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Protein Overview: pdfr-1

General Information:
Name(s) found: pdfr-1 / CE37087 [WormBase]
Description(s) found:
Found 20 descriptions.
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  • WBGene00015735 locus:pdfr-1 Calcitonin receptor-like protein 1 status:Confirmed UniProt:Q09460 protein_id:CCD64379.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 536 amino acids

    Gene Ontology:
    Cellular Component: membrane [IEALink to PubMed article]
    Biological Process: locomotory behavior [IMPLink to PubMed article]
    positive regulation of adenylate cyclase activity [ISSLink to PubMed article]
    activation of adenylate cyclase activity by G-protein signaling pathway [ISSLink to PubMed article]
    cellular calcium ion homeostasis [ISSLink to PubMed article]
    Molecular Function: G-protein coupled receptor activity [IEALink to PubMed article]
    calcitonin receptor activity [ISSLink to PubMed articleLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MADATSPFNV SILDNSTKLS EMVESGWNVL ASTSVQAFNE AMDVLEESYP LCKKMLDHNN  60
   61 LFPERDPNDT RIWCNATYDT VLCWPPTPAN SSVTLQCPHM KGLDPNKYIV KRCDETGRWA 120
  121 GKKPGHYENP WGWTNFTVCF KIDYEDAKIA QEVARNARKL EFVGLGLSLV SLILAISIFS 180
  181 YFRRLRVFRN LLHLHLMIAM LMVVILRLVL YIDLIFTGEN GPHTNSAEGK TINTMPIVCE 240
  241 GMFFFLEYFK TVTFCWMFLE GIYLNNQIVF GFFNSEPKLL PYFIAGYGIP LVHTMLWLLV 300
  301 VLIKKDFKVE RCLGSYYLEP EFWILDGPRM AELVINLFFI CNVIRVLYSK VRESNNTSEA 360
  361 GLKKSVKAAM MLLPLLGVPN IMQTIPFAPT RDNIMVFAVW TYTASFTYMY QGLMVASIYC 420
  421 FTNKEVNHVL KTFYARYRLL HKSQNELRRG SRSVASHYAA KNGTANASAP QTNNADEFGK 480
  481 LSPFPSRSKK GSDDSTTKLM KDAVMEEEKN ANNNGYGSAG EMTPLREGSN RSTKSP

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..134] PSI-BLAST 16.30103 No description for 2jodA was found.
    2 View Details [135..536] PSI-BLAST 47.0 Rhodopsin

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • G-protein coupled receptor activity
    		•  7.11838006478957 bayes_pls_golite062009
  • transmembrane receptor activity
    		•  5.41031049482732 bayes_pls_golite062009
  • receptor activity
    		•  5.12318570081263 bayes_pls_golite062009
  • signal transducer activity
    		•  4.16951678107564 bayes_pls_golite062009
  • molecular transducer activity
    		•  4.16951678107564 bayes_pls_golite062009
  • pituitary adenylate cyclase-activating polypeptide receptor activity
    		•  2.36627671354861 bayes_pls_golite062009
  • binding
    		•  1.90935265027969 bayes_pls_golite062009
  • peptide binding
    		•  1.37672683415634 bayes_pls_golite062009
  • secretin receptor activity
    		•  1.31302501580264 bayes_pls_golite062009
  • growth hormone-releasing hormone receptor activity
    		•  0.621179725102141 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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