Protein Overview: gi|149040719, gi...

General Information:
Name(s) found:	gi\|189441883 [NCBI NR] gi\|149040719 [NCBI NR]
Description(s) found: Found 6 descriptions. SHOW ALL	gi\|189441883\|gb\|AAI67747.1\| Ncstn protein [Rattus norvegicus] [NCBI NR] gi\|149040719\|gb\|EDL94676.1\| nicastrin, isoform CRA_b [Rattus norvegicus] [NCBI NR]
Organism:	Rattus norvegicus
Length:	602 amino acids
Gene Ontology:
Cellular Component:	membrane fraction [UNKNOWN][IEA] integral to plasma membrane [UNKNOWN][ISS] melanosome [IEA] endoplasmic reticulum [UNKNOWN][ISS] Golgi apparatus [UNKNOWN][ISS] lysosomal membrane [IDA] plasma membrane [UNKNOWN][IEA]
Biological Process:	Notch signaling pathway [IEA] membrane protein ectodomain proteolysis [UNKNOWN][ISS] positive regulation of catalytic activity [UNKNOWN][ISS] membrane protein intracellular domain proteolysis [UNKNOWN] apoptosis [UNKNOWN] protein processing [UNKNOWN][IEP][ISS] induction of apoptosis by extracellular signals [UNKNOWN]
Molecular Function:	protein binding [UNKNOWN][IPI] peptidase activity [IPI]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEKLKGETSR IAGLAVTLAK PNSTSSFSPS VQCPNDGFGI YSNSYGPEFA HCKKTLWNEL  60
   61 GNGLAYDDFS FPIFLLEDEN ETKVIKQCYQ DHNLGQNGSA PSFPLCAMQL FSHMHAVIST 120
  121 ATCMRRSFIQ STFSINPEIV CDPLSDYNVW SMLKPINTSG GLEPDVRVVV AATRLDSRSF 180
  181 FWNVAPGAES AVASFVTQLA AAEALHKAPD VTTLPRNVMF VFFQGETFDY IGSSRMVYDM 240
  241 ENGKFPVRLE NIDSFVELGQ VALRTSLELW MHTDPMSQKN ESVKNQVEDL LVTLEQSGAD 300
  301 TPQVVLSRLV QSQALPPSSL QRFLRARNIS GVVLADHSGS FHNRYYQSIY DTAENINVTY 360
  361 PESQSPEEDL NFVTDTAKAL ADVATVLARA LYKLAGGTNF NNSIQADPQT VTRLLYGFLV 420
  421 RANNSWFQSI LRHDLRSYLD DGPLQHYIAV SSPTNTTYVV QYALANLTGK VTNLTQEQCQ 480
  481 DPSKVPNESK DLYEYSWVQG PWNSNKTERL PRCVRSTVRL ARALSPAFEL SQWSSTEYST 540
  541 WAESRWKDIQ ARIFLIASKE LEFITLIVGF SILVFSLIVT YCINAKADVL FVAPREPGAV 600
  601 SY

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: gi|149040719, gi...

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: