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Protein Overview: PLM1_PLAFA

General Information:
Name(s) found: PLM1_PLAFA [Swiss-Prot]
Description(s) found:
Found 13 descriptions.
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  • Plasmepsin-1 OS=Plasmodium falciparum PE=1 SV=2 [Swiss-Prot]
    • Organism: Plasmodium falciparum
    Length: 452 amino acids

    Gene Ontology:
    Cellular Component: food vacuole [TASLink to PubMed article]
    Biological Process: hemoglobin catabolic process [TASLink to PubMed article]
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MALSIKEDFS SAFAKNESAV NSSTFNNNMK TWKIQKRFQI LYVFFFLLIT GALFYYLIDN  60
   61 VLFPKNKKIN EIMNTSKHVI IGFSIENSHD RIMKTVKQHR LKNYIKESLK FFKTGLTQKP 120
  121 HLGNAGDSVT LNDVANVMYY GEAQIGDNKQ KFAFIFDTGS ANLWVPSAQC NTIGCKTKNL 180
  181 YDSNKSKTYE KDGTKVEMNY VSGTVSGFFS KDIVTIANLS FPYKFIEVTD TNGFEPAYTL 240
  241 GQFDGIVGLG WKDLSIGSVD PVVVELKNQN KIEQAVFTFY LPFDDKHKGY LTIGGIEDRF 300
  301 YEGQLTYEKL NHDLYWQVDL DLHFGNLTVE KATAIVDSGT SSITAPTEFL NKFFEGLDVV 360
  361 KIPFLPLYIT TCNNPKLPTL EFRSATNVYT LEPEYYLQQI FDFGISLCMV SIIPVDLNKN 420
  421 TFILGDPFMR KYFTVFDYDN HTVGFALAKK KL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..452] PSI-BLAST 101.0 Plasmepsin II complexed with a highly active achiral inhibitor

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • aspartic-type endopeptidase activity
    		•  7.9145950161796 bayes_pls_golite062009
  • aspartic-type peptidase activity
    		•  7.9145950161796 bayes_pls_golite062009
  • peptidase activity
    		•  5.78181196721293 bayes_pls_golite062009
  • endopeptidase activity
    		•  5.4888481808613 bayes_pls_golite062009
  • peptidase activity, acting on L-amino acid peptides
    		•  5.39972232367526 bayes_pls_golite062009
  • hydrolase activity
    		•  4.34796304893506 bayes_pls_golite062009
  • catalytic activity
    		•  1.54514410489082 bayes_pls_golite062009
  • binding
    		•  1.10054369202721 bayes_pls_golite062009
  • receptor binding
    		•  0.561225023505917 bayes_pls_golite062009
  • protein binding
    		•  0.193907750061394 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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