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Protein Overview: MAOP1_ARATH

General Information:
Name(s) found: MAOP1_ARATH [Swiss-Prot]
Description(s) found:
Found 13 descriptions.
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  • NADP-dependent malic enzyme 1 OS=Arabidopsis thaliana GN=NADP-ME1 PE=1 SV=1 [Swiss-Prot]
    • Organism: Arabidopsis thaliana
    Length: 581 amino acids

    Gene Ontology:
    Cellular Component: cellular_component [ND]
    Biological Process: malate metabolic process [IEA][ISS]
    metabolic process [IEA]
    oxidation reduction [IEA]
    Molecular Function: malic enzyme activity [ISS]
    malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+) activity [IDA]
    oxidoreductase activity, acting on NADH or NADPH, NAD or NADP as acceptor [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEKVTNSDLK SSVDGGVVDV YGEDSATIEH NITPWSLSVS SGYSLLRDPR YNKGLAFTEK  60
   61 ERDTHYLRGL LPPVVLDQKL QEKRLLNNIR QYQFPLQKYM ALTELQERNE RLFYKLLIDN 120
  121 VEELLPIVYT PTVGEACQKF GSIFRRPQGL FISLKDKGKI LDVLKNWPER NIQVIVVTDG 180
  181 ERILGLGDLG CQGMGIPVGK LALYSALGGV RPSACLPVTI DVGTNNEKLL NDEFYIGLRQ 240
  241 KRATGQEYSE LLNEFMSAVK QNYGEKVLIQ FEDFANHNAF ELLAKYSDTH LVFNDDIQGT 300
  301 ASVVLAGLVS AQKLTNSPLA EHTFLFLGAG EAGTGIAELI ALYMSKQMNA SVEESRKKIW 360
  361 LVDSKGLIVN SRKDSLQDFK KPWAHEHEPV KDLLGAIKAI KPTVLIGSSG VGRSFTKEVI 420
  421 EAMSSINERP LIMALSNPTT QSECTAEEAY TWSKGRAIFA SGSPFDPVEY EGKVFVSTQA 480
  481 NNAYIFPGFG LGLVISGAIR VHDDMLLAAA EALAGQVSKE NYEKGMIYPS FSSIRKISAQ 540
  541 IAANVATKAY ELGLAGRLPR PKDIVKCAES SMYSPTYRLY R

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..581] PSI-BLAST 1000.0 Mitochondrial NAD(P)-dependenent malic enzyme

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • malate dehydrogenase activity
    		•  4.38786524125089 bayes_pls_golite062009
  • oxidoreductase activity
    		•  3.09625241707629 bayes_pls_golite062009
  • catalytic activity
    		•  1.79741889688267 bayes_pls_golite062009
  • oxidoreductase activity, acting on CH-OH group of donors
    		•  1.65338499044318 bayes_pls_golite062009
  • oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
    		•  1.47309297191111 bayes_pls_golite062009
  • oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor
    		•  1.29842732066898 bayes_pls_golite062009
  • alcohol dehydrogenase (NAD) activity
    		•  1.27032644348698 bayes_pls_golite062009
  • malic enzyme activity
    		•  1.2147813077436 bayes_pls_golite062009
  • retinol dehydrogenase activity
    		•  1.16811519855038 bayes_pls_golite062009
  • oxidoreductase activity, acting on NADH or NADPH
    		•  1.01627645289834 bayes_pls_golite062009
  • NAD or NADH binding
    		•  0.74536049628503 bayes_pls_golite062009
  • alcohol dehydrogenase activity, zinc-dependent
    		•  0.729242797855749 bayes_pls_golite062009
  • monovalent inorganic cation transmembrane transporter activity
    		•  0.527946013169731 bayes_pls_golite062009
  • DNA binding
    		•  0.525227236870065 bayes_pls_golite062009
  • glutamate dehydrogenase (NADP+) activity
    		•  0.476857036112561 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.459537641913493 bayes_pls_golite062009
  • binding
    		•  0.429102711245135 bayes_pls_golite062009
  • coenzyme binding
    		•  0.35922330382799 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.152651308844322 bayes_pls_golite062009
  • malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+) activity
    		•  0.120195861875768 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.80

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle