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Protein Overview: let-413

General Information:
Name(s) found: let-413 / CE37008 [WormBase]
Description(s) found:
Found 18 descriptions.
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  • WBGene00002632 locus:let-413 Protein lap1 status:Confirmed UniProt:O61967 protein_id:CCD70054.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 699 amino acids

    Gene Ontology:
    Cellular Component: basolateral plasma membrane [IDALink to PubMed article]
    Biological Process: embryonic development [IMPLink to PubMed article]
    actin filament-based process [IMPLink to PubMed article]
    negative regulation of multicellular organism growth [IMPLink to PubMed article]
    hermaphrodite genitalia development [IMPLink to PubMed article]
    locomotory behavior [IMPLink to PubMed article]
    cell-cell junction assembly [IMPLink to PubMed article]
    embryonic development ending in birth or egg hatching [IMPLink to PubMed articleLink to PubMed articleLink to PubMed articleLink to PubMed article]
    reproduction [IMPLink to PubMed article]
    Molecular Function: protein binding [IEALink to PubMed article][TASLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPAFFCLPMA CQRQVDSIDR SQSNLQAIPS DIFRFRKLED LNLTMNNIKE LDHRLFSLRH  60
   61 LRILDVSDNE LAVLPAEIGN LTQLIELNLN RNSIAKLPDT MQNCKLLTTL NLSSNPFTRL 120
  121 PETICECSSI TILSLNETSL TLLPSNIGSL TNLRVLEARD NLLRTIPLSI VELRKLEELD 180
  181 LGQNELEALP AEIGKLTSLR EFYVDINSLT SLPDSISGCR MLDQLDVSEN QIIRLPENLG 240
  241 RMPNLTDLNI SINEIIELPS SFGELKRLQM LKADRNSLHN LTSEIGKCQS LTELYLGQNF 300
  301 LTDLPDTIGD LRQLTTLNVD CNNLSDIPDT IGNCKSLTVL SLRQNILTEL PMTIGKCENL 360
  361 TVLDVASNKL PHLPFTVKVL YKLQALWLSE NQTQSILKLS ETRDDRKGIK VVTCYLLPQV 420
  421 DAIDGEGRSG SAQHNTDRGA FLGGPKVHFH DQADTTFEEN KEAEIHLGNF ERHNTPHPKT 480
  481 PKHKKGSIDG HMLPHEIDQP RQLSLVSNHR TSTSSFGESS NSINRDLADI RAQNGVREAT 540
  541 LSPEREERMA TSLSSLSNLA AGTQNMHTIR IQKDDTGKLG LSFAGGTSND PAPNSNGDSG 600
  601 LFVTKVTPGS AAYRCGLREG DKLIRANDVN MINASQDNAM EAIKKRETVE LVVLRRSPSP 660
  661 VSRTSEPSLN GSSHQLNHFD AGSPDSTMFV TSSTPVYAS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..373] PSI-BLAST 44.39794 No description for 2omxA was found.
    2 View Details [374..427] PSI-BLAST 27.09691 Polygalacturonase inhibiting protein PGIP
    3 View Details [428..564] deduced N/A No confident structure predictions are available.
    4 View Details [565..699] PSI-BLAST 10.154902 Erbin

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • signal transducer activity
    		•  2.54176035045352 bayes_pls_golite062009
  • molecular transducer activity
    		•  2.54176035045352 bayes_pls_golite062009
  • receptor activity
    		•  2.44108148686445 bayes_pls_golite062009
  • transmembrane receptor activity
    		•  2.25077658159974 bayes_pls_golite062009
  • protein kinase activity
    		•  1.61450095469422 bayes_pls_golite062009
  • G-protein coupled receptor activity
    		•  1.37462680876315 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
    		•  1.36168522830563 bayes_pls_golite062009
  • kinase activity
    		•  1.28067810202729 bayes_pls_golite062009
  • binding
    		•  1.23313855731605 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.875083054478353 bayes_pls_golite062009
  • protein binding
    		•  0.646159692466759 bayes_pls_golite062009
  • transferase activity
    		•  0.435331931559158 bayes_pls_golite062009
  • protein tyrosine kinase activity
    		•  0.231213253402712 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.205944109094333 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.
    4
    Term Confidence Notes
  • binding
    		•  2.6196222853442 bayes_pls_golite062009
  • protein binding
    		•  2.35875654816667 bayes_pls_golite062009
  • kinase activity
    		•  1.29833697558449 bayes_pls_golite062009
  • transporter activity
    		•  1.18978519116375 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  1.11584635608743 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  1.07211582292329 bayes_pls_golite062009
  • signal transducer activity
    		•  1.06018756723145 bayes_pls_golite062009
  • molecular transducer activity
    		•  1.06018756723145 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.851396699088923 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  0.755223974149211 bayes_pls_golite062009
  • PDZ domain binding
    		•  0.71844819286977 bayes_pls_golite062009
  • protein domain specific binding
    		•  0.64214865642772 bayes_pls_golite062009
  • protein kinase binding
    		•  0.54934142458843 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  0.549085929250683 bayes_pls_golite062009
  • kinase binding
    		•  0.541050170070789 bayes_pls_golite062009
  • receptor binding
    		•  0.359972518335054 bayes_pls_golite062009
  • transferase activity
    		•  0.325404241870749 bayes_pls_golite062009
  • beta-catenin binding
    		•  0.27594880120163 bayes_pls_golite062009
  • enzyme binding
    		•  0.265928259068924 bayes_pls_golite062009
  • actin binding
    		•  0.263747574646927 bayes_pls_golite062009
  • active transmembrane transporter activity
    		•  0.252733105474942 bayes_pls_golite062009
  • phosphatase binding
    		•  0.24515474358339 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.80

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle