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Protein Overview: UGE2_ARATH

General Information:
Name(s) found: UGE2_ARATH [Swiss-Prot]
Description(s) found:
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  • pir||T08911 UDPglucose 4-epimerase (EC 5.1.3.2) T32A16.90 - Arabidopsis thaliana [NCBI NR]
  • gi|7269241|emb|CAB81310.1| UDPglucose 4-epimerase-like protein [Arabidopsis thaliana] [NCBI NR]
  • gi|4972096|emb|CAB43892.1| UDPglucose 4-epimerase-like protein [Arabidopsis thaliana] [NCBI NR]
  • gi|30793827|gb|AAP40366.1| putative UDPglucose 4-epimerase [Arabidopsis thaliana] [NCBI NR]
  • gi|26452462|dbj|BAC43316.1| putative UDPglucose 4-epimerase [Arabidopsis thaliana] [NCBI NR]
  • gi|15236663|ref|NP_194123.1| UGE2 (UDP-D-glucose/UDP-D-galactose 4-epimerase 2); UDP-glucose 4-epimerase/ protein dimerization [Arabidopsis thaliana] [NCBI NR]
  • gi|11386854|sp|Q9T0A7.1|GALE3_ARATH RecName: Full=UDP-glucose 4-epimerase 3; AltName: Full=UDP-galactose 4-epimerase 3; AltName: Full=Galactowaldenase 3 [NCBI NR]
  • UDP-glucose 4-epimerase 2 OS=Arabidopsis thaliana GN=UGE2 PE=1 SV=1 [Swiss-Prot]
  • UDP-glucose 4-epimerase 3 OS=Arabidopsis thaliana GN=At4g23920 PE=2 SV=1 [Swiss-Prot]
  • (Q9T0A7) Probable UDP-glucose 4-epimerase At4g23920 (EC 5.1.3.2) (Galactowaldenase) (UDP-galactose 4-epimerase) [Swiss-Prot]
  • putative UDPglucose 4-epimerase [Arabidopsis thaliana]gi|26452462|dbj|BAC43316.1| putative UDPglucose 4-epimerase [Arabidopsis thaliana]gi|7269241|emb|CAB81310.1| UDPglucose 4-epimerase-like protein [Arabidopsis thaliana]gi|4972096|emb|CAB43892.1| UDPg [nrdb_11152004_Chlamydomonas]
  • Tax_Id=3702 Probable UDP-glucose 4-epimerase At4g23920 [EBI-IPI_Arabidopsis_3.11_12-06-2005_reversed.fasta]
  • | Symbols: UGE2 | UGE2 (UDP-D-GLUCOSE/UDP-D-GALACTOSE 4-EPIMERASE 2); UDP-glucose 4-epimerase/ protein dimerization | chr4:12431426-12433676 FORWARD [TAIR_Arabidopsis_na_04-12-2008_con_reversed.fasta]
  • UDPglucose 4-epimerase-like protein [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • Probable UDP-glucose 4-epimerase At4g23920 (Galactowaldenase) (UDP-galactose 4-epimerase) [nr-271106-contam.fasta]
  • putative UDPglucose 4-epimerase [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • NAD binding / UDP-glucose 4-epimerase/ catalytic [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • | Symbols: UGE2, ATUGE2 | UDP-D-glucose/UDP-D-galactose 4-epimerase 2 | chr4:12431416-12433666 FORWARD LENGTH=350 [TAIR_A_Thaliana_10_12-14-2010_reversed.fasta]
    • Organism: Arabidopsis thaliana
    Length: 350 amino acids

    Gene Ontology:
    Cellular Component: cytosol [IDA]
    Biological Process: cell wall biogenesis [IMP]
    Molecular Function: UDP-glucose 4-epimerase activity [IDA][IGI]
    protein dimerization activity [IPI]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAKSVLVTGG AGYIGSHTVL QLLEGGYSAV VVDNYDNSSA ASLQRVKKLA GENGNRLSFH  60
   61 QVDLRDRPAL EKIFSETKFD AVIHFAGLKA VGESVEKPLL YYNNNIVGTV TLLEVMAQYG 120
  121 CKNLVFSSSA TVYGWPKEVP CTEESPISAT NPYGRTKLFI EEICRDVHRS DSEWKIILLR 180
  181 YFNPVGAHPS GYIGEDPLGV PNNLMPYVQQ VAVGRRPHLT VFGTDYKTKD GTGVRDYIHV 240
  241 MDLADGHIAA LRKLDDLKIS CEVYNLGTGN GTSVLEMVAA FEKASGKKIP LVMAGRRPGD 300
  301 AEVVYASTEK AERELNWKAK NGIEEMCRDL WNWASNNPYG YNSSSNGSSS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..350] PSI-BLAST 92.30103 Uridine diphosphogalactose-4-epimerase (UDP-galactose 4-epimerase)

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • steroid dehydrogenase activity
    		•  3.70115036051018 bayes_pls_golite062009
  • steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
    		•  3.56748749904419 bayes_pls_golite062009
  • UDP-glucose 4-epimerase activity
    		•  2.13934644118967 bayes_pls_golite062009
  • catalytic activity
    		•  1.79741889688267 bayes_pls_golite062009
  • oxidoreductase activity, acting on CH-OH group of donors
    		•  1.03956654822048 bayes_pls_golite062009
  • C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity
    		•  1.03845584151228 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.868888700854563 bayes_pls_golite062009
  • binding
    		•  0.835119783772935 bayes_pls_golite062009
  • oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
    		•  0.82673050487418 bayes_pls_golite062009
  • DNA binding
    		•  0.790382977752475 bayes_pls_golite062009
  • 3-alpha(17-beta)-hydroxysteroid dehydrogenase (NAD+) activity
    		•  0.744959961067911 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.613310508772122 bayes_pls_golite062009
  • retinol dehydrogenase activity
    		•  0.48259320361048 bayes_pls_golite062009
  • transcription factor activity
    		•  0.11102650759187 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.67

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle