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Protein Overview: ODP25_ARATH

General Information:
Name(s) found: ODP25_ARATH [Swiss-Prot]
Description(s) found:
Found 13 descriptions.
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  • Dihydrolipoyllysine-residue acetyltransferase component 5 of pyruvate dehydrogenase complex, chloroplastic OS=Arabidopsis thaliana GN=EMB3003 PE=2 SV=1 [Swiss-Prot]
    • Organism: Arabidopsis thaliana
    Length: 465 amino acids

    Gene Ontology:
    Cellular Component: chloroplast [IDA]
    cytosolic ribosome [IDA]
    chloroplast envelope [IDA]
    plasma membrane [IDA]
    Biological Process: embryonic development ending in seed dormancy [NAS]
    Molecular Function: protein binding [IEA]
    acyltransferase activity [IEA]
    dihydrolipoyllysine-residue acetyltransferase activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSRLLQTPFL PSVSLPTKTR SSVTGFRVKP RIIPIQAKIR EIFMPALSST MTEGKIVSWV  60
   61 KSEGDKLNKG ESVVVVESDK ADMDVETFYD GYLAAIMVEE GGVAPVGSAI ALLAETEDEI 120
  121 ADAKAKASGG GGGGDSKAPP ASPPTAAVEA PVSVEKKVAA APVSIKAVAA SAVHPASEGG 180
  181 KRIVASPYAK KLAKELKVEL AGLVGSGPMG RIVAKDVEAV AAGGGVQAAV AVKEVVAAPG 240
  241 VELGSVVPFT TMQGAVSRNM VESLGVPTFR VGYTISTDAL DALYKKIKSK GVTMTALLAK 300
  301 ATALALAKHP VVNSSCRDGN SFVYNSSINV AVAVAIDGGL ITPVLQNADK VDIYSLSRKW 360
  361 KELVDKARAK QLQPQEYNTG TFTLSNLGMF GVDRFDAILP PGTGAIMAVG ASQPSVVATK 420
  421 DGRIGMKNQM QVNVTADHRV IYGADLAQFL QTLASIIEDP KDLTF

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..239] PSI-BLAST 23.221849 The crystal structure of dihydrolipoamide dehydrogenase and dihydrolipoamide dehydrogenase-binding protein (didomain) subcomplex of human pyruvate dehydrogenase complex.
    2 View Details [240..465] PSI-BLAST 83.39794 Dihydrolipoamide succinyltransferase

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • dihydrolipoyllysine-residue acetyltransferase activity
    		•  9.65061123545754 bayes_pls_golite062009
  • dihydrolipoamide S-acyltransferase activity
    		•  9.64995677986911 bayes_pls_golite062009
  • S-acetyltransferase activity
    		•  9.49696044977584 bayes_pls_golite062009
  • S-acyltransferase activity
    		•  8.45313874919036 bayes_pls_golite062009
  • pyruvate dehydrogenase activity
    		•  8.17557182322815 bayes_pls_golite062009
  • pyruvate dehydrogenase (acetyl-transferring) activity
    		•  6.40483178382327 bayes_pls_golite062009
  • acetyltransferase activity
    		•  6.08159176722072 bayes_pls_golite062009
  • oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
    		•  5.93985773477717 bayes_pls_golite062009
  • transferase activity, transferring acyl groups other than amino-acyl groups
    		•  5.74314131636952 bayes_pls_golite062009
  • acyltransferase activity
    		•  5.72047003788767 bayes_pls_golite062009
  • transferase activity, transferring acyl groups
    		•  5.47973101916847 bayes_pls_golite062009
  • S-succinyltransferase activity
    		•  4.10308166636667 bayes_pls_golite062009
  • dihydrolipoyllysine-residue succinyltransferase activity
    		•  4.10308166636667 bayes_pls_golite062009
  • carnitine O-acyltransferase activity
    		•  2.07401053954424 bayes_pls_golite062009
  • oxidoreductase activity, acting on the aldehyde or oxo group of donors
    		•  1.78431187655869 bayes_pls_golite062009
  • catalytic activity
    		•  1.51562638409295 bayes_pls_golite062009
  • succinyltransferase activity
    		•  1.14502959978145 bayes_pls_golite062009
  • transferase activity
    		•  1.08341671157927 bayes_pls_golite062009
  • O-acyltransferase activity
    		•  0.731328511162172 bayes_pls_golite062009
  • carnitine O-acetyltransferase activity
    		•  0.203430690130141 bayes_pls_golite062009
  • O-palmitoyltransferase activity
    		•  0.0797707245124104 bayes_pls_golite062009
  • carnitine O-palmitoyltransferase activity
    		•  0.0797707245124104 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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