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Protein Overview: mec-1

General Information:
Name(s) found: mec-1 / CE41017 [WormBase]
Description(s) found:
Found 9 descriptions.
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  • WBGene00003165 locus:mec-1 status:Confirmed UniProt:A5A8R2 protein_id:CCD66564.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 255 amino acids

    Gene Ontology:
    Cellular Component: extracellular region [IEALink to PubMed article]
    Biological Process: mechanosensory behavior [IMPLink to PubMed article]
    extracellular structure organization [IMPLink to PubMed article]
    blood coagulation [IEALink to PubMed article]
    response to mechanical stimulus [IMPLink to PubMed article]
    Molecular Function: peptidase inhibitor activity [IEALink to PubMed article]
    serine-type endopeptidase inhibitor activity [IEALink to PubMed article]
    calcium ion binding [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MHLFLLFIPH VIAVKDLAWY SANPVLSSSH LVGPAAIQAA TRIDFCQLPV DTGKCSQQLV  60
   61 RYYYDAAVDE CKRFTFSGCG GNSNRFMRRA HCRNRCVKQP NKPEVQELKH RRTVTSTTST 120
  121 PFQTVNEEST VEPSATKRLP VTLPVKKLEL VQSGHGNGLC QDCDPLYGTC LDGKCGCMKG 180
  181 FRSLGKVCID LNECDNGAVC GPNARCVNEI GSFQCVCDAG FSTDGDCKIG QEACMDEFDV 240
  241 NLTEEDCNNG KQEIK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..255] PSI-BLAST 11.69897 Low density lipoprotein (LDL) receptor YWTD domain; Low density lipoprotein (LDL) receptor, different EGF domains; Ligand-binding domain of low-density lipoprotein receptor


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.83

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle