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Protein Overview: FLO8

General Information:
Name(s) found: FLO8 / YER109C [SGD]
Description(s) found:
Found 11 descriptions.
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  • Transcription factor required for flocculation, diploid filamentous growth, and haploid invasive growth; genome reference strain S288C and most laboratory strains have a mutation in this gene [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 799 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article][TASLink to PubMed article]
    cytoplasm [IDALink to PubMed article]
    Biological Process: pseudohyphal growth [TASLink to PubMed article]
    flocculation via cell wall protein-carbohydrate interaction [IMPLink to PubMed article]
    invasive growth in response to glucose limitation [TASLink to PubMed article]
    biofilm formation [IMPLink to PubMed article]
    Molecular Function: specific RNA polymerase II transcription factor activity [TASLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSYKVNSSYP DSIPPTEQPY MASQYKQDLQ SNIAMATNSE QQRQQQQQQQ QQQQQWINQP  60
   61 TAENSDLKEK MNCKNTLNEY IFDFLTKSSL KNTAAAFAQD AHLDRDKGQN PVDGPKSKEN 120
  121 NGNQNTFSKV VDTPQGFLYE W*QIFWDIFN TSSSRGGSEF AQQYYQLVLQ EQRQEQIYRS 180
  181 LAVHAARLQH DAERRGEYSN EDIDPMHLAA MMLGNPMAPA VQMRNVNMNP IPIPMVGNPI 240
  241 VNNFSIPPYN NANPTTGATA VAPTAPPSGD FTNVGPTQNR SQNVTGWPVY NYPMQPTTEN 300
  301 PVGNPCNNNT TNNTTNNKSP VNQPKSLKTM HSTDKPNNVP TSKSTRSRSA TSKAKGKVKA 360
  361 GLVAKRRRKN NTATVSAGST NACSPNITTP GSTTSEPAMV GSRVNKTPRS DIATNFRNQA 420
  421 IIFGEEDIYS NSKSSPSLDG ASPSALASKQ PTKVRKNTKK ASTSAFPVES TNKLGGNSVV 480
  481 TGKKRSPPNT RVSRRKSTPS VILNADATKD ENNMLRTFSN TIAPNIHSAP PTKTANSLPF 540
  541 PGINLGSFNK PAVSSPLSSV TESCFDPESG KIAGKNGPKR AVNSKVSASS PLSIATPRSG 600
  601 DAQKQRSSKV PGNVVIKPPH GFSTTNLNIT LKNSKIITSQ NNTVSQELPN GGNILEAQVG 660
  661 NDSRSSKGNR NTLSTPEEKK PSSNNQGYDF DALKNSSSLL FPNQAYASNN RTPNENSNVA 720
  721 DETSASTNSG DNDNTLIQPS SNVGTTLGPQ QTSTNENQNV HSQNLKFGNI GMVEDQGPDY 780
  781 DLNLLDTNEN DFNFINWEG

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run MLP2 #03 Alpha Factor Prep1-TiO2 Flowthrough Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..189] MSA 9.018997 View MSA. No confident structure predictions are available.
    2 View Details [190..323] deduced N/A No confident structure predictions are available.
    3 View Details [324..545] deduced N/A No confident structure predictions are available.
    4 View Details [546..798] deduced N/A No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle