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Protein Overview: TF2H2_ARATH

General Information:
Name(s) found: TF2H2_ARATH [Swiss-Prot]
Description(s) found:
Found 16 descriptions.
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  • General transcription factor IIH subunit 2 OS=Arabidopsis thaliana GN=GTF2H2 PE=1 SV=1 [Swiss-Prot]
    • Organism: Arabidopsis thaliana
    Length: 421 amino acids

    Gene Ontology:
    Cellular Component: holo TFIIH complex [IGI]
    Biological Process: nucleotide-excision repair [IGI]
    regulation of transcription from RNA polymerase II promoter, global [IGI]
    Molecular Function: general RNA polymerase II transcription factor activity [IGI]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSNQRKRSND EREEEDDEDA EGIGEWERAY VDDRSWEELQ EDESGLLRPI DNSAIYHAQY  60
   61 RRRLRMLSAA AAGTRIQKGL IRYLYIVIDF SRAAAEMDFR PSRMAIMAKH VEAFIREFFD 120
  121 QNPLSQIGLV SIKNGVAHTL TDLGGSPETH IKALMGKLEA LGDSSLQNAL ELVHEHLNQV 180
  181 PSYGHREVLI LYSALCTCDP GDIMETIQKC KKSKLRCSVI GLSAEMFICK HLCQETGGLY 240
  241 SVAVDEVHLK DLLLEHAPPP PAIAEFAIAN LIKMGFPQRA AEGSMAICSC HKEVKIGAGY 300
  301 MCPRCKARVC DLPTECTICG LTLVSSPHLA RSYHHLFPIA PFDEVPALSS LNDNRRKLGK 360
  361 SCFGCQQSLI GAGNKPVPCV TCRKCKHYFC LDCDIYIHES LHNCPGCESI HRPKSVSLME 420
  421 E

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..282] PSI-BLAST 14.522879 No description for 2ok5A was found.
    2 View Details [283..421] PSI-BLAST 16.09691 Solution structure of the carboxy-terminal domain of human TFIIH P44 subunit

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • binding
    		•  2.78081530457495 bayes_pls_golite062009
  • protein binding
    		•  1.87564165872234 bayes_pls_golite062009
  • DNA binding
    		•  1.67175195853604 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.66804415166051 bayes_pls_golite062009
  • cell surface binding
    		•  1.100737691234 bayes_pls_golite062009
  • eukaryotic cell surface binding
    		•  0.75976840299626 bayes_pls_golite062009
  • hydrolase activity
    		•  0.713727944323346 bayes_pls_golite062009
  • protein complex binding
    		•  0.68878168136573 bayes_pls_golite062009
  • receptor activity
    		•  0.537407856490475 bayes_pls_golite062009
  • structure-specific DNA binding
    		•  0.450760554291027 bayes_pls_golite062009
  • transmembrane receptor activity
    		•  0.414030020499752 bayes_pls_golite062009
  • protein heterodimerization activity
    		•  0.32921284315242 bayes_pls_golite062009
  • catalytic activity
    		•  0.252597265474331 bayes_pls_golite062009
  • heparin binding
    		•  0.0497639742848703 bayes_pls_golite062009
  • complement binding
    		•  0.0415669963240149 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle