Protein Overview: FBpp0311922, NetA-PA

General Information:
Name(s) found:	FBpp0311922 [FlyBase] NetA-PA / FBpp0073759 [FlyBase]
Description(s) found: SHOW ONLY BEST	gi\|51704316\|sp\|Q24567.2\|NETA_DROME RecName: Full=Netrin-A; Flags: Precursor [NCBI NR] gi\|45549129\|ref\|NP_511154.3\| Netrin-A [Drosophila melanogaster] [NCBI NR] gi\|45446952\|gb\|AAF48380.3\| Netrin-A [Drosophila melanogaster] [NCBI NR] Netrin-A OS=Drosophila melanogaster GN=NetA PE=2 SV=2 [Swiss-Prot] type=protein; loc=X:complement(14498519..14498660,14498779..14499157,14500516..14500581,14504472..14504624,14504694..14504843,14514733..14514921,14546176..14547277); ID=FBpp0311922; name=NetA-PC; parent=FBgn0015773,FBtr0346088; dbxref=FlyBase:FBpp0311922,FlyBase_Annotation_IDs:CG18657-PC; MD5=f81b86e41da59643d91013f195ccbfd6; length=726; release=r5.56; species=Dmel; [FlyBase] The gene Netrin-A is referred to in FlyBase by the symbol Dmel\NetA (CG18657, FBgn0015773). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:14498045..14547864. It has the cytological map location 12F1-12F2. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: protein binding. There is experimental evidence that it is involved in the biological process</span>: motor axon guidance; dendrite guidance. 14 alleles are reported. The phenotypes of these alleles are annotated with: commissure; optic nerve; intersegmental nerve; lamina; transverse nerve; axon. It has one annotated transcript and one annotated polypeptide. [FlyBase] (AAF48380) CG18657-PA [DrosMelano7227.FASTAC.txt] CG18657-PA [Drosophila melanogaster]gi\|45549129\|ref\|NP_511154.3\| CG18657-PA [Drosophila melanogaster]gi\|51704316\|sp\|Q24567\|NETA_DROME Netrin-A precursor [nrdb_11152004_Chlamydomonas] type=protein; loc=X:complement(14498519..14498660,14498779..14499157,14500516..14500581,14504472..14504624,14504694..14504843,14514733..14514921,14546176..14547277); ID=FBpp0073759; name=NetA-PA; parent=FBgn0015773,FBtr0073942; dbxref=FlyBase_Annotation_I [fly-100309-contam.fasta] Netrin-A precursor [nr-271106-contam.fasta] CG18657-PA [Drosophila melanogaster] [nr-271106-contam.fasta] Netrin-A CG18657-PA [Drosophila melanogaster] [nr-271106-contam.fasta] type=protein; loc=X:complement(14498519..14498660,14498779..14499157,14500516..14500581,14504472..14504624,14504694..14504843,14514733..14514921,14546176..14547277); ID=FBpp0073759; name=NetA-PA; parent=FBgn0015773,FBtr0073942; dbxref=FlyBase_Annotation_IDs:CG18657-PA,FlyBase:FBpp0073759,GB_protein:AAF48380.3,REFSEQ:NP_511154,GB_protein:AAF48380; MD5=f81b86e41da59643d91013f195ccbfd6; length=726; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta] type=protein; loc=X:complement(14498519..14498660,14498779..14499157,14500516..14500581,14504472..14504624,14504694..14504843,14514733..14514921,14546176..14547277); ID=FBpp0073759; name=NetA-PA; parent=FBgn0015773,FBtr0073942; dbxref=FlyBase_Annotation_IDs:CG18657-PA,FlyBase:FBpp0073759,GB_protein:AAF48380.3,REFSEQ:NP_511154,GB_protein:AAF48380; MD5=f81b86e41da59643d91013f195ccbfd6; length=726; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta] Netrin-A OS=Drosophila melanogaster GN=NetA PE=1 SV=2 [UniProt_drosophila_07-01-2011_reversed.fasta] type=protein; loc=X:complement(14498519..14498660,14498779..14499157,14500516..14500581,14504472..14504624,14504694..14504843,14514733..14514921,14546176..14547277); ID=FBpp0073759; name=NetA-PA; parent=FBgn0015773,FBtr0073942; dbxref=FlyBase_Annotation_IDs:CG18657-PA,FlyBase:FBpp0073759,GB_protein:AAF48380.3,REFSEQ:NP_511154,GB_protein:AAF48380,FlyMine:FBpp0073759,modMine:FBpp0073759; MD5=f81b86e41da59643d91013f195ccbfd6; length=726; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta] type=protein; loc=X:complement(join(14652143..14653244,14620700..14620888,14610661..14610810,14610439..14610591,14606483..14606548,14604746..14605124,14604486..14604627)); ID=FBpp0073759; name=NetA-PA; parent=FBgn0015773,FBtr0073942; dbxref=FlyBase_Annotation_IDs:CG18657-PA,FlyBase:FBpp0073759,GB_protein:AAF48380.3,REFSEQ:NP_511154,GB_protein:AAF48380,FlyMine:FBpp0073759,modMine:FBpp0073759; MD5=f81b86e41da59643d91013f195ccbfd6; length=726; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta] type=protein; loc=X:complement(join(14652143..14653244,14620700..14620888,14610661..14610810,14610439..14610591,14606483..14606548,14604746..14605124,14604486..14604627)); ID=FBpp0311922; name=NetA-PC; parent=FBgn0015773,FBtr0346088; dbxref=FlyBase:FBpp0311922,FlyBase_Annotation_IDs:CG18657-PC,GB_protein:AHN59713,REFSEQ:NP_001285243; MD5=f81b86e41da59643d91013f195ccbfd6; length=726; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta] type=protein; loc=X:complement(join(14652143..14653244,14620700..14620888,14610661..14610810,14610439..14610591,14606483..14606548,14604746..14605124,14604486..14604627)); ID=FBpp0073759; name=NetA-PA; parent=FBgn0015773,FBtr0073942; dbxref=FlyBase_Annotation_IDs:CG18657-PA,FlyBase:FBpp0073759,GB_protein:AAF48380.3,REFSEQ:NP_511154,GB_protein:AAF48380,FlyMine:FBpp0073759,modMine:FBpp0073759; MD5=f81b86e41da59643d91013f195ccbfd6; length=726; release=r6.07; species=Dmel; [fly-08202015-contam.fasta] type=protein; loc=X:complement(join(14652143..14653244,14620700..14620888,14610661..14610810,14610439..14610591,14606483..14606548,14604746..14605124,14604486..14604627)); ID=FBpp0311922; name=NetA-PC; parent=FBgn0015773,FBtr0346088; dbxref=FlyBase:FBpp0311922,FlyBase_Annotation_IDs:CG18657-PC,GB_protein:AHN59713,REFSEQ:NP_001285243; MD5=f81b86e41da59643d91013f195ccbfd6; length=726; release=r6.07; species=Dmel; [fly-08202015-contam.fasta] Isoform of Q24567, Netrin-A, isoform C OS=Drosophila melanogaster GN=NetA PE=4 SV=1 [DROME.fasta.20160308] FBpp0073759 type=protein; loc=X:complement(join(14652143..14653244,14620700..14620888,14610661..14610810,14610439..14610591,14606483..14606548,14604746..14605124,14604486..14604627)); ID=FBpp0073759; name=NetA-PA; parent=FBgn0015773,FBtr0073942; dbxref=FlyBase_Annotation_IDs:CG18657-PA,FlyBase:FBpp0073759,GB_protein:AAF48380.3,REFSEQ:NP_511154,GB_protein:AAF48380,FlyMine:FBpp0073759,modMine:FBpp0073759; MD5=f81b86e41da59643d91013f195ccbfd6; length=726; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta] FBpp0311922 type=protein; loc=X:complement(join(14652143..14653244,14620700..14620888,14610661..14610810,14610439..14610591,14606483..14606548,14604746..14605124,14604486..14604627)); ID=FBpp0311922; name=NetA-PC; parent=FBgn0015773,FBtr0346088; dbxref=FlyBase:FBpp0311922,FlyBase_Annotation_IDs:CG18657-PC,GB_protein:AHN59713,REFSEQ:NP_001285243; MD5=f81b86e41da59643d91013f195ccbfd6; length=726; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta] [fly-122215-dmel-6-09-contam.fasta] type=protein; loc=X:complement(join(14652143..14653244,14620700..14620888,14610661..14610810,14610439..14610591,14606483..14606548,14604746..14605124,14604486..14604627)); ID=FBpp0073759; name=NetA-PA; parent=FBgn0015773,FBtr0073942; dbxref=FlyBase_Annotation_IDs:CG18657-PA,FlyBase:FBpp0073759,GB_protein:AAF48380.3,REFSEQ:NP_511154,GB_protein:AAF48380,UniProt/Swiss-Prot:Q24567,FlyMine:FBpp0073759,modMine:FBpp0073759; MD5=f81b86e41da59643d91013f195ccbfd6; length=726; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta] type=protein; loc=X:complement(join(14652143..14653244,14620700..14620888,14610661..14610810,14610439..14610591,14606483..14606548,14604746..14605124,14604486..14604627)); ID=FBpp0311922; name=NetA-PC; parent=FBgn0015773,FBtr0346088; dbxref=FlyBase:FBpp0311922,FlyBase_Annotation_IDs:CG18657-PC,GB_protein:AHN59713,REFSEQ:NP_001285243,UniProt/Swiss-Prot:Q24567; MD5=f81b86e41da59643d91013f195ccbfd6; length=726; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
Organism:	Drosophila melanogaster
Length:	726 amino acids
Gene Ontology:
Cellular Component:	extracellular region [ISS] proteinaceous extracellular matrix [ISS]
Biological Process:	motor axon guidance [IMP] axon guidance [ISS][NAS] dendrite guidance [IGI]
Molecular Function:	protein binding [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIRGILLLLL GTTRFSPIQC ISNDVYFKMF SQQAPPEDPC YNKAHEPRAC IPDFVNAAYD  60
   61 APVVASSTCG SSGAQRYCEY QDHERSCHTC DMTDPLRSFP ARSLTDLNNS NNVTCWRSEP 120
  121 VTGSGDNVTL TLSLGKKFEL TYVILQLCPH APRPDSMVIY KSTDHGLSWQ PFQFFSSQCR 180
  181 RLFGRPARQS TGRHNEHEAR CSDVTRPLVS RIAFSTLEGR PSSRDLDSSP VLQDWVTATD 240
  241 IRVVFHRLQR PDPQALLSLE AGGATDLASG KYSVPLANGP AGNNIEANLG GDVATSGSGL 300
  301 HYAISDFSVG GRCKCNGHAS KCSTDASGQL NCECSHNTAG RDCERCKPFH FDRPWARATA 360
  361 KEANECKECN CNKHARQCRF NMEIFRLSQG VSGGVCQNCR HSTTGRNCHQ CKEGFYRDAT 420
  421 KPLTHRKVCK ACDCHPIGSS GKICNSTSGQ CPCKDGVTGL TCNRCARGYQ QSRSHIAPCI 480
  481 KQPPRMINML DTQNTAPEPD EPESSPGSGG DRNGAAGMAA QSQYYRTEGG RECGKCRVST 540
  541 KRLNLNKFCK RDYAIMAKVI GRDTSSEAVS REVQRRAMDP DVADYEMDQV QPGSARSPIT 600
  601 GVYEFQAADY PNPNPNPRGS EMERFDLQIQ AVFKRSRPGE SSGAGNVYGM PNTTLKRGPM 660
  661 TWIIPTKDLE CRCPRIRVNR SYLILGRDSE APPGYLGIGP HSIVIEWKED WYRRMKRFQR 720
  721 RARTCA

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..262]	FFAS03	1.47	No description for 2jd9A was found.
2	View Details	[263..650]	PSI-BLAST	9.0	Low density lipoprotein (LDL) receptor YWTD domain; Low density lipoprotein (LDL) receptor, different EGF domains; Ligand-binding domain of low-density lipoprotein receptor
3	View Details	[651..726]	FFAS03	3.58	Procollagen c-proteinase enhancer protein PCOLCE

Protein Overview: FBpp0311922, NetA-PA

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: