YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Structure Prediction Details

Protein: PLM1_PLAFA
Organism: Plasmodium falciparum
Length: 452 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



[What does the above image mean?]


[Show Ginzu Version Information]


Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PLM1_PLAFA.

Description E-value Query
Range
Subject
Range
gi|3095038 - gi|3095038|gb|AAC15794.1| plasmepsin [Plasmodium malariae]
375.0 [0..1] [450..1]
PAG1_BOVIN - Pregnancy-associated glycoprotein 1 OS=Bos taurus PE=1 SV=1
370.0 [0..73] [448..4]
gi|114637864 - gi|114637864|ref|XP_001144824.1| PREDICTED: pepsinogen 5, group I (pepsinogen A) isoform 2 [Pan trog...
370.0 [0..51] [448..48]
gi|6180007 - gi|6180007|gb|AAF05750.1|AF191336_1 pregnancy-associated glycoprotein-11 [Capra hircus]
370.0 [0..73] [448..4]
PEPA_CANLF - Pepsin A OS=Canis lupus familiaris GN=PGA PE=2 SV=1
367.0 [0..73] [448..4]
gi|118344558, gi... - gi|55771082|dbj|BAD69801.1| cathepsin D1 [Takifugu rubripes], gi|118344558|ref|NP_001072052.1| cathe...
366.0 [0..47] [449..3]

Back

Predicted Domain #1
Region A:
Residues: [1-452]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MALSIKEDFS SAFAKNESAV NSSTFNNNMK TWKIQKRFQI LYVFFFLLIT GALFYYLIDN  60
   61 VLFPKNKKIN EIMNTSKHVI IGFSIENSHD RIMKTVKQHR LKNYIKESLK FFKTGLTQKP 120
  121 HLGNAGDSVT LNDVANVMYY GEAQIGDNKQ KFAFIFDTGS ANLWVPSAQC NTIGCKTKNL 180
  181 YDSNKSKTYE KDGTKVEMNY VSGTVSGFFS KDIVTIANLS FPYKFIEVTD TNGFEPAYTL 240
  241 GQFDGIVGLG WKDLSIGSVD PVVVELKNQN KIEQAVFTFY LPFDDKHKGY LTIGGIEDRF 300
  301 YEGQLTYEKL NHDLYWQVDL DLHFGNLTVE KATAIVDSGT SSITAPTEFL NKFFEGLDVV 360
  361 KIPFLPLYIT TCNNPKLPTL EFRSATNVYT LEPEYYLQQI FDFGISLCMV SIIPVDLNKN 420
  421 TFILGDPFMR KYFTVFDYDN HTVGFALAKK KL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 101.0
Match: 2bjuA
Description: Plasmepsin II complexed with a highly active achiral inhibitor
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
aspartic-type endopeptidase activity 7.9145950161796 bayes_pls_golite062009
aspartic-type peptidase activity 7.9145950161796 bayes_pls_golite062009
peptidase activity 5.78181196721293 bayes_pls_golite062009
endopeptidase activity 5.4888481808613 bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides 5.39972232367526 bayes_pls_golite062009
hydrolase activity 4.34796304893506 bayes_pls_golite062009
catalytic activity 1.54514410489082 bayes_pls_golite062009
binding 1.10054369202721 bayes_pls_golite062009
receptor binding 0.561225023505917 bayes_pls_golite062009
protein binding 0.193907750061394 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle