Protein Overview: AGO2_RAT

General Information:
Name(s) found:	AGO2_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|38372868\|sp\|Q9QZ81.2\|AGO2_RAT RecName: Full=Protein argonaute-2; AltName: Full=Argonaute2; AltName: Full=Protein slicer; AltName: Full=Eukaryotic translation initiation factor 2C 2; Short=eIF-2C 2; Short=eIF2C 2; AltName: Full=Golgi ER protein 95 kDa; [NCBI NR] Eukaryotic translation initiation factor 2C 2 OS=Rattus norvegicus GN=Eif2c2 PE=2 SV=2 [Swiss-Prot] Protein argonaute-2 OS=Rattus norvegicus GN=Ago2 PE=2 SV=2 [Swiss-Prot] Eukaryotic translation initiation factor 2C 2 (eIF2C 2) (eIF-2C 2) (Golgi ER protein 95 kDa) (GERp95) [nrdb_11152004_Chlamydomonas] Eukaryotic translation initiation factor 2C 2 (eIF2C 2) (eIF-2C 2) (Argonaute-2) (Golgi ER protein 95 kDa) (GERp95) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Protein argonaute-2 OS=Rattus norvegicus GN=Eif2c2 [011711_HMR.fasta] Protein argonaute-2 OS=Rattus norvegicus GN=Eif2c2 PE=2 SV=2 [UNIPROT_RAT_07-21-2011_reversed.fasta]
Organism:	Rattus norvegicus
Length:	860 amino acids
Gene Ontology:
Cellular Component:	nucleus [IEA] micro-ribonucleoprotein complex [UNKNOWN][ISS] mRNA cap binding complex [UNKNOWN][ISS] cytoplasm [IEA] cytoplasmic mRNA processing body [IEA] RNA-induced silencing complex [UNKNOWN][ISS]
Biological Process:	regulation of translation [IEA] negative regulation of translation involved in gene silencing by miRNA [UNKNOWN][ISS] negative regulation of translational initiation [UNKNOWN][ISS] pre-microRNA processing [UNKNOWN][ISS] cell differentiation [NAS] gene silencing by RNA [IEA] mRNA cleavage involved in gene silencing by miRNA [UNKNOWN][ISS] regulation of transcription [IEA]
Molecular Function:	RNA 7-methylguanosine cap binding [UNKNOWN][ISS] protein binding [UNKNOWN][IEA] endoribonuclease activity, cleaving siRNA-paired mRNA [UNKNOWN][ISS] metal ion binding [IEA] endonuclease activity [IEA] siRNA binding [UNKNOWN][ISS] hydrolase activity [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MYSGAGPVLA SPAPTTSPIP GYAFKPPPRP DFGTTGRTIK LQANFFEMDI PKIDIYHYEL  60
   61 DIKPEKCPRR VNREIVEHMV QHFKTQIFGD RKPVFDGRKN LYTAMPLPIG RDKVELEVTL 120
  121 PGEGKDRIFK VSIKWVSCVS LQALHDALSG RLPSVPFETI QALDVVMRHL PSMRYTPVGR 180
  181 SFFTASEGCS NPLGGGREVW FGFHQSVRPS LWKMMLNIDV SATAFYKAQP VIEFVCEVLD 240
  241 FKSIEEQQKP LTDSQRVKFT KEIKGLKVEI THCGQMKRKY RVCNVTRRPA SHQTFPLQQE 300
  301 SGQTVECTVA QYFKDRHKLV LRYPHLPCLQ VGQEQKHTYL PLEVCNIVAG QRCIKKLTDN 360
  361 QTSTMIRATA RSAPDRQEEI SKLMRSASFN TDPYVREFGI MVKDEMTDVT GRVLQPPSIL 420
  421 YGGRNKAIAT PVQGVWDMRN KQFHTGIEIK VWAIACFAPQ RQCTEVHLKS FTEQLRKISR 480
  481 DAGMPIQGQP CFCKYAQGAD SVEPMFRHLK NTYAGLQLVV VILPGKTPVY AEVKRVGDTV 540
  541 LGMATQCVQM KNVQRTTPQT LSNLCLKINV KLGGVNNILL PQGRPPVFQQ PVIFLGADVT 600
  601 HPPAGDGKKP SIAAVVGSMD AHPNRYCATV RVQQHRQEII QDLAAMVREL LIQFYKSTRF 660
  661 KPTRIIFYRD GVSEGQFQQV LHHELLAIRE ACIKLEKEYQ PGITFIVVQK RHHTRLFCTD 720
  721 KNERVGKSGN IPAGTTVDTK ITHPTEFDFY LCSHAGIQGT SRPSHYHVLW DDNRFSSDEL 780
  781 QILTYQLCHT YVRCTRSVSI PAPAYYAHLV AFRARYHLVD KEHDSAEGSH TSGQSNGRDH 840
  841 QALAKAVQVH QDTLRTMYFA

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.63

Protein Overview: AGO2_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: