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Protein Overview: MCA5_ARATH

General Information:
Name(s) found: MCA5_ARATH [Swiss-Prot]
Description(s) found:
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  • gi|75219813|sp|O64518.1|MCA5_ARATH RecName: Full=Metacaspase-5; Short=AtMC5; AltName: Full=Metacaspase-6 [NCBI NR]
  • pir||T01022 hypothetical protein YUP8H12R.5 - Arabidopsis thaliana [NCBI NR]
  • gi|37788553|gb|AAP44518.1| metacaspase 5 precursor [Arabidopsis thaliana] [NCBI NR]
  • gi|32482828|gb|AAP84714.1| metacaspase 6 [Arabidopsis thaliana] [NCBI NR]
  • gi|3152557|gb|AAC17038.1| Contains similarity to S. cerevisiae hypothetical protein YOR197w, gb|Z75105. EST gb|T76227 comes from this gene [Arabidopsis thaliana] [NCBI NR]
  • gi|15219342|ref|NP_178051.1| ATMC5 (ARABIDOPSIS THALIANA METACASPASE 5); cysteine-type endopeptidase [Arabidopsis thaliana] [NCBI NR]
  • gi|116325934|gb|ABJ98568.1| At1g79330 [Arabidopsis thaliana] [NCBI NR]
  • Metacaspase-5 OS=Arabidopsis thaliana GN=AMC5 PE=1 SV=1 [Swiss-Prot]
  • (O64518) YUP8H12R.5 protein (Metacaspase 6) [athaliana3702.FASTAC.txt]
  • metacaspase 5 [Arabidopsis thaliana]gi|32482828|gb|AAP84714.1| metacaspase 6 [Arabidopsis thaliana]gi|3152557|gb|AAC17038.1| Contains similarity to S. cerevisiae hypothetical protein YOR197w, gb|Z75105. EST gb|T76227 comes from this gene. [Arabidopsis [nrdb_11152004_Chlamydomonas]
  • Tax_Id=3702 Metacaspase AtMCPb2/AMC6 [EBI-IPI_Arabidopsis_3.11_12-06-2005_reversed.fasta]
  • | Symbols: AMC6, ATMCP2B, ATMC5 | AMC6/ATMC5/ATMCP2B (TYPE-II METACASPASES); caspase/ cysteine-type endopeptidase | chr1:29843615-29845030 FORWARD [TAIR_Arabidopsis_na_04-12-2008_con_reversed.fasta]
  • metacaspase 5 precursor [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • metacaspase 6 [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • AMC6/ATMCP2B; caspase/ cysteine-type endopeptidase [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • Contains similarity to S. cerevisiae hypothetical protein YOR197w, gb|Z75105. EST gb|T76227 comes from this gene. [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • At1g79330 [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • | Symbols: AMC6, ATMCP2B, ATMC5, MC5 | metacaspase 5 | chr1:29838722-29840137 FORWARD LENGTH=410 [TAIR_A_Thaliana_10_12-14-2010_reversed.fasta]
    • Organism: Arabidopsis thaliana
    Length: 410 amino acids

    Gene Ontology:
    Cellular Component: chloroplast [IDA]
    Biological Process: induction of apoptosis [IDA]
    Molecular Function: cysteine-type endopeptidase activity [IDA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAKKAVLIGI NYPGTKAELR GCVNDVRRVH KSLVDRFGFS ERNITELIDT DESSTKPTGK  60
   61 NIRRALLNLV ESAKPGDVLV VHYSGHGTRL PAETGEDDDT GYDECIVPCD MNLITDDEFR 120
  121 DLVEKVPKEA HITIISDSCH SGGLIDEAKE QIGESTKKKP KKESGGSSGL GIKGFVREAV 180
  181 EEALESKGIA IPHHKDEKDE NKTKELKLED GAKVHVVNKS LPLQTLIDIL KQNTGNNDIE 240
  241 VGKIRPTLFN VFGEDASPKV KKFMKVILTK LQEGKTEGGI LGMIGKLAQE FLKHKLNDDE 300
  301 EYVKPAMKTH VGNKQEVYAG ASNGSLADNG ILISGCQTDQ TSADASPQGH PEMAYGAFTN 360
  361 AVQIILEETK GMITYKELVL KARKLLKKQG FSQRPGLYCS DSFVNAPFIC

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..236] PSI-BLAST 7.221849 No description for 2j31A was found.
    2 View Details [237..410] FFAS03 1.28 Caspase-9

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • catalytic activity
    		•  0.446816200197746 bayes_pls_golite062009
  • binding
    		•  0.128865592323915 bayes_pls_golite062009
  • hydrolase activity
    		•  0.00345801703057891 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.85

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle