Protein Overview: RET_MOUSE

General Information:
Name(s) found:	RET_MOUSE [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|6644370\|gb\|AAF21033.1\|AF209436_1 c-ret proto-oncogene [Mus musculus] [NCBI NR] gi\|51338723\|sp\|P35546.2\|RET_MOUSE RecName: Full=Proto-oncogene tyrosine-protein kinase receptor ret; Short=C-ret; Flags: Precursor [NCBI NR] gi\|148667175\|gb\|EDK99591.1\| ret proto-oncogene, isoform CRA_a [Mus musculus] [NCBI NR] gi\|124256484\|ref\|NP_033076.2\| ret proto-oncogene isoform a [Mus musculus] [NCBI NR] Proto-oncogene tyrosine-protein kinase receptor Ret OS=Mus musculus GN=Ret PE=1 SV=2 [Swiss-Prot] Splice Isoform 1 of Proto-oncogene tyrosine-protein kinase receptor ret precursor [ipi.MOUSE.v3.06.fasta] c-ret proto-oncogene [Mus musculus]gi\|51338723\|sp\|P35546\|RET_MOUSE Proto-oncogene tyrosine-protein kinase receptor ret precursor (C-ret) [nrdb_11152004_Chlamydomonas] Tax_Id=10090 Splice Isoform 1 of Proto-oncogene tyrosine-protein kinase receptor ret precursor [EBI-IPI_mouse_3.17_05-10-2006_con_reversed.fasta] ret proto-oncogene isoform a [Mus musculus] [NCBI-RefSeq_mouse_na_03-19-2007_reversed.fasta] Proto-oncogene tyrosine-protein kinase receptor ret precursor (C-ret) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] ret proto-oncogene, isoform CRA_a [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] c-ret proto-oncogene [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10090 SPLICE ISOFORM 1 OF PROTO-ONCOGENE TYROSINE-PROTEIN KINASE RECEPTOR RET PRECURSOR [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Tax_Id=10090 Gene_Symbol=Ret Isoform 1 of Proto-oncogene tyrosine-protein kinase receptor ret [mouse-ipi-250309-contam.fasta] Tax_Id=10090 Gene_Symbol=Ret Isoform 1 of Proto-oncogene tyrosine-protein kinase receptor ret precursor [ipi.MOUSE_jw_12may08.contam.fasta] Tax_Id=10090 Gene_Symbol=Ret Isoform 1 of Proto-oncogene tyrosine-protein kinase receptor ret precursor ENSMUSG00000030110 IPI00463765 IPI00463766 IPI00475091 [IPIxENS.MOUSE_plus_REVERSE.fasta] proto-oncogene tyrosine-protein kinase receptor Ret isoform a [Mus musculus] [NCBI-RefSeq_mouse_na_05-17-2010_reversed.fasta] IPI:IPI00463765.1\|SWISS-PROT:P35546-1\|ENSEMBL:ENSMUSP00000032201\|REFSEQ:NP_033076 Tax_Id=10090 Gene_Symbol=Ret Isoform 1 of Proto-oncogene tyrosine-protein kinase receptor ret [ipi.MOUSE.fasta.20090209] Isoform 1 of Proto-oncogene tyrosine-protein kinase receptor Ret OS=Mus musculus GN=Ret [011711_HMR.fasta] Tax_Id=10090 Gene_Symbol=Ret Isoform 1 of Proto-oncogene tyrosine-protein kinase receptor Ret [EBI-IPI_mouse_2_08-18-2011_reversed.fasta] sp\|P35546\|RET_MOUSE Proto-oncogene tyrosine-protein kinase receptor Ret OS=Mus musculus GN=Ret PE=1 SV=2 [uniprot.sptr.mouse.20130102]
Organism:	Mus musculus
Length:	1115 amino acids
Gene Ontology:
Cellular Component:	membrane [IEA] integral to membrane [IEA]
Biological Process:	enteric nervous system development [IMP] MAPKKK cascade [IGI] neural crest cell migration [IMP] ureteric bud development [IEP][IMP] nervous system development [IMP] neuron maturation [IMP] transmembrane receptor protein tyrosine kinase signaling pathway [IGI] embryonic epithelial tube formation [IDA][IGI] auxin biosynthetic process [IEA] anatomical structure morphogenesis [TAS] homophilic cell adhesion [IEA] protein amino acid phosphorylation [IEA]
Molecular Function:	nucleotide binding [IEA] ATP binding [IEA] protein tyrosine kinase activity [IEA] protein binding [IPI] transmembrane receptor protein tyrosine kinase activity [TAS] calcium ion binding [IEA] protein kinase activity [IEA] transferase activity [IEA] kinase activity [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAKATSGAAG LGLKLILLLP LLGEAPLGLY FSRDAYWERL YVDQPAGTPL LYVHALRDAP  60
   61 GEVPSFRLGQ HLYGVYRTRL HENDWIRINE TTGLLYLNQS LDHSSWEQLS IRNGGFPLLT 120
  121 IFLQVFLGST AQREGECHWP GCTRVYFSFI NDTFPNCSSF KAQDLCIPET AVSFRVRENR 180
  181 PPGTFYHFHM LPVQFLCPNI SVKYSLLGGD SLPFRCDPDC LEVSTRWALD RELREKYVLE 240
  241 ALCIVAGPGA NKETVTLSFP VTVYDEDDSA PTFSGGVGTA SAVVEFKRKE GTVVATLQVF 300
  301 DADVVPASGE LVRRYTNTLL SGDSWAQQTF RVEHSPIETL VQVNNNSVRA TMHNYKLILN 360
  361 RSLSISESRV LQLAVLVNDS DFQGPGAGGI LVLHFNVSVL PVTLNLPRAY SFPVNKRARR 420
  421 YAQIGKVCVE NCQEFSGVSI QYKLQPSSIN CTALGVVTSP EDTSGTLFVN DTEALRRPEC 480
  481 TKLQYTVVAT DRQTRRQTQA SLVVTVEGTS ITEEVGCPKS CAVNKRRPEC EECGGLGSPT 540
  541 GRCEWRQGDG KGITRNFSTC SPSTRTCPDG HCDAVESRDA NICPQDCLRA DIVGGHERGE 600
  601 RQGIKAGYGI CNCFPDEKKC FCEPEDSQGP LCDALCRTII TAALFSLIIS ILLSIFCVCH 660
  661 HHKHGHKPPI ASAEMTFCRP AQGFPISYSS SGTRRPSLDS TENQVPVDSF KIPEDPKWEF 720
  721 PRKNLVLGKT LGEGEFGKVV KATAFRLKGR AGYTTVAVKM LKENASQSEL RDLLSEFNLL 780
  781 KQVNHPHVIK LYGACSQDGP LLLIVEYAKY GSLRGFLRDS RKIGPAYVSG GGSRNSSSLD 840
  841 HPDERVLTMG DLISFAWQIS RGMQYLAEMK LVHRDLAARN ILVAEGRKMK ISDFGLSRDV 900
  901 YEEDSYVKKS KGRIPVKWMA IESLFDHIYT TQSDVWSFGV LLWEIVTLGG NPYPGIPPER 960
  961 LFNLLKTGHR MERPDNCSEE MYRLMLQCWK QEPDKRPVFA DISKDLEKMM VKSRDYLDLA1020
 1021 ASTPSDSLLY DDGLSEEETP LVDCNNAPLP RSLPSTWIEN KLYGMSDPNW PGESPVPLTR1080
 1081 ADGTSTGFPR YANDSVYANW MVSPSAAKLM DTFDS

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: RET_MOUSE

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: