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Protein Overview: PLCD1_RAT

General Information:
Name(s) found: PLCD1_RAT [Swiss-Prot]
Description(s) found:
Found 16 descriptions.
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  • 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1 OS=Rattus norvegicus GN=Plcd1 PE=1 SV=1 [Swiss-Prot]
    • Organism: Rattus norvegicus
    Length: 756 amino acids

    Gene Ontology:
    Cellular Component: membrane fraction [IDA]
    nucleus [IDA]
    mitochondrial membrane [IDA]
    cytoplasm [UNKNOWN]
    membrane raft [IDA]
    cytosol [UNKNOWN][IDA]
    Biological Process: response to hyperoxia [IEP]
    response to aluminum ion [IEP]
    G-protein coupled receptor protein signaling pathway [IDA]
    signal transduction [IEA]
    response to peptide hormone stimulus [IMP]
    regulation of cell proliferation [UNKNOWN]
    labyrinthine layer blood vessel development [UNKNOWN]
    angiogenesis [UNKNOWN]
    elevation of cytosolic calcium ion concentration involved in G-protein signaling coupled to IP3 second messenger [IMP]
    response to calcium ion [IMP]
    lipid catabolic process [IEA]
    positive regulation of norepinephrine secretion [IMP]
    response to prostaglandin F stimulus [IEP]
    response to organic nitrogen [IEP]
    positive regulation of inositol trisphosphate biosynthetic process [IMP]
    Molecular Function: phosphoinositide phospholipase C activity [IDA]
    phosphatidylinositol-4,5-bisphosphate binding [IDA]
    protein binding [IMP][IPI]
    calcium ion binding [IDA]
    GTPase activating protein binding [UNKNOWN]
    phospholipid binding [IDA]
    signal transducer activity [IEA]
    hydrolase activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDSGRDFLTL HGLQDDPDLQ ALLKGSQLLK VKSSSWRRER FYKLQEDCKT IWQESRKVMR  60
   61 SPESQLFSIE DIQEVRMGHR TEGLEKFARD IPEDRCFSIV FKDQRNTLDL IAPSPADAQH 120
  121 WVQGLRKIIH HSGSMDQRQK LQHWIHSCLR KADKNKDNKM NFKELKDFLK ELNIQVDDGY 180
  181 ARKIFRECDH SQTDSLEDEE IETFYKMLTQ RAEIDRAFEE AAGSAETLSV ERLVTFLQHQ 240
  241 QREEEAGPAL ALSLIERYEP SETAKAQRQM TKDGFLMYLL SADGNAFSLA HRRVYQDMDQ 300
  301 PLSHYLVSSS HNTYLLEDQL TGPSSTEAYI RALCKGCRCL ELDCWDGPNQ EPIIYHGYTF 360
  361 TSKILFCDVL RAIRDYAFKA SPYPVILSLE NHCSLEQQRV MARHLRAILG PILLDQPLDG 420
  421 VTTSLPSPEQ LKGKILLKGK KLGGLLPAGG ENGSEATDVS DEVEAAEMED EAVRSQVQHK 480
  481 PKEDKLKLVP ELSDMIIYCK SVHFGGFSSP GTSGQAFYEM ASFSESRALR LLQESGNGFV 540
  541 RHNVSCLSRI YPAGWRTDSS NYSPVEMWNG GCQIVALNFQ TPGPEMDVYL GCFQDNGGCG 600
  601 YVLKPAFLRD PNTTFNSRAL TQGPWWRPER LRVRIISGQQ LPKVNKNKNS IVDPKVIVEI 660
  661 HGVGRDTGSR QTAVITNNGF NPRWDMEFEF EVTVPDLALV RFMVEDYDSS SKNDFIGQST 720
  721 IPWNSLKQGY RHVHLLSKNG DQHPSATLFV KISIQD

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle