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Protein Overview: ODP21_ARATH

General Information:
Name(s) found: ODP21_ARATH [Swiss-Prot]
Description(s) found:
Found 14 descriptions.
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  • Dihydrolipoyllysine-residue acetyltransferase component 1 of pyruvate dehydrogenase complex, mitochondrial OS=Arabidopsis thaliana GN=LTA3 PE=2 SV=2 [Swiss-Prot]
    • Organism: Arabidopsis thaliana
    Length: 637 amino acids

    Gene Ontology:
    Cellular Component: mitochondrion [IDA]
    Biological Process: metabolic process [IEA]
    pyruvate metabolic process [IEA]
    Molecular Function: ATP binding [IDA]
    dihydrolipoyllysine-residue acetyltransferase activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVLPLFRRAA IARTSSLLRA RLFAPASEFH SRFSNGLYHL DDKISSSNGV RSASIDLITR  60
   61 MDDSSPKPIL RFGVQNFSST GPISQTVLAM PALSPTMSHG NVVKWMKKEG DKVEVGDVLC 120
  121 EIETDKATVE FESQEEGFLA KILVTEGSKD IPVNEPIAIM VEEEDDIKNV PATIEGGRDG 180
  181 KEETSAHQVM KPDESTQQKS SIQPDASDLP PHVVLEMPAL SPTMNQGNIA KWWKKEGDKI 240
  241 EVGDVIGEIE TDKATLEFES LEEGYLAKIL IPEGSKDVAV GKPIALIVED AESIEAIKSS 300
  301 SAGSSEVDTV KEVPDSVVDK PTERKAGFTK ISPAAKLLIL EHGLEASSIE ASGPYGTLLK 360
  361 SDVVAAIASG KASKSSASTK KKQPSKETPS KSSSTSKPSV TQSDNNYEDF PNSQIRKIIA 420
  421 KRLLESKQKI PHLYLQSDVV LDPLLAFRKE LQENHGVKVS VNDIVIKAVA VALRNVRQAN 480
  481 AFWDAEKGDI VMCDSVDISI AVATEKGLMT PIIKNADQKS ISAISLEVKE LAQKARSGKL 540
  541 APHEFQGGTF SISNLGMYPV DNFCAIINPP QAGILAVGRG NKVVEPVIGL DGIEKPSVVT 600
  601 KMNVTLSADH RIFDGQVGAS FMSELRSNFE DVRRLLL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..206] PSI-BLAST 17.09691 Crystal structure of the PDK3-L2 complex
    2 View Details [207..288] PSI-BLAST 12.30103 No description for 2d5dA was found.
    3 View Details [289..399] PSI-BLAST 24.522879 The crystal structure of dihydrolipoamide dehydrogenase and dihydrolipoamide dehydrogenase-binding protein (didomain) subcomplex of human pyruvate dehydrogenase complex.
    4 View Details [400..637] PSI-BLAST 81.69897 Dihydrolipoamide succinyltransferase

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3 No functions predicted.
    4
    Term Confidence Notes
  • S-succinyltransferase activity
    		•  10.0778678835755 bayes_pls_golite062009
  • dihydrolipoyllysine-residue succinyltransferase activity
    		•  10.0778678835755 bayes_pls_golite062009
  • dihydrolipoyllysine-residue acetyltransferase activity
    		•  9.65061123545754 bayes_pls_golite062009
  • dihydrolipoamide S-acyltransferase activity
    		•  9.64995677986911 bayes_pls_golite062009
  • S-acetyltransferase activity
    		•  9.49696044977584 bayes_pls_golite062009
  • S-acyltransferase activity
    		•  8.45313874919036 bayes_pls_golite062009
  • pyruvate dehydrogenase activity
    		•  8.17557182322815 bayes_pls_golite062009
  • transferase activity, transferring acyl groups other than amino-acyl groups
    		•  6.86215901871647 bayes_pls_golite062009
  • acyltransferase activity
    		•  6.83977352892719 bayes_pls_golite062009
  • succinyltransferase activity
    		•  6.58826720904067 bayes_pls_golite062009
  • pyruvate dehydrogenase (acetyl-transferring) activity
    		•  6.40483178382327 bayes_pls_golite062009
  • acetyltransferase activity
    		•  6.08159176722072 bayes_pls_golite062009
  • oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
    		•  5.93985773477717 bayes_pls_golite062009
  • transferase activity, transferring acyl groups
    		•  4.60481199262496 bayes_pls_golite062009
  • carnitine O-acyltransferase activity
    		•  2.87366177129153 bayes_pls_golite062009
  • oxidoreductase activity, acting on the aldehyde or oxo group of donors
    		•  2.54513901872655 bayes_pls_golite062009
  • catalytic activity
    		•  1.51562638409295 bayes_pls_golite062009
  • O-acyltransferase activity
    		•  1.33852311685118 bayes_pls_golite062009
  • O-palmitoyltransferase activity
    		•  1.22729402619659 bayes_pls_golite062009
  • carnitine O-palmitoyltransferase activity
    		•  1.22729402619659 bayes_pls_golite062009
  • transferase activity
    		•  1.08341671157927 bayes_pls_golite062009
  • carnitine O-acetyltransferase activity
    		•  1.00868366840715 bayes_pls_golite062009
  • alpha-ketoacid dehydrogenase activity
    		•  0.79135670574828 bayes_pls_golite062009
  • O-acetyltransferase activity
    		•  0.54660034926676 bayes_pls_golite062009
  • binding
    		•  0.406715755927461 bayes_pls_golite062009
  • protein binding
    		•  0.127298422545208 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.57

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle