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Catalysis of the nonhydrolytic addition or removal of a carboxyl group to or from a compound. Catalysis of the cleavage of C-C bonds by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond. Catalysis of the reaction: 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate = 1-(indol-3-yl)glycerol 3-phosphate + CO2 + H2O.

View Gene Ontology (GO) Term

GO TERM SUMMARY

Name: indole-3-glycerol-phosphate synthase activity
Acc: GO:0004425
Aspect: Molecular Function
Desc: Catalysis of the reaction: 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate = 1-(indol-3-yl)glycerol 3-phosphate + CO2 + H2O.
Synonyms:
  • indoleglycerol phosphate synthase activity
  • indoleglycerol phosphate synthetase activity
  • indole-3-glycerophosphate synthase activity
  • 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose-5-phosphate carboxy-lyase (cyclizing)
  • 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose-5-phosphate carboxy-lyase [cyclizing; 1-C-(3-indolyl)-glycerol-3-phosphate-forming]
Proteins in PDR annotated with:
   This term: 15 [Search]
   Term or descendants: 15 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0004425 - indole-3-glycerol-phosphate synthase activity (interactive image map)

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