Protein Overview: TRPC_ARATH

General Information:
Name(s) found:	TRPC_ARATH [Swiss-Prot]
Description(s) found: Found 16 descriptions. SHOW ALL	Indole-3-glycerol phosphate synthase, chloroplastic OS=Arabidopsis thaliana GN=IGPS PE=1 SV=2 [Swiss-Prot]
Organism:	Arabidopsis thaliana
Length:	402 amino acids
Gene Ontology:
Cellular Component:	chloroplast [IDA][ISS]
Biological Process:	tryptophan biosynthetic process [TAS]
Molecular Function:	indole-3-glycerol-phosphate synthase activity [IGI] copper ion binding [IDA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEGLVPVQRL PIKVASPSLY RCNNSVSIRR SISGFAMDRK INFRAPSQFS IRAQQSDLKE  60
   61 SLAVSSSSVE DKGNVLRIKE WEVEMYQEEL AISQGIRIRR KPPSKAPLGY SGPFELRLHN 120
  121 NDADSPRNIL EEITWYKDVE VSRMKELNPL DVLKKAVEDA PPTRDFVGAL RMAHKRTGFP 180
  181 GLIAEVKKAS PSRGILKENF DPVEIAQAYE KGGAACLSVL TDQKYFQGGF ENLEAIRSAG 240
  241 VKCPLLCKEF VVDPWQIYYA RTKGADAVLL IAAVLADLEI TFLLKICKKL SLAALVEVHD 300
  301 EREMGRVLGI EGIELVGINN RSLETFEVDI SNTKKLLEGE HGRQIRERDM IVVGESGLFT 360
  361 PDDIAYVQAA GVKAVLVGES IVKQNDPEKG IAGLFGRNIS HT

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Microscopy / Localization Data

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No microscopy data found in the PDR for this protein.

Protein Structure Data

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[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..117]	PSI-BLAST	26.09691	Anthranilate synthase GAT subunit, TrpG
2	View Details	[118..402]	PSI-BLAST	53.522879	THREE-DIMENSIONAL STRUCTURE OF THE BIFUNCTIONAL ENZYME PHOSPHORIBOSYLANTHRANILATE ISOMERASE: INDOLEGLYCEROLPHOSPHATE SYNTHASE FROM ESCHERICHIA COLI REFINED AT 2.0 ANGSTROMS RESOLUTION

Functions predicted (by domain):

#

Gene Ontology predictions

1

Term	Confidence	Notes
anthranilate synthase activity	2.75585393226063	bayes_pls_golite062009
oxo-acid-lyase activity	1.86066620418318	bayes_pls_golite062009
catalytic activity	1.67435536171189	bayes_pls_golite062009
ligase activity	1.25010133890527	bayes_pls_golite062009
carbon-carbon lyase activity	0.71617600377795	bayes_pls_golite062009
imidazoleglycerol-phosphate synthase activity	0.52616972602552	bayes_pls_golite062009
carbon-nitrogen ligase activity, with glutamine as amido-N-donor	0.113939560975652	bayes_pls_golite062009
ligase activity, forming carbon-nitrogen bonds	0.100283432019111	bayes_pls_golite062009

2

Term	Confidence	Notes
tryptophan synthase activity	3.15663465352598	bayes_pls_golite062009
indole-3-glycerol-phosphate synthase activity	3.12120866545322	bayes_pls_golite062009
catalytic activity	2.81275055404078	bayes_pls_golite062009
phosphoribosylanthranilate isomerase activity	2.655130814615	bayes_pls_golite062009
carbon-carbon lyase activity	2.44001937916931	bayes_pls_golite062009
carboxy-lyase activity	1.80978905789979	bayes_pls_golite062009
lyase activity	0.9228652996943	bayes_pls_golite062009
imidazoleglycerol-phosphate synthase activity	0.82314869965119	bayes_pls_golite062009
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase activity	0.302746738903759	bayes_pls_golite062009
isomerase activity	0.14149405165663	bayes_pls_golite062009

Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

Philius Transmembrane Prediction:

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.98

Source: Reynolds et al. (2008)

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