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The developmentally regulated remodeling of neuronal projections such as pruning to eliminate the extra dendrites and axons projections set up in early stages of nervous system development. The process whose specific outcome is the progression of a neuron over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. A developmental process, independent of morphogenetic (shape) change, that is required for a neuron to attain its fully functional state. The process whereby a relatively unspecialized cell acquires specialized features of a neuron. The process by which voltage-gated ion channels become localized to distinct subcellular domains in the neuron. Specific targeting, clustering, and maintenance of these channels in their respective domains are essential to achieve high conduction velocities of action potential propagation. Any process that stops, prevents or reduces the frequency, rate or extent of neuron maturation. A biological process whose specific outcome is the progression of a cell over time from an initial condition to a later condition. Any process that activates or increases the frequency, rate or extent of neuron maturation. A developmental process, independent of morphogenetic (shape) change, that is required for a cell to attain its fully functional state. Any process that modulates the frequency, rate or extent of neuron maturation, the process leading to the attainment of the full functional capacity of a neuron. This process is independent of morphogenetic change. A developmental process, independent of morphogenetic (shape) change, that is required for an anatomical structure, cell or cellular component to attain its fully functional state. The process whose specific outcome is the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate.

View Gene Ontology (GO) Term

GO TERM SUMMARY

Name: neuron maturation
Acc: GO:0042551
Aspect: Biological Process
Desc: A developmental process, independent of morphogenetic (shape) change, that is required for a neuron to attain its fully functional state.
Proteins in PDR annotated with:
   This term: 23 [Search]
   Term or descendants: 82 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0042551 - neuron maturation (interactive image map)

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