculus] [mouse-NCBI-010306_contam_rand.fasta]
  • Tax_Id=10090 Exosome complex exonuclease RRP40 [EBI-IPI_mouse_3.06_05-10-2005_origrev_con.fasta]
  • Exosome complex exonuclease RRP40 (Ribosomal RNA-processing protein 40) (Exosome component 3) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • exosome component 3, isoform CRA_a [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • Exosome component 3 [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • Tax_Id=10090 EXOSOME COMPLEX EXONUCLEASE RRP40 [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta]
  • Tax_Id=10090 Gene_Symbol=Exosc3 Exosome complex exonuclease RRP40 [mouse-ipi-250309-contam.fasta]
  • Tax_Id=10090 Gene_Symbol=Exosc3 Exosome complex exonuclease RRP40 ENSMUSG00000028322 IPI00396812 IPI00648702 [IPIxENS.MOUSE_plus_REVERSE.fasta]
  • exosome complex exonuclease RRP40 [Mus musculus] [NCBI-RefSeq_mouse_na_05-17-2010_reversed.fasta]
  • IPI:IPI00396812.3|SWISS-PROT:Q7TQK4|TREMBL:A2AKB8|ENSEMBL:ENSMUSP00000030003|REFSEQ:NP_079789|VEGA:OTTMUSP00000008050 Tax_Id=10090 Gene_Symbol=Exosc3 Exosome complex exonuclease RRP40 [ipi.MOUSE.fasta.20090209]
  • Exosome complex exonuclease RRP40 OS=Mus musculus GN=Exosc3 [011711_HMR.fasta]
  • Exosome complex exonuclease RRP40 OS=Mus musculus GN=Exosc3 PE=2 SV=3 [UniProt_mouse_sprotvarsplic_11-08-2010_reversed.fasta]
  • Exosome complex component RRP40 OS=Mus musculus GN=Exosc3 [122011_mus.fasta]
  • Tax_Id=10090 Gene_Symbol=Exosc3 Exosome complex component RRP40 [EBI-IPI_mouse_2_08-18-2011_reversed.fasta]
  • sp|Q7TQK4|EXOS3_MOUSE Exosome complex component RRP40 OS=Mus musculus GN=Exosc3 PE=1 SV=3 [uniprot.sptr.mouse.20130102]
  • tr|A2AKB8|A2AKB8_MOUSE Exosome component 3 OS=Mus musculus GN=Exosc3 PE=4 SV=1 [uniprot.sptr.mouse.20130102]
  • Exosome component 3 OS=Mus musculus GN=Exosc3 PE=4 SV=1 [UniProt_mouse_01-27-2011_reversed.fasta]
    • Organism: Mus musculus
    Length: 274 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAEVLSAGPE SVAGCRARAV HKVLNQVVLP GEELVLPDHE DVDGLGGAGE QPLRLNAGAR  60
   61 PRLRVVCGPG LRRCGDRLLV TKCGRLRHKE PSGGGGGVYW VDSQQKRYVP VKGDHVIGIV 120
  121 IAKSGDIFKV DVGGSEPASL SYLAFEGATK RNRPNVQVGD LIYGQCVVAN KDMEPEMVCI 180
  181 DSCGRANGMG VIGQDGLLFK VTLGLIRKLL APDCEIVQEL GKLYPLEIVF GMNGRIWVKA 240
  241 KTIQQTLILA NVLEACEHMT TEQRKQIFAR LAES

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..274] PSI-BLAST 86.69897 No description for 2nn6G was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • RNA binding
    		•  4.49437316734899 bayes_pls_golite062009
  • structural constituent of ribosome
    		•  3.89236528662255 bayes_pls_golite062009
  • nucleic acid binding
    		•  3.68444148122352 bayes_pls_golite062009
  • structural molecule activity
    		•  3.54418030121155 bayes_pls_golite062009
  • 3'-5'-exoribonuclease activity
    		•  3.40736445988244 bayes_pls_golite062009
  • exoribonuclease activity, producing 5'-phosphomonoesters
    		•  3.3097066639101 bayes_pls_golite062009
  • exoribonuclease activity
    		•  3.27082657120932 bayes_pls_golite062009
  • binding
    		•  2.8667878224392 bayes_pls_golite062009
  • mRNA binding
    		•  2.83121485081867 bayes_pls_golite062009
  • ribonuclease activity
    		•  1.89205340530046 bayes_pls_golite062009
  • 3'-5' exonuclease activity
    		•  1.55351486913613 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.43703138180882 bayes_pls_golite062009
  • exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters
    		•  1.42151567812515 bayes_pls_golite062009
  • aminoacyl-tRNA ligase activity
    		•  1.35850109411274 bayes_pls_golite062009
  • ligase activity, forming aminoacyl-tRNA and related compounds
    		•  1.35845277283398 bayes_pls_golite062009
  • ligase activity, forming carbon-oxygen bonds
    		•  1.35845277283398 bayes_pls_golite062009
  • exonuclease activity
    		•  1.25488463068335 bayes_pls_golite062009
  • DNA binding
    		•  1.20852534725468 bayes_pls_golite062009
  • protein binding
    		•  1.18834207917479 bayes_pls_golite062009
    		• 0.559294837259864 bayes_pls_golite062009
  • transcription factor activity
    		•  0.386248501195543 bayes_pls_golite062009
  • ligase activity
    		•  0.346041081217685 bayes_pls_golite062009
  • structure-specific DNA binding
    		•  0.32222928997178 bayes_pls_golite062009
  • hydrolase activity, acting on ester bonds
    		•  0.246726936182314 bayes_pls_golite062009
  • aspartate-tRNA ligase activity
    		•  0.151650064901878 bayes_pls_golite062009
  • translation initiation factor activity
    		•  0.11625379846973 bayes_pls_golite062009
  • catalytic activity
    		•  0.113112541746059 bayes_pls_golite062009
  • single-stranded DNA binding
    		•  0.1069917291606 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.96

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle