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View Structure Prediction Details

Protein: NTH1_ARATH
Organism: Arabidopsis thaliana
Length: 379 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for NTH1_ARATH.

Description E-value Query
Range
Subject
Range
gi|21537257 - gi|21537257|gb|AAM61598.1| putative endonuclease [Arabidopsis thaliana]
361.0 [0..1] [379..1]

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Predicted Domain #1
Region A:
Residues: [1-135]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MILLVNGGAA TSIHPNAARF YRIGTMSRQI HGAVSSSKHI SLKTQHPLSD SNSELAYGAS  60
   61 GSETRVYTRK KRLKQEPFEP LEKYSGKGVN THKLCGLPDI EDFAYKKTIG SPSSSRSTET 120
  121 SITVTSVKTA GYPPE

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [136-379]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NWVEVLEGIR QMRSSEDAPV DSMGCDKAGS FLPPTERRFA VLLGALLSSQ TKDQVNNAAI  60
   61 HRLHQNGLLT PEAVDKADES TIKELIYPVG FYTRKATYMK KIARICLVKY DGDIPSSLDD 120
  121 LLSLPGIGPK MAHLILHIAW NDVQGICVDT HVHRICNRLG WVSRPGTKQK TTSPEETRVA 180
  181 LQQWLPKEEW VAINPLLVGF GQMICTPIRP RCEACSVSKL CPAAFKETSS PSSKLKKSNR 240
  241 SKEP

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 56.0
Match: 1ornA
Description: Endonuclease III
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
DNA N-glycosylase activity 4.08559331236111 bayes_pls_golite062009
hydrolase activity, hydrolyzing N-glycosyl compounds 3.73234184319832 bayes_pls_golite062009
DNA-(apurinic or apyrimidinic site) lyase activity 3.12421941323765 bayes_pls_golite062009
hydrolase activity, acting on glycosyl bonds 2.54759386266723 bayes_pls_golite062009
catalytic activity 2.50389926428623 bayes_pls_golite062009
oxidized base lesion DNA N-glycosylase activity 1.80199518353554 bayes_pls_golite062009
alkylbase DNA N-glycosylase activity 1.75218522602775 bayes_pls_golite062009
hydrolase activity 1.39000450534744 bayes_pls_golite062009
DNA-3-methyladenine glycosylase I activity 1.14337995879633 bayes_pls_golite062009
oxidized purine base lesion DNA N-glycosylase activity 0.473206156100251 bayes_pls_golite062009
uracil DNA N-glycosylase activity 0.29478804124408 bayes_pls_golite062009
oxidized pyrimidine base lesion DNA N-glycosylase activity 0.253198605718519 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle