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Protein Overview: ARBK1_MOUSE

General Information:
Name(s) found: ARBK1_MOUSE [Swiss-Prot]
Description(s) found:
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  • gi|74212870|dbj|BAE33390.1| unnamed protein product [Mus musculus] [NCBI NR]
  • gi|47605537|sp|Q99MK8.2|ARBK1_MOUSE RecName: Full=Beta-adrenergic receptor kinase 1; Short=Beta-ARK-1; AltName: Full=G-protein-coupled receptor kinase 2 [NCBI NR]
  • (Q99MK8) Beta-adrenergic receptor kinase 1 (EC 2.7.1.126) (Beta-ARK-1) (G-protein coupled receptor kinase 2) [Swiss-Prot]
  • Beta-adrenergic receptor kinase 1 OS=Mus musculus GN=Adrbk1 PE=1 SV=2 [Swiss-Prot]
  • Beta-adrenergic receptor kinase 1 (Beta-ARK-1) (G-protein coupled receptor kinase 2) [nrdb_11152004_Chlamydomonas]
  • Beta-adrenergic receptor kinase 1 [ipi.MOUSE.v3.06.fasta]
  • Tax_Id=10090 Beta-adrenergic receptor kinase 1 [EBI-IPI_mouse_3.17_05-10-2006_con_reversed.fasta]
  • Beta-adrenergic receptor kinase 1 (Beta-ARK-1) (G-protein-coupled receptor kinase 2) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • unnamed protein product [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • Tax_Id=10090 BETA-ADRENERGIC RECEPTOR KINASE 1 [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta]
  • Tax_Id=10090 Gene_Symbol=Adrbk1 Beta-adrenergic receptor kinase 1 [mouse-ipi-250309-contam.fasta]
  • Tax_Id=10090 Gene_Symbol=Adrbk1 Beta-adrenergic receptor kinase 1 ENSMUSG00000024858 IPI00469231 IPI00320687 [IPIxENS.MOUSE_plus_REVERSE.fasta]
  • IPI:IPI00320687.2|SWISS-PROT:Q99MK8|TREMBL:Q3U1V3|ENSEMBL:ENSMUSP00000086114 Tax_Id=10090 Gene_Symbol=Adrbk1 Beta-adrenergic receptor kinase 1 [ipi.MOUSE.fasta.20090209]
  • Beta-adrenergic receptor kinase 1 OS=Mus musculus GN=Adrbk1 [011711_HMR.fasta]
  • Beta-adrenergic receptor kinase 1 OS=Mus musculus GN=Adrbk1 PE=2 SV=2 [UniProt_mouse_sprotvarsplic_11-08-2010_reversed.fasta]
  • sp|Q99MK8|ARBK1_MOUSE Beta-adrenergic receptor kinase 1 OS=Mus musculus GN=Adrbk1 PE=2 SV=2 [uniprot.sptr.mouse.20130102]
  • tr|Q3U1V3|Q3U1V3_MOUSE Putative uncharacterized protein OS=Mus musculus GN=Adrbk1 PE=2 SV=1 [uniprot.sptr.mouse.20130102]
  • Putative uncharacterized protein OS=Mus musculus GN=Adrbk1 PE=2 SV=1 [mouse-uniprot-290313-contam.fasta]
  • Isoform of Q99MK8, Beta-adrenergic receptor kinase 1 OS=Mus musculus GN=Adrbk1 PE=1 SV=1 [MOUSE.fasta.20160308]
    • Organism: Mus musculus
    Length: 689 amino acids

    Gene Ontology:
    Cellular Component: membrane fraction [UNKNOWN]
    caveola [UNKNOWN]
    dendritic shaft [UNKNOWN]
    membrane [IDA]
    dendritic spine [UNKNOWN]
    synapse [UNKNOWN]
    axon [UNKNOWN]
    Biological Process: regulation of the force of heart contraction [IGI]
    response to oxidative stress [UNKNOWN]
    heart development [IMP]
    desensitization of G-protein coupled receptor protein signaling pathway [IGI][IMP]
    G-protein coupled receptor protein signaling pathway [UNKNOWN][IDA]
    signal transduction [IEA]
    auxin biosynthetic process [IEA]
    response to organic cyclic substance [UNKNOWN]
    phosphorylation [IEA]
    peptidyl-serine phosphorylation [IDA]
    protein amino acid phosphorylation [UNKNOWN][IDA]
    peptidyl-threonine phosphorylation [IDA]
    Molecular Function: nucleotide binding [IEA]
    ATP binding [IEA]
    protein binding [IPI]
    beta-adrenergic receptor kinase activity [IEA]
    G-protein coupled receptor kinase activity [IDA][IMP]
    protein kinase activity [IDA]
    protein serine/threonine kinase activity [IDA]
    transferase activity [IEA]
    receptor activity [IEA]
    kinase activity [IEA]
    signal transducer activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MADLEAVLAD VSYLMAMEKS KATPAARASK KILLPEPSIR SVMQKYLEDR GEVTFEKIFS  60
   61 QKLGYLLFRD FCLNHLEEAK PLVEFYEEIK KYEKLETEEE RVVRSREIFD SYIMKELLAC 120
  121 SHPFSKNATE HVQGHLVKKQ VPPDLFQPYI EEICQNLRGD VFQKFIESDK FTRFCQWKNV 180
  181 ELNIHLTMND FSVHRIIGRG GFGEVYGCRK ADTGKMYAMK CLDKKRIKMK QGETLALNER 240
  241 IMLSLVSTGD CPFIVCMSYA FHTPDKLSFI LDLMNGGDLH YHLSQHGVFS EADMRFYAAE 300
  301 IILGLEHMHN RFVVYRDLKP ANILLDEHGH VRISDLGLAC DFSKKRPHAS VGTHGYMAPE 360
  361 VLQKGVAYDS SADWFSLGCM LFKLLRGHSP FRQHKTKDKH EIDRMTLTMA VELPDSFSPE 420
  421 LRSLLEGLLQ RDVNRRLGCL GRGAQEVKES PFFRSLDWQM VFLQKYPPPL IPPRGEVNAA 480
  481 DAFDIGSFDE EDTKGIKLLD SDQELYRNFP LTISERWQQE VAETVFDTIN AETDRLEARK 540
  541 KAKNKQLGHE EDYALGKDCI VHGYMSKMGN PFLTQWQRRY FYLFPNRLEW RGEGEAPQSL 600
  601 LTMEEIQSVE ETQIKERKCL LLKIRGGKQF VLQCDSDPEL VQWKKELRDA YREAQQLVQR 660
  661 VPKMKNKPRS PVVELSKVPL IQRGSANGL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.96

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle