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Protein Overview: pdfr-1

General Information:
Name(s) found: pdfr-1 / CE37088 [WormBase]
Description(s) found:
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  • WBGene00015735 locus:pdfr-1 Calcitonin receptor-like protein 1 status:Confirmed UniProt:Q09460 protein_id:CCD64380.1 [WormBase]
  • gi|71981664|ref|NP_001021172.1| PDF Receptor homolog family member (pdfr-1) [Caenorhabditis elegans] [NCBI NR]
  • gi|51011331|gb|AAT92086.1| Hypothetical protein C13B9.4c [Caenorhabditis elegans] [NCBI NR]
  • gi|37048694|gb|AAQ84884.1| calcitonin receptor-like protein SEB-1B [Caenorhabditis elegans] [NCBI NR]
  • gi|133907512|gb|ABO42257.1| pigment dispersing factor receptor c [Caenorhabditis elegans] [NCBI NR]
  • CE37088 WBGene00015735 status:Partially_confirmed TR:Q6W3C2 protein_id:AAT92086.1 [wormpep150.fasta]
  • 37088 WBGene00015735 status:Confirmed protein_id:AAT92086.1 [wormpep130-phg-ecoli-orf-rand.fasta]
  • calcitonin receptor-like protein SEB-1B [Caenorhabditis elegans]gi|51011331|gb|AAT92086.1| Hypothetical protein C13B9.4c [Caenorhabditis elegans] [nrdb_11152004_Chlamydomonas]
  • CE37088 WBGene00015735 status:Confirmed TR:Q6W3C2 protein_id:AAT92086.1 [wormpep132.fasta]
  • 37088 WBGene00015735 status:Partially_confirmed TR:Q6W3C2 protein_id:AAT92086.1 [wormpep150-phg-orf-ecoli-rand.fasta]
  • CE37088 WBGene00015735 locus:pdfr-1 status:Confirmed UniProt:Q6W3C2_CAEEL protein_id:AAT92086.1 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta]
  • CE37088 WBGene00015735 status:Confirmed UniProt:Q6W3C2_CAEEL protein_id:AAT92086.1| [wormORF-contam.fasta]
  • calcitonin receptor-like protein SEB-1B [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • Hypothetical protein C13B9.4c [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • C13B9.4c [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • CE37088 WBGene00015735 locus:pdfr-1 status:Confirmed UniProt:Q6W3C2 protein_id:AAT92086.1 [wormbase_c-elegans_2.11_01-10-2010_reversed.fasta]
  • [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr]
  • CE37088 WBGene00015735 locus:pdfr-1 status:Confirmed UniProt:G5EDW6 protein_id:CCD64380.1 [wormbase_c_elegans_ws231_03-13-2012_reversed.fasta]
  • CE37088 WBGene00015735 locus:pdfr-1 status:Confirmed UniProt:Q09460 protein_id:CCD64380.1 Calcitonin receptor-like protein 1 [wormpep246-ecoli-contam.fasta]
  • Isoform of Q09460, Isoform c of Calcitonin receptor-like protein 1 OS=Caenorhabditis elegans GN=pdfr-1 [CAEEL.fasta.20160308]
    • Organism: Caenorhabditis elegans
    Length: 541 amino acids

    Gene Ontology:
    Cellular Component: membrane [IEALink to PubMed article]
    Biological Process: locomotory behavior [IMPLink to PubMed article]
    positive regulation of adenylate cyclase activity [ISSLink to PubMed article]
    activation of adenylate cyclase activity by G-protein signaling pathway [ISSLink to PubMed article]
    cellular calcium ion homeostasis [ISSLink to PubMed article]
    Molecular Function: G-protein coupled receptor activity [IEALink to PubMed article]
    calcitonin receptor activity [ISSLink to PubMed articleLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MADATSPFNV SILDNSTKLS EMVESGWNVL ASTSVQAFNE AMDVLEESYP LCKKMLDHNN  60
   61 LFPERDPNDT RIWCNATYDT VLCWPPTPAN SSVTLQCPHM KGLDPNKNIT KDCHVSGVWS 120
  121 GRNAGEMGPT LPGWTNFTMC YTDEVIYIMQ NLNNESLTIA QEVARNARKL EFVGLGLSLV 180
  181 SLILAISIFS YFRRLRVFRN LLHLHLMIAM LMVVILRLVL YIDLIFTGEN GPHTNSAEGK 240
  241 TINTMPIVCE GMFFFLEYFK TVTFCWMFLE GIYLNNQIVF GFFNSEPKLL PYFIAGYGIP 300
  301 LVHTMLWLLV VLIKKDFKVE RCLGSYYLEP EFWILDGPRM AELVINLFFI CNVIRVLYSK 360
  361 VRESNNTSEA GLKKSVKAAM MLLPLLGVPN IMQTIPFAPT RDNIMVFAVW TYTASFTYMY 420
  421 QGLMVASIYC FTNKEVNHVL KTFYARYRLL HKSQNELRRG SRSVASHYAA KNGTANASAP 480
  481 QTNNADEFGK LSPFPSRSKK GSDDSTTKLM KDAVMEEEKN ANNNGYGSAG EMTPLREGYE 540
  541 E

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..90] PSI-BLAST 19.30103 Frizzled 8 (FZ8)
    2 View Details [91..139] FFAS03 1.84 3D NMR structure of the first extracellular domain of CRFR-2beta, a type B1 G-protein coupled receptor
    3 View Details [140..541] PSI-BLAST 51.522879 Rhodopsin

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • transmembrane receptor activity
    		•  4.38708793497137 bayes_pls_golite062009
  • receptor activity
    		•  4.1046853496316 bayes_pls_golite062009
  • signal transducer activity
    		•  3.17034085692897 bayes_pls_golite062009
  • molecular transducer activity
    		•  3.17034085692897 bayes_pls_golite062009
  • Wnt receptor activity
    		•  2.95244120669902 bayes_pls_golite062009
  • binding
    		•  2.18217693324765 bayes_pls_golite062009
  • protein binding
    		•  2.15165760199286 bayes_pls_golite062009
  • Wnt-protein binding
    		•  2.04664201899031 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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