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Protein Overview: MAO1_ARATH

General Information:
Name(s) found: MAO1_ARATH [Swiss-Prot]
Description(s) found:
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  • gi|4558661|gb|AAD22679.1| malate oxidoreductase (malic enzyme) [Arabidopsis thaliana] [NCBI NR]
  • pir||E84508 malate oxidoreductase (malic enzyme) [imported] - Arabidopsis thaliana [NCBI NR]
  • gi|24030498|gb|AAN41396.1| putative malate oxidoreductase (malic enzyme) [Arabidopsis thaliana] [NCBI NR]
  • gi|20268709|gb|AAM14058.1| putative malate oxidoreductase (malic enzyme) [Arabidopsis thaliana] [NCBI NR]
  • gi|15225438|ref|NP_178980.1| malate oxidoreductase, putative [Arabidopsis thaliana] [NCBI NR]
  • NAD-dependent malic enzyme 1, mitochondrial OS=Arabidopsis thaliana GN=NAD-ME1 PE=1 SV=1 [Swiss-Prot]
  • (Q9SIU0) Malate oxidoreductase (Malic enzyme) [athaliana3702.FASTAC.txt]
  • putative malate oxidoreductase (malic enzyme) [Arabidopsis thaliana]gi|20268709|gb|AAM14058.1| putative malate oxidoreductase (malic enzyme) [Arabidopsis thaliana]gi|4558661|gb|AAD22679.1| malate oxidoreductase (malic enzyme) [Arabidopsis thaliana]gi|1 [nrdb_11152004_Chlamydomonas]
  • Tax_Id=3702 Malate oxidoreductase [EBI-IPI_Arabidopsis_3.11_12-06-2005_reversed.fasta]
  • | Symbols: | malate oxidoreductase, putative | chr2:5657171-5662185 FORWARD [TAIR_Arabidopsis_na_04-12-2008_con_reversed.fasta]
  • malate oxidoreductase (malic enzyme) [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • putative malate oxidoreductase (malic enzyme) [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • malic enzyme/ oxidoreductase, acting on NADH or NADPH, NAD or NADP as acceptor [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • | Symbols: NAD-ME1 | NAD-dependent malic enzyme 1 | chr2:5650089-5655103 FORWARD LENGTH=623 [TAIR_A_Thaliana_10_12-14-2010_reversed.fasta]
    • Organism: Arabidopsis thaliana
    Length: 623 amino acids

    Gene Ontology:
    Cellular Component: chloroplast [IDA]
    mitochondrion [IDA][ISS]
    Biological Process: malate metabolic process [ISS]
    response to salt stress [IEP]
    Molecular Function: ATP binding [IDA]
    zinc ion binding [IDA]
    malic enzyme activity [ISS]
    oxidoreductase activity, acting on NADH or NADPH, NAD or NADP as acceptor [ISS]
    cobalt ion binding [IDA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGIANKLRLS SSSLSRILHR RILYSSAVRS FTTSEGHRPT IVHKQGLDIL HDPWFNKGTA  60
   61 FTMTERNRLD LRGLLPPNVM DSEQQIFRFM TDLKRLEEQA RDGPSDPNAL AKWRILNRLH 120
  121 DRNETMYYKV LINNIEEYAP IVYTPTVGLV CQNYSGLFRR PRGMYFSAED RGEMMSMVYN 180
  181 WPAEQVDMIV VTDGSRILGL GDLGVHGIGI AVGKLDLYVA AAGINPQRVL PVMIDVGTNN 240
  241 EKLRNDPMYL GLQQRRLEDD DYIDVIDEFM EAVYTRWPHV IVQFEDFQSK WAFKLLQRYR 300
  301 CTYRMFNDDV QGTAGVAIAG LLGAVRAQGR PMIDFPKMKI VVAGAGSAGI GVLNAARKTM 360
  361 ARMLGNTETA FDSAQSQFWV VDAQGLITEG RENIDPEAQP FARKTKEMER QGLKEGATLV 420
  421 EVVREVKPDV LLGLSAVGGL FSKEVLEAMK GSTSTRPAIF AMSNPTKNAE CTPQDAFSIL 480
  481 GENMIFASGS PFKNVEFGNG HVGHCNQGNN MYLFPGIGLG TLLSGAPIVS DGMLQAASEC 540
  541 LAAYMSEEEV LEGIIYPPIS RIRDITKRIA AAVIKEAIEE DLVEGYREMD AREIQKLDEE 600
  601 GLMEYVENNM WNPEYPTLVY KDD

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..623] PSI-BLAST 1000.0 Mitochondrial NAD(P)-dependenent malic enzyme

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • malate dehydrogenase activity
    		•  8.2923573833126 bayes_pls_golite062009
  • malic enzyme activity
    		•  6.14953296739671 bayes_pls_golite062009
  • malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+) activity
    		•  3.85693345778103 bayes_pls_golite062009
  • oxidoreductase activity
    		•  3.54983447672782 bayes_pls_golite062009
  • oxidoreductase activity, acting on CH-OH group of donors
    		•  2.66605122152932 bayes_pls_golite062009
  • catalytic activity
    		•  2.0643953589843 bayes_pls_golite062009
  • shikimate 5-dehydrogenase activity
    		•  1.82286236344978 bayes_pls_golite062009
  • oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
    		•  1.54527841865655 bayes_pls_golite062009
  • oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor
    		•  1.29842732066898 bayes_pls_golite062009
  • alcohol dehydrogenase (NAD) activity
    		•  1.27032644348698 bayes_pls_golite062009
  • binding
    		•  1.21980641378611 bayes_pls_golite062009
  • retinol dehydrogenase activity
    		•  1.16811519855038 bayes_pls_golite062009
  • oxidoreductase activity, acting on NADH or NADPH
    		•  1.01627645289834 bayes_pls_golite062009
  • NAD or NADH binding
    		•  0.74536049628503 bayes_pls_golite062009
  • alcohol dehydrogenase activity, zinc-dependent
    		•  0.729242797855749 bayes_pls_golite062009
  • oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor
    		•  0.66392365734856 bayes_pls_golite062009
  • monovalent inorganic cation transmembrane transporter activity
    		•  0.527946013169731 bayes_pls_golite062009
  • DNA binding
    		•  0.525227236870065 bayes_pls_golite062009
  • glutamate dehydrogenase (NADP+) activity
    		•  0.476857036112561 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.459537641913493 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.152651308844322 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.67

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle