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Protein Overview: MG15_MOUSE

General Information:
Name(s) found: MG15_MOUSE [Swiss-Prot]
Description(s) found:
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  • gi|82964926|ref|XP_920861.1| PREDICTED: similar to HSPC008 isoform 1 [Mus musculus] [NCBI NR]
  • gi|82959128|ref|XP_898862.1| PREDICTED: similar to HSPC008 isoform 1 [Mus musculus] [NCBI NR]
  • gi|74355081|gb|AAI03784.1| Mortality factor 4 like 1 [Mus musculus] [NCBI NR]
  • gi|74226656|dbj|BAE26980.1| unnamed protein product [Mus musculus] [NCBI NR]
  • gi|74219880|dbj|BAE40524.1| unnamed protein product [Mus musculus] [NCBI NR]
  • gi|74219765|dbj|BAE40475.1| unnamed protein product [Mus musculus] [NCBI NR]
  • gi|74214438|dbj|BAE40454.1| unnamed protein product [Mus musculus] [NCBI NR]
  • gi|74212214|dbj|BAE40266.1| unnamed protein product [Mus musculus] [NCBI NR]
  • gi|74188934|dbj|BAE39239.1| unnamed protein product [Mus musculus] [NCBI NR]
  • gi|74139422|dbj|BAE40852.1| unnamed protein product [Mus musculus] [NCBI NR]
  • gi|62185712|gb|AAH92293.1| Mortality factor 4 like 1 [Mus musculus] [NCBI NR]
  • gi|52789305|gb|AAH83118.1| Mortality factor 4 like 1 [Mus musculus] [NCBI NR]
  • sp|P60762|MG15_MOUSE Transcription factor-like protein MRG15 (MORF-related gene 15 protein) (Mortality factor 4-like 1) [NCBI NR]
  • gi|17160904|gb|AAH17619.1| Mortality factor 4 like 1 [Mus musculus] [NCBI NR]
  • gi|148688957|gb|EDL20904.1| mCG7766, isoform CRA_c [Mus musculus] [NCBI NR]
  • gi|148665262|gb|EDK97678.1| mCG125079 [Mus musculus] [NCBI NR]
  • gi|14275916|dbj|BAB58904.1| MRG15 [Mus musculus] [NCBI NR]
  • gi|13278084|gb|AAH03894.1| Mortality factor 4 like 1 [Mus musculus] [NCBI NR]
  • gi|13277348|ref|NP_077751.1| mortality factor 4 like 1 isoform b [Mus musculus] [NCBI NR]
  • gi|12855127|dbj|BAB30219.1| unnamed protein product [Mus musculus] [NCBI NR]
  • gi|12746237|gb|AAK07406.1|AF319620_1 histone acetylase complex subunit MRG15-1 [Mus musculus] [NCBI NR]
  • (P60762) Transcription factor-like protein MRG15 (MORF-related gene 15 protein) (Mortality factor 4-like 1) [Swiss-Prot]
  • mortality factor 4 like 1; testis expressed gene 189 [HMR_022704-rand.fasta]
  • Splice Isoform 2 of Mortality factor 4-like protein 1 [ipi.MOUSE.v3.06.fasta]
  • MORF-related gene 15 isoform 1 [Homo sapiens]gi|13277348|ref|NP_077751.1| mortality factor 4 like 1 [Mus musculus]gi|52789305|gb|AAH83118.1| Mortality factor 4 like 1 [Mus musculus]gi|54035370|gb|AAH84008.1| Unknown (protein for MGC:98166) [Xenopus lae [nrdb_11152004_Chlamydomonas]
  • Tax_Id=10090 Splice Isoform 2 of Mortality factor 4-like protein 1 [EBI-IPI_mouse_3.17_05-10-2006_con_reversed.fasta]
  • (NM_024431) testis expressed gene 189 [Mus musculus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta]
  • mortality factor 4 like 1 [Mus musculus] [mouse-NCBI-010306_contam_rand.fasta]
  • PREDICTED: similar to mortality factor 4 like 1 isoform 1 [Mus musculus] [mouse-NCBI-010306_contam_rand.fasta]
  • mortality factor 4 like 1 isoform b [Mus musculus] [NCBI-RefSeq_mouse_na_03-19-2007_reversed.fasta]
  • PREDICTED: similar to mortality factor 4 like 1 isoform b isoform 1 [Mus musculus] [NCBI-RefSeq_mouse_na_03-19-2007_reversed.fasta]
  • PREDICTED: similar to HSPC008 isoform 1 [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • mCG7766, isoform CRA_c [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • mCG125079 [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • unnamed protein product [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • Mortality factor 4 like 1 [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • MRG15 [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • histone acetylase complex subunit MRG15-1 [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • Tax_Id=10090 TRANSCRIPTION FACTOR-LIKE PROTEIN MRG15 [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta]
  • Tax_Id=10090 Gene_Symbol=A730098P11Rik;Morf4l1 Isoform 2 of Mortality factor 4-like protein 1 [mouse-ipi-250309-contam.fasta]
  • Tax_Id=10090 Gene_Symbol=Morf4l1;A730098P11Rik Isoform 2 of Mortality factor 4-like protein 1 [ipi.MOUSE_jw_12may08.contam.fasta]
  • mortality factor 4-like protein 1 isoform b [Mus musculus] [NCBI-RefSeq_mouse_na_05-17-2010_reversed.fasta]
  • IPI:IPI00553815.1|SWISS-PROT:P60762-2|TREMBL:Q3U5J6;Q3UBK1;Q3UIS6;Q569V4;Q5DTS9;Q8CIW3|REFSEQ:NP_077751;XP_898862;XP_920861 Tax_Id=10090 Gene_Symbol=Morf4l1;A730098P11Rik Isoform 2 of Mortality factor 4-like protein 1 [ipi.MOUSE.fasta.20090209]
  • Isoform 2 of Mortality factor 4-like protein 1 OS=Mus musculus GN=Morf4l1 [011711_HMR.fasta]
  • Tax_Id=10090 Gene_Symbol=Morf4l1;Gm6747 Isoform 2 of Mortality factor 4-like protein 1 [EBI-IPI_mouse_2_08-18-2011_reversed.fasta]
  • tr|Q569V4|Q569V4_MOUSE MCG125079 OS=Mus musculus GN=Morf4l1 PE=2 SV=1 [uniprot.sptr.mouse.20130102]
  • MCG125079 OS=Mus musculus GN=Morf4l1 PE=2 SV=1 [mouse-uniprot-290313-contam.fasta]
  • Isoform of P60762, Isoform 2 of Mortality factor 4-like protein 1 OS=Mus musculus GN=Morf4l1 [MOUSE.fasta.20160308]
    • Organism: Mus musculus
    Length: 323 amino acids

    Gene Ontology:
    Cellular Component: cellular_component [ND]
    Biological Process: biological_process [ND]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAPKQDPKPK FQEGERVLCF HGPLLYEAKC VKVAIKDKQV KYFIHYSGWN KNWDEWVPES  60
   61 RVLKYVDTNL QKQRELQKAN QEQYAEGKMR GAAPGKKTSG LQQKNVEVKT KKNKQKTPGN 120
  121 GDGGSTSETP QPPRKKRARV DPTVENEETF MNRVEVKVKI PEELKPWLVD DWDLITRQKQ 180
  181 LFYLPAKKNV DSILEDYANY KKSRGNTDNK EYAVNEVVAG IKEYFNVMLG TQLLYKFERP 240
  241 QYAEILADHP DAPMSQVYGA PHLLRLFVRI GAMLAYTPLD EKSLALLLNY LHDFLKYLAK 300
  301 NSATLFSASD YEVAPPEYHR KAV

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..139] PSI-BLAST 29.154902 No description for 2efiA was found.
    2 View Details [140..323] PSI-BLAST 69.0 Crystal Structure of the MRG15 MRG domain

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • transcription repressor activity
    		•  4.08500855631983 bayes_pls_golite062009
  • chromatin binding
    		•  3.84065302930105 bayes_pls_golite062009
  • transcription regulator activity
    		•  3.64390820819794 bayes_pls_golite062009
  • methylated histone residue binding
    		•  3.42338304360938 bayes_pls_golite062009
  • binding
    		•  3.06758476214113 bayes_pls_golite062009
  • protein binding
    		•  2.66728689880621 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.19167058827256 bayes_pls_golite062009
  • DNA binding
    		•  2.05514577638135 bayes_pls_golite062009
  • histone binding
    		•  2.00388175060339 bayes_pls_golite062009
  • satellite DNA binding
    		•  1.4681464542396 bayes_pls_golite062009
  • transcription activator activity
    		•  1.46529895769882 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  1.10020047862576 bayes_pls_golite062009
  • DNA-dependent ATPase activity
    		•  0.998957812785999 bayes_pls_golite062009
  • general transcriptional repressor activity
    		•  0.75184432495983 bayes_pls_golite062009
  • DNA helicase activity
    		•  0.726970683178132 bayes_pls_golite062009
  • ATP-dependent DNA helicase activity
    		•  0.494788451379878 bayes_pls_golite062009
  • transcription corepressor activity
    		•  0.294457188332415 bayes_pls_golite062009
  • catalytic activity
    		•  0.14067200158938 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle