Protein Overview: ODP21_ARATH

General Information:
Name(s) found:	ODP21_ARATH [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|4678949\|emb\|CAB41340.1\| dihydrolipoamide S-acetyltransferase precursor [Arabidopsis thaliana] [NCBI NR] gi\|15231159\|ref\|NP_190788.1\| LTA3; ATP binding / dihydrolipoyllysine-residue acetyltransferase [Arabidopsis thaliana] [NCBI NR] gi\|117940179\|sp\|Q0WQF7.2\|OPD21_ARATH RecName: Full=Dihydrolipoyllysine-residue acetyltransferase component 1 of pyruvate dehydrogenase complex, mitochondrial; AltName: Full=Pyruvate dehydrogenase complex E2 subunit 1; Short=PDC-E2; Short=PDCE2; Short=E2; [NCBI NR] pir\|\|T49099 dihydrolipoamide S-acetyltransferase precursor - Arabidopsis thaliana [NCBI NR] Dihydrolipoyllysine-residue acetyltransferase component 1 of pyruvate dehydrogenase complex, mitochondrial OS=Arabidopsis thaliana GN=LTA3 PE=1 SV=2 [Swiss-Prot] Dihydrolipoyllysine-residue acetyltransferase component 1 of pyruvate dehydrogenase complex, mitochondrial OS=Arabidopsis thaliana GN=LTA3 PE=2 SV=2 [Swiss-Prot] (Q9SUY5) Dihydrolipoamide S-acetyltransferase [athaliana3702.FASTAC.txt] dihydrolipoamide S-acetyltransferase precursor [Arabidopsis thaliana]gi\|11257430\|pir\|\|T49099 dihydrolipoamide S-acetyltransferase precursor - Arabidopsis thalianagi\|15231159\|ref\|NP_190788.1\| dihydrolipoamide S-acetyltransferase, putative [Arabidopsis th [nrdb_11152004_Chlamydomonas] Tax_Id=3702 Dihydrolipoamide S-acetyltransferase [EBI-IPI_Arabidopsis_3.11_12-06-2005_reversed.fasta] \| Symbols: LTA3 \| LTA3 (Dihydrolipoamide S-acetyltransferase 3); dihydrolipoyllysine-residue acetyltransferase \| chr3:19371295-19377069 FORWARD [TAIR_Arabidopsis_na_04-12-2008_con_reversed.fasta] Dihydrolipoyllysine-residue acetyltransferase component 1 of pyruvate dehydrogenase complex, mitochondrial precursor (Pyruvate dehydrogenase complex E2 subunit 1) (PDCE2) (E2) (Dihydrolipoamide S-acetyltransferase component 1 of pyruvate dehydrogenase com [nr-271106-contam.fasta] LTA3; acyltransferase/ dihydrolipoyllysine-residue acetyltransferase/ protein binding [Arabidopsis thaliana] [nr-271106-contam.fasta] dihydrolipoamide S-acetyltransferase precursor [Arabidopsis thaliana] [nr-271106-contam.fasta] \| Symbols: LTA3 \| Dihydrolipoamide acetyltransferase, long form protein \| chr3:19360317-19366091 FORWARD LENGTH=637 [TAIR_A_Thaliana_10_12-14-2010_reversed.fasta]
Organism:	Arabidopsis thaliana
Length:	637 amino acids
Gene Ontology:
Cellular Component:	mitochondrion [IDA]
Biological Process:	metabolic process [IEA] pyruvate metabolic process [IEA]
Molecular Function:	ATP binding [IDA] dihydrolipoyllysine-residue acetyltransferase activity [ISS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVLPLFRRAA IARTSSLLRA RLFAPASEFH SRFSNGLYHL DDKISSSNGV RSASIDLITR  60
   61 MDDSSPKPIL RFGVQNFSST GPISQTVLAM PALSPTMSHG NVVKWMKKEG DKVEVGDVLC 120
  121 EIETDKATVE FESQEEGFLA KILVTEGSKD IPVNEPIAIM VEEEDDIKNV PATIEGGRDG 180
  181 KEETSAHQVM KPDESTQQKS SIQPDASDLP PHVVLEMPAL SPTMNQGNIA KWWKKEGDKI 240
  241 EVGDVIGEIE TDKATLEFES LEEGYLAKIL IPEGSKDVAV GKPIALIVED AESIEAIKSS 300
  301 SAGSSEVDTV KEVPDSVVDK PTERKAGFTK ISPAAKLLIL EHGLEASSIE ASGPYGTLLK 360
  361 SDVVAAIASG KASKSSASTK KKQPSKETPS KSSSTSKPSV TQSDNNYEDF PNSQIRKIIA 420
  421 KRLLESKQKI PHLYLQSDVV LDPLLAFRKE LQENHGVKVS VNDIVIKAVA VALRNVRQAN 480
  481 AFWDAEKGDI VMCDSVDISI AVATEKGLMT PIIKNADQKS ISAISLEVKE LAQKARSGKL 540
  541 APHEFQGGTF SISNLGMYPV DNFCAIINPP QAGILAVGRG NKVVEPVIGL DGIEKPSVVT 600
  601 KMNVTLSADH RIFDGQVGAS FMSELRSNFE DVRRLLL

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Searching the YRC Public Image Repository, found results:

Currently showing to of results.

[View Search in the YRC Public Image Repository]

Searching the YRC Public Image Repository, found no results.

Ginzu Version Information

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

Gene Ontology predictions

No functions predicted.

Term	Confidence	Notes
S-succinyltransferase activity	10.0778678835755	bayes_pls_golite062009
dihydrolipoyllysine-residue succinyltransferase activity	10.0778678835755	bayes_pls_golite062009
dihydrolipoyllysine-residue acetyltransferase activity	9.65061123545754	bayes_pls_golite062009
dihydrolipoamide S-acyltransferase activity	9.64995677986911	bayes_pls_golite062009
S-acetyltransferase activity	9.49696044977584	bayes_pls_golite062009
S-acyltransferase activity	8.45313874919036	bayes_pls_golite062009
pyruvate dehydrogenase activity	8.17557182322815	bayes_pls_golite062009
transferase activity, transferring acyl groups other than amino-acyl groups	6.86215901871647	bayes_pls_golite062009
acyltransferase activity	6.83977352892719	bayes_pls_golite062009
succinyltransferase activity	6.58826720904067	bayes_pls_golite062009
pyruvate dehydrogenase (acetyl-transferring) activity	6.40483178382327	bayes_pls_golite062009
acetyltransferase activity	6.08159176722072	bayes_pls_golite062009
oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor	5.93985773477717	bayes_pls_golite062009
transferase activity, transferring acyl groups	4.60481199262496	bayes_pls_golite062009
carnitine O-acyltransferase activity	2.87366177129153	bayes_pls_golite062009
oxidoreductase activity, acting on the aldehyde or oxo group of donors	2.54513901872655	bayes_pls_golite062009
catalytic activity	1.51562638409295	bayes_pls_golite062009
O-acyltransferase activity	1.33852311685118	bayes_pls_golite062009
O-palmitoyltransferase activity	1.22729402619659	bayes_pls_golite062009
carnitine O-palmitoyltransferase activity	1.22729402619659	bayes_pls_golite062009
transferase activity	1.08341671157927	bayes_pls_golite062009
carnitine O-acetyltransferase activity	1.00868366840715	bayes_pls_golite062009
alpha-ketoacid dehydrogenase activity	0.79135670574828	bayes_pls_golite062009
O-acetyltransferase activity	0.54660034926676	bayes_pls_golite062009
binding	0.406715755927461	bayes_pls_golite062009
protein binding	0.127298422545208	bayes_pls_golite062009

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.57

Source: Reynolds et al. (2008)

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..206]	PSI-BLAST	17.09691	Crystal structure of the PDK3-L2 complex
2	View Details	[207..288]	PSI-BLAST	12.30103	No description for 2d5dA was found.
3	View Details	[289..399]	PSI-BLAST	24.522879	The crystal structure of dihydrolipoamide dehydrogenase and dihydrolipoamide dehydrogenase-binding protein (didomain) subcomplex of human pyruvate dehydrogenase complex.
4	View Details	[400..637]	PSI-BLAST	81.69897	Dihydrolipoamide succinyltransferase

Protein Overview: ODP21_ARATH

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: