Protein Overview: ttn-1

General Information:
Name(s) found:	ttn-1 / CE36723 [WormBase]
Description(s) found: SHOW ONLY BEST	WBGene00006436 locus:ttn-1 status:Partially_confirmed UniProt:A7DT28 protein_id:CCD72170.1 [WormBase] gi\|72000915\|ref\|NP_001024200.1\| TiTiN family member (ttn-1) [Caenorhabditis elegans] [NCBI NR] CE36723 WBGene00006436 locus:tag-58 status:Partially_confirmed [wormpep150.fasta] 36723 WBGene00006436 locus:tag-58 status:Partially_confirmed [wormpep130-phg-ecoli-orf-rand.fasta] CE36723 WBGene00006436 locus:ttn-1 status:Partially_confirmed UniProt:A7DT28_CAEEL protein_id:ABS83857.1 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta] CE36723 WBGene00006436 locus:ttn-1 status:Partially_confirmed UniProt:A7DT28_CAEEL protein_id:ABS83857.1\| [wormORF-contam.fasta] CE36723 WBGene00006436 locus:ttn-1 status:Partially_confirmed [wormpep160-contam.fasta] TiTiN family member (ttn-1) [Caenorhabditis elegans] [nr-271106-contam.fasta] CE36723 WBGene00006436 locus:ttn-1 status:Partially_confirmed UniProt:A7DT28 protein_id:ABS83857.1 [wormbase_c-elegans_2.11_01-10-2010_reversed.fasta] [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr] CE36723 WBGene00006436 locus:ttn-1 status:Partially_confirmed UniProt:A7DT28 protein_id:CCD72170.1 [wormbase_c_elegans_ws231_03-13-2012_reversed.fasta] Isoform of G4SLH0, Isoform c of Titin homolog OS=Caenorhabditis elegans GN=ttn-1 [CAEEL.fasta.20160308]
Organism:	Caenorhabditis elegans
Length:	3215 amino acids
Gene Ontology:
Cellular Component:	cytoplasm [IEA] extracellular region [IEA] proteinaceous extracellular matrix [IEA]
Biological Process:	DNA repair [IEA] regulation of cell growth [IEA] signal transduction [IEA] cell adhesion [IEA] blood coagulation [IEA] protein amino acid phosphorylation [IEA]
Molecular Function:	magnesium ion binding [IEA] ATP binding [IEA] protein tyrosine kinase activity [IEA] zinc ion binding [IEA] non-membrane spanning protein tyrosine kinase activity [IEA] protein kinase activity [IEA] protein serine/threonine kinase activity [IEA] insulin-like growth factor binding [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEGNEKKGGG LPPTQQRHLN IDTTVGGSIS QPVSPSMSYS TDRETVMRSA SGHATVAETH  60
   61 LIRSIGSQSQ SYTEEHWSSE ITSFVALAPP KFIQVIKAYR VHSTDTISLV VEVASDPPAI 120
  121 FEWFYNEKSV LQDRDRFQVG HGINISRLKV SRPEQGVYKC VTRNPAGVST SYGYITVNAD 180
  181 REHLSSSKED MRLQRQHSVT YHQAPRFLTQ VPNLFVTAGS NVIIDVEVDA NPPARFSWFV 240
  241 NGKEYRDSIH GVEMFSPDVN RSVVRFSIPV AGEYKVVASN VHGSAMSCGH VDIQKVIELE 300
  301 ESTLTTSTTA FDPMTTSMRA LGNNGRNSRQ AVNMFELNYT QRSSSVPRGV RHLESHIEVS 360
  361 NMTGEEKKTQ QQTRTDAASI VESRFHPQPP KPPRAGTSRR FLPEPPKFVT TLPSVITVNA 420
  421 EEKLVLSVDV QAIPAAEFAW HVNGFEVKKS QSVVLLDEHN KSTLVLHPPV KQGKYKVTAR 480
  481 NDVGSDSVTT QVTRIGEVKD GAGSEPPDIV ESAVTVTCSH EEDVGSHSSL QTVRRIQEMQ 540
  541 EEDEVDPIKP FIEATSPKVK ESVEHPFANI LNPKKREERL SPSGKGKHLL FAPRITAHPS 600
  601 ESVFKILDGS PLKLRVMASS LPPATFLWML NNFELRSNQN VTIRNDEENS SEIEFQKAPN 660
  661 GNVTVSAKNH LGEDRWTGKV ILQYESPPPG QKITTIEKVT ESWTLEEAVI TQVVPTAADP 720
  721 GDRIVIIVRF DENKTSNCQF NWTINGVNIE KLEENLVAVE STEFESSLIV EKLEEQLCGE 780
  781 VVCVVKNQHG EVFSSSAHLR IRDDDSSFEI VPPNLPEECA PKIVEPLHSA SFLDGQAMSL 840
  841 RCKITANPSA AVVWSKDDVN VEDWVLNKDV TTTVLDGGVC ELLNPECFAE DAGLYKCTAT 900
  901 NPHGTAETAA FINVEGAEYI KDHEEAEISE SVLTDDVHII LPPKFIETLT AETDNFQQLG 960
  961 YVRMVATVRS VAPITVSWQK DGMDIYENEK YEVMQFADGA QILTIRAPTN LDSGVYTCTA1020
 1021 ESEHGVSNSS CQVELTISAE SSPESFEKVE ITPPEEVKET GIDDDIEVIL KEEVSGTAQI1080
 1081 EKREEEFKLL VKVADQVAST LVANVFLEAV HEAVKKIVET EDEEEDNQIE ATQEPRFETS1140
 1141 TDEYHVKENG TIKMAATISG HPTPFLEWYF GEEKLQVSQN VSMYYEAGTS AIILKNVQKR1200
 1201 QGGNYFLRAH NCHGESILPM KLTVDPIEAV THVLETSIPK VVVEQDAKEE EVRRAAEIIS1260
 1261 EQFAQLWVQD AQTEAVSAQA HQTPVVAEQA SEEPTLPEVV AALQEQKPSV EKAPQPQFEV1320
 1321 LETEDQDVVE QMQKQLPPVQ KSMSVQEEKA SSQRTPSPMN YEDKVKTIQS NLLRVNSHEA1380
 1381 MEPIEATNLL LNTALQLKNE HVCDETTTVI VTQQPQKYDQ LVTVVESNIE YHALRLSTSS1440
 1441 SSPLKFIDLE TIIQKPSTSC ESIDRMFVEK SKRTANAQHR IVVLQGMSNT FHNAITWSLK1500
 1501 KVKKLVGDAE AKAYADVEVV KQDETNEQVM TIIDNDTIVP QLLQVAAAAN KLKLENVSVA1560
 1561 LIKEGDRAHQ ELVIEYESSI DEPMFEPVHN TSHLTFHQQQ PTGPDQHVWS RRSKFEEDEA1620
 1621 HVVAVFVEVD ANCPDQSVEI VATVNAAYEG DNRQGIEDEP FTEVSQSLAT ESSAAPQAPK1680
 1681 FLRKLVNCFG RIGEPVQLKC LIAGMPQPEI EWTVDGDPIV PNDEYSIVYE DGVCILRIES1740
 1741 TLIEDEGEYC CTASNVAGTT FSKCYLKLSE ADDDAVDLLR QLSEIKIIDP TLSTGYPMSM1800
 1801 ISDEENTSHQ LLSNVLLTDK EVPITATYNE DLSRAESFRR FFESAETTVK VTELYQGESV1860
 1861 EAQFQQPEKR EQVSTSNTDV MFVNQKVDVM ESTVSTVGNA VRQSVSSSTN SWDYMFNDPF1920
 1921 PESQEINVIE NELYEPRVPL LPQKLSYKGQ EIFANTNTVE RNSKAGAKAK GEVENLKKCV1980
 1981 ETLLLFDAEM DMKDIKESSP KKEIISKKDQ QSLDDQIKVT QQILKDVERD LNKMERTSPG2040
 2041 KSLSPNKRTF APKDVEDIEA AIFSISDQLA DRQSSEEALR EALQEMILSN SSPMKELSRN2100
 2101 NETSKPEVLK SEIQKIPEVE TKISEVYPIV KLKQAISAIE NSLLEDTEVT EIMKRKGSDK2160
 2161 DKRKATRIKR VPSAHSARIT PITSNLRDRL NQLHQLTVSE DSGSLKQNEE AKEIQELFVK2220
 2221 IEKEINTIAE LCKEKMTKKG ADTVTHVLNS VLQHVASIIN VILVAQDHQP IEVHAETTKT2280
 2281 AEVSVWYSFD VHPESEDIIG IVDEEPTNRR PSSTPRGSTR SSNLTTSQDS QATTKMTVSS2340
 2341 EDTIEAPIAP PRKGRSLSRD AERLLEIQPR APPRRSRQSG DTLSPEPTPV LTLVKSDETP2400
 2401 APVRPPRSRS RHSGDELAET SPEAQPIRPP RSHSRHSGDE LEEVQPVRPP RSKSKTADAN2460
 2461 CLQIESMDES QYSLSCIHIQ KTNFAFTNST HETSNASVVV DLRNMAQLEC TVQSLDDLAS2520
 2521 IQMLCEESDY PSDTDRSLLL AGTVRYFNRA SPSLHEVSPS LNMESVSMDL KPETEPEEIV2580
 2581 QDVYVNVELH SVPSLSSLVE VNPNTLMQTL ASEKSSLKAA EEDEKEGEEE GEEEVTADVS2640
 2641 FIGRSVLSTE TLDVVLEEKD MSQMNSTLPL DYERAFSSNT IRETDILSDE SITVDSSYHK2700
 2701 SPEPTVDFAR SQVKSEEVTE NFSLIHKPAR RRVTGIVVNS LIYTIAANIA EDNTFDVDVV2760
 2761 QEPQRYNISI KVIEDIVDFT SLTIMSDCED DPPADVLVLK QDTSKLQALS YDDISVATTR2820
 2821 TGITVSIVAR SLNDGIYASL EEIAWGEVEM TVPDIMQMST EEKSSLQFNV TVSESNLEEA2880
 2881 KSLKSQVSFR SSQNSVSEMD NTISSTATIS IPSYVVKLES TATITCELNN YLPKNCTIDW2940
 2941 YCGKTKIIID HEQFDRISHD LLEVLIIRSV EAINGNLYSL KINEDLFPVA YLIVENTNLT3000
 3001 TSANILTRPE TQFVMEGQPT VITVELDDPN VIVNWLKDRR PLHENERIRL ETDGQGNHRV3060
 3061 IIPNTCVGDQ GTYLALTSSE SVAITLVVEE RIEEKEVMVI ASGTESEEDD VQEYLVPPGS3120
 3121 TATIACELEE CELKRSIRWL RDGKDIRFEQ GKTEHVQNGL KHYLVVHDAT SLDSGLYSVC3180
 3181 ISNVEFRVAH LCVNSLTSTL HALKRKRISN NSLHN

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

The following runs contain data for this protein:

	BAIT	COMMENTS	PUBLICATION
View Run	hcp-1	hcp1 IP from december2004	Cheeseman, I.M., et al. (2005)

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.98

Protein Overview: ttn-1

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: