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Protein Overview: RTL2_ARATH

General Information:
Name(s) found: RTL2_ARATH [Swiss-Prot]
Description(s) found:
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  • gi|9294562|dbj|BAB02825.1| unnamed protein product [Arabidopsis thaliana] [NCBI NR]
  • gi|18402610|ref|NP_566661.1| RTL2 (RNASE THREE-LIKE PROTEIN 2); double-stranded RNA binding / ribonuclease III [Arabidopsis thaliana] [NCBI NR]
  • Ribonuclease 3-like protein 2 OS=Arabidopsis thaliana GN=RTL2 PE=1 SV=1 [Swiss-Prot]
  • (Q9LTQ0) Similarity to CAF protein [athaliana3702.FASTAC.txt]
  • unnamed protein product [Arabidopsis thaliana]gi|18402610|ref|NP_566661.1| ribonuclease III family protein [Arabidopsis thaliana] [nrdb_11152004_Chlamydomonas]
  • Tax_Id=3702 Ribonuclease III family protein [EBI-IPI_Arabidopsis_3.11_12-06-2005_reversed.fasta]
  • | Symbols: RTL2 | RTL2 (RNASE THREE-LIKE PROTEIN 2); double-stranded RNA binding / ribonuclease III. | chr3:7119377-7120901 REVERSE [TAIR_Arabidopsis_na_04-12-2008_con_reversed.fasta]
  • unnamed protein product [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • RNA binding / double-stranded RNA binding / ribonuclease III [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • | Symbols: RTL2, ATRTL2 | RNAse THREE-like protein 2 | chr3:7119371-7120895 REVERSE LENGTH=391 [TAIR_A_Thaliana_10_12-14-2010_reversed.fasta]
    • Organism: Arabidopsis thaliana
    Length: 391 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDA]
    cytoplasm [IDA]
    Biological Process: RNA processing [IEA]
    Molecular Function: ribonuclease III activity [IMP][ISS]
    double-stranded RNA binding [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDHSISPEYN FPAITRCSLS NSLPHRPPSP LPSSADIHRF YNSLSPSAPS VPVSSEMESM  60
   61 EAVEKILNYK FSNKSLLKEA ITHTSCTDFP SYERLEFIGD SAIGLAISNY LYLTYPSLEP 120
  121 HDLSLLRAAN VSTEKLARVS LNHGLYSFLR RNAPSLDEKV KEFSEAVGKE DDLSVSYGGL 180
  181 VKAPKVLADL FESLAGAVYV DVNFDLQRLW VIFRGLLEPI VTLDDLQKQP QPVSMLFKLC 240
  241 HKHKKRIDIK NWKDGNVSIA VIYLDDELLA SGRAENKDIA RLIAAKEALR KLSEVFPVEM 300
  301 VIDEDSVEIQ LTHAKTKLNE ICLKKKWPKP IYSVEEDRSS VQGKRFVCSA KIKITEEKTL 360
  361 YMKGDEQSKI KKAESSSAYH MIRALRKSHY L

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..303] PSI-BLAST 40.09691 RNase III endonuclease catalytic domain; RNase III, C-terminal domain
    2 View Details [304..391] PSI-BLAST 16.045757 Solution structure of the second dsRBD of TAR RNA-binding protein 2

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • RNA binding
    		•  2.103878681691 bayes_pls_golite062009
  • endoribonuclease activity
    		•  2.02847548000256 bayes_pls_golite062009
  • endonuclease activity
    		•  1.52328576888271 bayes_pls_golite062009
  • binding
    		•  1.36306903445995 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.33734225890407 bayes_pls_golite062009
  • double-stranded RNA binding
    		•  0.80785216315429 bayes_pls_golite062009
  • catalytic activity
    		•  0.328884095744829 bayes_pls_golite062009
  • protein binding
    		•  0.018276859224266 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle