Protein Overview: OAF1

General Information:
Name(s) found:	OAF1 / YAL051W [SGD]
Description(s) found: SHOW ONLY BEST	gi\|97536898\|sp\|P39720.2\|OAF1_YEAST RecName: Full=Oleate-activated transcription factor 1 [NCBI NR] gi\|83853957\|gb\|AAC04981.2\| Yaf1p: CYP1-like transcription factor with zinc finger motif [Saccharomyces cerevisiae] [NCBI NR] gi\|50593114\|ref\|NP_009349.2\| Oleate-activated transcription factor, acts alone and as a heterodimer with Pip2p; activates genes involved in beta-oxidation of fatty acids and peroxisome organization and biogenesis; Oaf1p [Saccharomyces cerevisiae] [NCBI NR] Oleate-activated transcription factor 1 OS=Saccharomyces cerevisiae GN=OAF1 PE=1 SV=2 [Swiss-Prot] OAF1 Peroxisome proliferating transcription factor [mips] Oleate-activated transcription factor, acts alone and as a heterodimer with Pip2p; activates genes involved in beta-oxidation of fatty acids and peroxisome organization and biogenesis [SGD] OAF1 SGDID:S0000048, Chr I from 48565-51708, Verified ORF [10112005cervSGD.fasta] Oaf1p [Saccharomyces cerevisiae] [nrdb_11152004_Chlamydomonas] OAF1 SGDID:S000000048, Chr I from 48565-51708, Verified ORF, "Oleate-activated transcription factor, acts alone and as a heterodimer with Pip2p; activates genes involved in beta-oxidation of fatty acids and peroxisome organization and biogenesis" [SGD_S-cerevisiae_na_12-16-2005_con_reversed.fasta] Oleate-activated transcription factor 1 [nr-271106-contam.fasta] Oleate-activated transcription factor, acts alone and as a heterodimer with Pip2p; activates genes involved in beta-oxidation of fatty acids and peroxisome organization and biogenesis; Oaf1p [Saccharomyces cerevisiae] [nr-271106-contam.fasta] Yaf1p: CYP1-like transcription factor with zinc finger motif [Saccharomyces cerevisiae] [nr-271106-contam.fasta] [chemostatdb.fasta]
Organism:	Saccharomyces cerevisiae
Length:	1047 amino acids
Gene Ontology:
Cellular Component:	nucleus [IPI]
Biological Process:	peroxisome organization [IGI][IMP] positive regulation of transcription [IGI][IMP][IPI] fatty acid metabolic process [IGI][IMP]
Molecular Function:	DNA binding [IDA][IPI][ISS] transcription activator activity [IMP][IPI][ISS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVENSTQKAP HAGNDDNSST KPYSEAFFLG FNNPTPGLEA EHSSTSPAPE NSETHNRKRN  60
   61 RILFVCQACW KSKTKCDREK PECGRCVKHG LKCVYDVSKQ PAPRIPSKDA IISRLEKDMF 120
  121 YWKDKAMKLL TEREVNESGK RSASPINTNN ASGDSPDTKK QHKMEPIYEQ SGNGDINNGT 180
  181 RNDIEINLYR SHPTMIMSKV MKREVKPLSE NYIIIQDCFL KILVTSVFLD TSKNTMIPAL 240
  241 TANANITRAQ PSVANNLLKL KEMLIRQCQT EDEKNRVNEF TDRILQNTNS NRNLKIGMLL 300
  301 SMLYNSVGYQ YLEDHCPQGG EYSDLLRNLI NECEAILPSY EIIERYKNHF YEYVYPSLPF 360
  361 IELEIFEESL SQTIFPDPNN PSKVQIRMGS THLRAKVENL SLLLVILKLS YMSIRFLDHS 420
  421 TADSSFYLSK EIIDKYPIPN DFILLSPRCL ASENWCACAN ENIISCLLYI WSFFAFSPEE 480
  481 GDFFLEHPTD VISSLIMMLS TSIGLHRDPS DFPQLISPST SDKRTLNHRR ILWLSIVTVC 540
  541 SFEASLKGRH SVSPISLMAL FLNIKDPDSL TVYMNRVRGD LSDINNHTLL RIHKFTFKRA 600
  601 QLALLLSDLD NLTMTYYGSF HLHSIEFIRE KIEIFVEENF PIVPLKSVAQ DKSDLDDMNV 660
  661 ISEMNILSSE NSSSFHNRIM NKLLMLRTSM AVFLHFETLI TKDKSIFPFY KKYFMVSCMD 720
  721 ALSLINYFNK FFNGEYRHAI SSLTSFNVTK FIQLALSSTI FSLLGIILRI GLAIHMLSSE 780
  781 VQKLSGTTDP RIKELNTKVE KFSTLQRDLE SALEGIYCSA SEHLRFTYFP VFKMLALFDV 840
  841 IVQRMRKGEL WHGIFTMIQM EQMHSRIIKT LSITLGVKLD KKDRLLEELM ACNHVANFSV 900
  901 EDIDELNRNI KKEIQISSGL KPPVNTIDLT NGEPFGNAVP TFTKTWSSSL DNLEKLSSAA 960
  961 AVGQSLDYNS GLRQGPLAGG GSKEQTPIAG MNNLNNSINA TPIVDNSSGS QLPNGFDRGQ1020
 1021 ANNTPFPGYF GGLDLFDYDF LFGNDFA

Protein Complex Data

	PUBLICATION	TOPOLOGY	COCOMPLEXED PROTEINS
View Details	(MIPS) Mewes HW, et al. (2004)		OAF1 PIP2
View Details	Krogan NJ, et al. (2006)		FIG4 KRE5 OAF1 VAC14

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

	BAIT	PREY	HITS	PUBLICATION
View Screen	MET30	OAF1	1	Unpublished Fields Lab Data
View Screen	CAB3	OAF1	1	Hazbun TR, et al. (2003)
View Screen	CAB3	OAF1	1	Unpublished Fields Lab Data
View Screen	YLR224W	OAF1	1	Unpublished Fields Lab Data
View Screen	PSE1	OAF1	1	Unpublished Fields Lab Data
View Screen	SPO21	OAF1	1	Unpublished Fields Lab Data

Microscopy / Localization Data

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No microscopy data found in the PDR for this protein.

Protein Structure Data

Philius Transmembrane Prediction:

[View Details]

Source: Reynolds et al. 2008. Manuscript submitted