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Protein Overview: GSHB_ECOLI

General Information:
Name(s) found: GSHB_ECOLI [Swiss-Prot]
Description(s) found:
Found 18 descriptions.
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  • Glutathione synthetase (EC 6.3.2.3) (Glutathione synthase) (GSH synthetase) (GSH-S) (GSHase) - Escherichia coli [Swiss-Prot]
    • Organism: Escherichia coli
    Length: 316 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIKLGIVMDP IANINIKKDS SFAMLLEAQR RGYELHYMEM GDLYLINGEA RAHTRTLNVK  60
   61 QNYEEWFSFV GEQDLPLADL DVILMRKDPP FDTEFIYATY ILERAEEKGT LIVNKPQSLR 120
  121 DCNEKLFTAW FSDLTPETLV TRNKAQLKAF WEKHSDIILK PLDGMGGASI FRVKEGDPNL 180
  181 GVIAETLTEH GTRYCMAQNY LPAIKDGDKR VLVVDGEPVP YCLARIPQGG ETRGNLAAGG 240
  241 RGEPRPLTES DWKIARQIGP TLKEKGLIFV GLDIIGDRLT EINVTSPTCI REIEAEFPVS 300
  301 ITGMLMDAIE ARLQQQ

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..316] PSI-BLAST 75.69897 STRUCTURE OF GLUTATHIONE SYNTHETASE COMPLEXED WITH ADP AND GLUTATHIONE

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • glutathione synthase activity
    		•  3.18460876432532 bayes_pls_golite062009
  • catalytic activity
    		•  2.5009559386228 bayes_pls_golite062009
  • glutathione binding
    		•  2.38364045371863 bayes_pls_golite062009
  • ligase activity
    		•  2.15409885945916 bayes_pls_golite062009
  • succinate-CoA ligase activity
    		•  1.52785506428706 bayes_pls_golite062009
  • ligase activity, forming carbon-sulfur bonds
    		•  0.935432886482705 bayes_pls_golite062009
  • acid-amino acid ligase activity
    		•  0.599203164789408 bayes_pls_golite062009
  • CoA-ligase activity
    		•  0.51228075142462 bayes_pls_golite062009
  • acid-thiol ligase activity
    		•  0.448084116680826 bayes_pls_golite062009
  • ligase activity, forming carbon-carbon bonds
    		•  0.351267830197198 bayes_pls_golite062009
  • succinate-CoA ligase (ADP-forming) activity
    		•  0.324506681366243 bayes_pls_golite062009
  • ligase activity, forming carbon-nitrogen bonds
    		•  0.239594107637156 bayes_pls_golite062009
  • CoA carboxylase activity
    		•  0.185924207432397 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle