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Protein Overview: NTH1_ARATH

General Information:
Name(s) found: NTH1_ARATH [Swiss-Prot]
Description(s) found:
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  • gi|20198157|gb|AAD26474.2| putative endonuclease [Arabidopsis thaliana] [NCBI NR]
  • gi|18402669|ref|NP_565725.1| endonuclease-related [Arabidopsis thaliana] [NCBI NR]
  • Endonuclease III homolog 1, chloroplastic OS=Arabidopsis thaliana GN=NTH1 PE=2 SV=2 [Swiss-Prot]
  • (Q9SIC4) Putative endonuclease [athaliana3702.FASTAC.txt]
  • putative endonuclease [Arabidopsis thaliana]gi|18402669|ref|NP_565725.1| endonuclease-related [Arabidopsis thaliana] [nrdb_11152004_Chlamydomonas]
  • Tax_Id=3702 Endonuclease-related [EBI-IPI_Arabidopsis_3.11_12-06-2005_reversed.fasta]
  • | Symbols: | endonuclease-related | chr2:13408395-13411211 REVERSE [TAIR_Arabidopsis_na_04-12-2008_con_reversed.fasta]
  • DNA binding / endonuclease/ iron ion binding [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • putative endonuclease [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • | Symbols: ATNTH1 | DNA glycosylase superfamily protein | chr2:13401318-13404134 REVERSE LENGTH=379 [TAIR_A_Thaliana_10_12-14-2010_reversed.fasta]
  • Endonuclease III OS=Arabidopsis thaliana GN=ATNTH1 PE=4 SV=2 [ARATH-contam.fasta]
    • Organism: Arabidopsis thaliana
    Length: 379 amino acids

    Gene Ontology:
    Cellular Component: chloroplast nucleoid [IDA]
    Biological Process: base-excision repair [IDA][ISS]
    Molecular Function: DNA N-glycosylase activity [IDA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MILLVNGGAA TSIHPNAARF YRIGTMSRQI HGAVSSSKHI SLKTQHPLSD SNSELAYGAS  60
   61 GSETRVYTRK KRLKQEPFEP LEKYSGKGVN THKLCGLPDI EDFAYKKTIG SPSSSRSTET 120
  121 SITVTSVKTA GYPPENWVEV LEGIRQMRSS EDAPVDSMGC DKAGSFLPPT ERRFAVLLGA 180
  181 LLSSQTKDQV NNAAIHRLHQ NGLLTPEAVD KADESTIKEL IYPVGFYTRK ATYMKKIARI 240
  241 CLVKYDGDIP SSLDDLLSLP GIGPKMAHLI LHIAWNDVQG ICVDTHVHRI CNRLGWVSRP 300
  301 GTKQKTTSPE ETRVALQQWL PKEEWVAINP LLVGFGQMIC TPIRPRCEAC SVSKLCPAAF 360
  361 KETSSPSSKL KKSNRSKEP

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..135] MSA 1.296996 View MSA. No confident structure predictions are available.
    2 View Details [136..379] PSI-BLAST 56.0 Endonuclease III

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • DNA N-glycosylase activity
    		•  4.08559331236111 bayes_pls_golite062009
  • hydrolase activity, hydrolyzing N-glycosyl compounds
    		•  3.73234184319832 bayes_pls_golite062009
  • DNA-(apurinic or apyrimidinic site) lyase activity
    		•  3.12421941323765 bayes_pls_golite062009
  • hydrolase activity, acting on glycosyl bonds
    		•  2.54759386266723 bayes_pls_golite062009
  • catalytic activity
    		•  2.50389926428623 bayes_pls_golite062009
  • oxidized base lesion DNA N-glycosylase activity
    		•  1.80199518353554 bayes_pls_golite062009
  • alkylbase DNA N-glycosylase activity
    		•  1.75218522602775 bayes_pls_golite062009
  • hydrolase activity
    		•  1.39000450534744 bayes_pls_golite062009
  • DNA-3-methyladenine glycosylase I activity
    		•  1.14337995879633 bayes_pls_golite062009
  • oxidized purine base lesion DNA N-glycosylase activity
    		•  0.473206156100251 bayes_pls_golite062009
  • uracil DNA N-glycosylase activity
    		•  0.29478804124408 bayes_pls_golite062009
  • oxidized pyrimidine base lesion DNA N-glycosylase activity
    		•  0.253198605718519 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.94

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle