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View Structure Prediction Details

Protein: ODP21_ARATH
Organism: Arabidopsis thaliana
Length: 637 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ODP21_ARATH.

Description E-value Query
Range		 Subject
Range
gi|5881965 - gi|5881965|gb|AAD55140.1|AF066080_1 dihydrolipoamide S-acetyltransferase [Arabidopsis thaliana]
 535.0 [0..1] [637..1]

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Predicted Domain #1
Region A:
Residues: [1-206] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVLPLFRRAA IARTSSLLRA RLFAPASEFH SRFSNGLYHL DDKISSSNGV RSASIDLITR  60
   61 MDDSSPKPIL RFGVQNFSST GPISQTVLAM PALSPTMSHG NVVKWMKKEG DKVEVGDVLC 120
  121 EIETDKATVE FESQEEGFLA KILVTEGSKD IPVNEPIAIM VEEEDDIKNV PATIEGGRDG 180
  181 KEETSAHQVM KPDESTQQKS SIQPDA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 17.09691
Match: 1y8nB
Description: Crystal structure of the PDK3-L2 complex
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [207-288] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SDLPPHVVLE MPALSPTMNQ GNIAKWWKKE GDKIEVGDVI GEIETDKATL EFESLEEGYL  60
   61 AKILIPEGSK DVAVGKPIAL IV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 12.30103
Match: 2d5dA
Description: No description for 2d5dA was found.

Predicted Domain #3
Region A:
Residues: [289-399] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EDAESIEAIK SSSAGSSEVD TVKEVPDSVV DKPTERKAGF TKISPAAKLL ILEHGLEASS  60
   61 IEASGPYGTL LKSDVVAAIA SGKASKSSAS TKKKQPSKET PSKSSSTSKP S

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 24.522879
Match: 1zy8K
Description: The crystal structure of dihydrolipoamide dehydrogenase and dihydrolipoamide dehydrogenase-binding protein (didomain) subcomplex of human pyruvate dehydrogenase complex.
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [400-637] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VTQSDNNYED FPNSQIRKII AKRLLESKQK IPHLYLQSDV VLDPLLAFRK ELQENHGVKV  60
   61 SVNDIVIKAV AVALRNVRQA NAFWDAEKGD IVMCDSVDIS IAVATEKGLM TPIIKNADQK 120
  121 SISAISLEVK ELAQKARSGK LAPHEFQGGT FSISNLGMYP VDNFCAIINP PQAGILAVGR 180
  181 GNKVVEPVIG LDGIEKPSVV TKMNVTLSAD HRIFDGQVGA SFMSELRSNF EDVRRLLL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 81.69897
Match: 1c4tA
Description: Dihydrolipoamide succinyltransferase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
S-succinyltransferase activity 10.0778678835755 bayes_pls_golite062009
dihydrolipoyllysine-residue succinyltransferase activity 10.0778678835755 bayes_pls_golite062009
dihydrolipoyllysine-residue acetyltransferase activity 9.65061123545754 bayes_pls_golite062009
dihydrolipoamide S-acyltransferase activity 9.64995677986911 bayes_pls_golite062009
S-acetyltransferase activity 9.49696044977584 bayes_pls_golite062009
S-acyltransferase activity 8.45313874919036 bayes_pls_golite062009
pyruvate dehydrogenase activity 8.17557182322815 bayes_pls_golite062009
transferase activity, transferring acyl groups other than amino-acyl groups 6.86215901871647 bayes_pls_golite062009
acyltransferase activity 6.83977352892719 bayes_pls_golite062009
succinyltransferase activity 6.58826720904067 bayes_pls_golite062009
pyruvate dehydrogenase (acetyl-transferring) activity 6.40483178382327 bayes_pls_golite062009
acetyltransferase activity 6.08159176722072 bayes_pls_golite062009
oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor 5.93985773477717 bayes_pls_golite062009
transferase activity, transferring acyl groups 4.60481199262496 bayes_pls_golite062009
carnitine O-acyltransferase activity 2.87366177129153 bayes_pls_golite062009
oxidoreductase activity, acting on the aldehyde or oxo group of donors 2.54513901872655 bayes_pls_golite062009
catalytic activity 1.51562638409295 bayes_pls_golite062009
O-acyltransferase activity 1.33852311685118 bayes_pls_golite062009
O-palmitoyltransferase activity 1.22729402619659 bayes_pls_golite062009
carnitine O-palmitoyltransferase activity 1.22729402619659 bayes_pls_golite062009
transferase activity 1.08341671157927 bayes_pls_golite062009
carnitine O-acetyltransferase activity 1.00868366840715 bayes_pls_golite062009
alpha-ketoacid dehydrogenase activity 0.79135670574828 bayes_pls_golite062009
O-acetyltransferase activity 0.54660034926676 bayes_pls_golite062009
binding 0.406715755927461 bayes_pls_golite062009
protein binding 0.127298422545208 bayes_pls_golite062009
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle