YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

Protein Overview: gi|149041498, gi...

General Information:
Name(s) found: gi|157822483 [NCBI NR]
gi|149041498 [NCBI NR]
Description(s) found:
Found 9 descriptions.
SHOW ALL
  • gi|157822483|ref|NP_001101609.1| myeloid/lymphoid or mixed-lineage leukemia 1 [Rattus norvegicus] [NCBI NR]
  • gi|149041498|gb|EDL95339.1| myeloid/lymphoid or mixed-lineage leukemia (mapped) [Rattus norvegicus] [NCBI NR]
    • Organism: Rattus norvegicus
    Length: 3725 amino acids

    Gene Ontology:
    Cellular Component: nucleus [UNKNOWN][IEA]
    nuclear part [UNKNOWN]
    histone methyltransferase complex [UNKNOWN][IEA]
    cellular_component [ND]
    MLL1 complex [UNKNOWN]
    Biological Process: chromatin modification [IEA]
    biological_process [ND]
    protein complex assembly [UNKNOWN]
    embryonic hemopoiesis [UNKNOWN]
    negative regulation of cell proliferation [UNKNOWN]
    anterior/posterior pattern formation [UNKNOWN]
    regulation of transcription, DNA-dependent [IEA]
    positive regulation of transcription from RNA polymerase II promoter [UNKNOWN]
    histone H4-K16 acetylation [UNKNOWN]
    DNA methylation [UNKNOWN]
    positive regulation of transcription, DNA-dependent [UNKNOWN]
    regulation of histone H3-K4 methylation [UNKNOWN]
    histone H3-K4 methylation [UNKNOWN]
    Molecular Function: histone methyltransferase activity (H3-K4 specific) [UNKNOWN][IEA]
    DNA binding [IEA]
    zinc ion binding [UNKNOWN][IEA]
    identical protein binding [UNKNOWN]
    protein binding [UNKNOWN][IEA]
    protein homodimerization activity [UNKNOWN]
    histone acetyl-lysine binding [UNKNOWN]
    unmethylated CpG binding [UNKNOWN]
    chromatin binding [UNKNOWN]
    molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFQQATKIKK LRAGKLSPLK SKFKTGKLQI GRKGVQIVRR RGRPPSTERI KTPSGLLINS  60
   61 ELEKPQKVRK DKEGTPPLTK EDKTVVRQSP RRIKPVRIIP SSKRTDATIA KQLLQRAKKG 120
  121 AQKKIEKEAA QLQGRKVKTQ VKNIRQFIMP VVSAISSRII KTPRRFIEDE DYDPPIKIAR 180
  181 LESTPNSRFS ATSCGSSEKS SAASQHSSQM SSDSSRSSSP SIDTTSDSQA SEEIQALPEE 240
  241 RSNTPEVHTP LPISQSPENE SNDRRGRRYS MSERSFGSRT TKKLPTLQSA PQQQTSSSPP 300
  301 PPLLTPPPPL QPASGISDHT PWLMPPTIPL ASPFLPASAA PMQGKRKSIL REPTFRWTSL 360
  361 KHSRSEPQYF SSAKYAKEGL IRKPIFDNFR PPPLTPEDVG FASGFSASGS AASARLFSPL 420
  421 HSGTRFDIHK RSPILRAPRF TPSEAHSRIF ESVTLPSNRT SSGASSSGVS NRKRKRKVFS 480
  481 PIRSEPRSPS HSMRTRSGRL STSELSPLTP PSSVSSSLSI PVSPLAASAL NPTFTFPSHS 540
  541 LTQSGESTEK SQRARKQTSA PAEPFSSNSP ALFPWFTPGS QTEKGRKKDT APEELSKDRD 600
  601 ADKSVEKDKS RERDREREKE NKRESRKEKR KKGSDIQSSS ALYPVGRVSK EKVAGEDVGT 660
  661 SSSAKKATGR KKSSSLDSGA DIAPVTLGDT TAVKAKILIK KGRGNLEKNN LDLGPTAPSL 720
  721 EKEKTLCLST PSPSTVKHST SSIGSMLAQA DKLPMTDKRV ASLLKKAKAQ LCKIEKSKSL 780
  781 KQTDQPKAQG QESDSSETSV RGPRIKHVCR RAAVALGRKR AVFPDDMPTL SALPWEEREK 840
  841 ILSSMGNDDK SSIAGSEDAE PLAPPIKPIK PVTRNKAPQE PPVKKGRRSR RCGQCPGCQV 900
  901 PEDCGVCTNC LDKPKFGGRN IKKQCCKMRK CQNLQWMPSK AYLQKQTKAV KKKEKKSKAT 960
  961 EKKESKESTV VKSSLESAQK AAPPVREEPA PKKSSSEPPP RKPVEEKTEE GGAPAPAPAP1020
 1021 APAPAPAPAP APAPAPAPEP KQASTPASRK SSKQVSQPAA VVPPQPPSTA LQKKEAPKAI1080
 1081 PSEPKKKQPP PPESGPEQSK QKKVAPRPSI PVKQKPKDKE KPPPVSKQEN AGTLNILNPL1140
 1141 LNGISSKQKI PADGVHRIRV DFKEDCEAEN VWEMGGLGIL TSVPITPRVV CFLCASSGHV1200
 1201 EFVYCQVCCE PFHKFCLEEN ERPLEDQLEN WCCRRCKFCH VCGRQHQATK QLLECNKCRN1260
 1261 SYHPECLGPN YPTKPTKKKK VWICTKCVRC KSCGSTTPGK GWDAQWSHDF SLCHDCAKLF1320
 1321 AKGNFCPLCD KCYDDDDYES KMMQCGKCDR WVHSKCEGLS GTEDEMYEIL SNLPESVAYT1380
 1381 CVNCTERHPA EWRLALEKEL QASLKQVLTA LLNSRTTSHL LRYRQAAKPP DLNPETEESI1440
 1441 PSRSSPEGPD PPVLTEVSKQ DEQQPLDLEG VKKKMDQGNY VSVLEFSDDI VKIIQAAINS1500
 1501 DGGQPEIKKA NSMVKSFFIR QMERVFPWFS VKKSRFWEPN KVSNNSGMLP NAVLPPSLDH1560
 1561 NYAQWQEREE SSHTEQPPLM KKIIPAPKPK GPGEPDSPTP LHPPTPPILS TDRSREDSPE1620
 1621 LHPPPGIDDN RQCALCLMYG DDSANDAGRL LYIGQNEWTH VNCALWSAEV FEDDDGSLKN1680
 1681 VHMAVIRGKQ LRCEFCQKPG ATVGCCLTSC TSNYHFMCSR AKNCVFLDDK KVYCQRHRDL1740
 1741 IKGEVVPENG FEVFRRVFVD FEGISLRRKF LNGLEPESVH VMIGSMTIDC LGILNDLSDC1800
 1801 EDKLFPIGYQ CSRVYWSTTD ARKRCVYTCK IMECRPPVVE PDINSTVEHD DNRTIAHSPS1860
 1861 SFIEASCKDS QSTAAILSPP SPDRPRSQAS SSCYCHVISK VPRIRTPSYS PTQRSPGCRP1920
 1921 LPSAGSPTPT THEIVTVGDP LLSSGLRSIG SRRHSTSSLS PLRSKLRIMS PVRSGSVYSR1980
 1981 SSVSSVPSLG TATDPESSAK ATDRAGPLNS SANLGHSTPV SSGSQRTVVT GGSKTSHLDG2040
 2041 SSSSGVKRSS ASDLAPKGSS LKGEKNRTPG SKSTDGSAHN TAYSGIPKLA PQVLNAAPGE2100
 2101 LNVSKIGTFA EPSTVPFSKE TVSYPQLHLR GQRSDRDQHM DSTQSVKPSP NEDGEIKTLK2160
 2161 LPGMGHRPSI LHEHVGSSSR DRRQKGKKSS KETCKEKHSS KSFLEPGQVT TGEEGNLKPE2220
 2221 FADEVLTPGF LGQRPCNNVS SDKTGDKILP LSGVPKGQST QVEGSSKELQ APRKCSVKVT2280
 2281 PLKMESENQS KNTQKESGPG SPAHMESACP AEPASASRSP GAGPGVQPSP NNTSSQDPQS2340
 2341 NNYQNLPEQD RNLMIPDGPK PQEDGSFKRR YPRRSARARS NMFFGLTPLY GVRSYGEEDI2400
 2401 PFYSSSTGKK RGKRSAEGQV DGADDLSTSD EDDLYYYNFT RTVISSGGDE RLASHNLFRE2460
 2461 EEQCDLPKIS QLDGVDDGTE SDTSVTATSR KSSQIPKRNG KENGTENLKI DRPEDAGEKE2520
 2521 HVIKSAVGHK NEPKLDNCHS VSRVKAQGQD SLEAQLSSLE SSRRVHTSTP SDKNLLDTYN2580
 2581 TELLKSDSDN NNSDDCGNIL PSDIMDFVLK NTPSMQALGE SPESSSSELL TLGEGLGLDS2640
 2641 NREKDMGLFE VFSQQLPATE PVDSSVSSSI SAEEQFELPL ELPSDLSVLT TRSPTVPSQN2700
 2701 SSRLAVISDS GEKRVTITEK SVTSTEGDPA LLSPGVDPAP EGHMTPDHFI QGHMDADHIS2760
 2761 SPPCGSVEQG HGNNQDLTRN SSTPGLQVPV SPTVPIQNQK YVPNSTDSPG PSQISNAAVQ2820
 2821 TTPPHLKPAT EKLIVVNQNM QPLYVLQTLP NGVTQKIQLT SPVSSTPNVM ETNTSVLGPM2880
 2881 GSGLTLTTGL NPSLPPSQSL FPPASKGLLS MPHHQHLHSF PAAAQSSFPP NISSPPSGLL2940
 2941 IGVQPPPDPQ LLGSEANQRT DLTTTVTTPS SGLKKRPISR LHTRKNKKLA PSSAPSNIAP3000
 3001 SDVVSNMTLI NFTPSQLSNH PSLLDLGSLN PSSHRTVPNI IKRSKSGIMY FEQAPLLPPQ3060
 3061 SVGGTTATGA GSSTISQDTS HLTSGPVSAL ASGSSVLNVV SMQTTTTPTS STSVPGHVTL3120
 3121 ANQRLLGTPD IGSISHLLIK ASHQSLGIQD QPVALPQSSG MFPQLGTSQT PSAAAMTAAS3180
 3181 SICVLPSSQT AGMTAASPPR EAEEQYKLQR VNQLLAGKTG TLSLQRDRDP DSAPGTQPSN3240
 3241 FTQTAEAPNG VRLEQNKTLP SAKQASSTSP GSSPSSGQQS GSSSVPGPTK PKPKVKRIQL3300
 3301 PLDKGSGKKH KVSHLRTSSE AHIPHREANP APQPSVKRTP RADREQQEAA GVEQPSQKEC3360
 3361 GQPAGPATAL PEIQATQNPA NEQENAEPKA VEEEESSFSS PLMLWLQQEQ KRKESITERK3420
 3421 PKKGLVFEIS SDDGFQICAE SIEDAWKSLT DKVQEARSNA RLKQLSFAGV NGLRMLGILH3480
 3481 DAVVFLIEQL SGAKHCRNYK FRFHKPEEAN EPPLNPHGSA RAEVHLRQSA FDMFNFLASK3540
 3541 HRQPPEYNPN DEEEEEVQLK SARRATSMDL PMPMRFRHLK KTSKEAVGVY RSPIHGRGLF3600
 3601 CKRNIDAGEM VIEYAGNVIR SIQTDKREKY YDSKGIGCYM FRIDDSEVVD ATMHGNAARF3660
 3661 INHSCEPNCY SRVINIDGQK HIVIFAMRKI YRGEELTYDY KFPIEDASNK LPCNCGAKKC3720
 3721 RKFLN

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.97

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle