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Protein Overview: UGE1_ARATH

General Information:
Name(s) found: UGE1_ARATH [Swiss-Prot]
Description(s) found:
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  • gi|8698725|gb|AAF78483.1|AC012187_3 Strong similarity to UDPglucose 4-epimerase from Arabidopsis thaliana gi|2129759 and is a member of the NAD dependent Epimerase/Dehydratase PF|01370 family. ESTs gb|AI100184, gb|T22969, gb|T22968, gb|H76416, gb|AI99880 [NCBI NR]
  • pir||B86261 UDPglucose 4-epimerase (EC 5.1.3.2) [imported] - Arabidopsis thaliana [NCBI NR]
  • gi|23197648|gb|AAN15351.1| uridine diphosphate glucose epimerase [Arabidopsis thaliana] [NCBI NR]
  • gi|21539429|gb|AAM53267.1| uridine diphosphate glucose epimerase [Arabidopsis thaliana] [NCBI NR]
  • gi|15809880|gb|AAL06868.1| At1g12780/F13K23_21 [Arabidopsis thaliana] [NCBI NR]
  • gi|15222072|ref|NP_172738.1| UGE1 (UDP-D-glucose/UDP-D-galactose 4-epimerase 1); UDP-glucose 4-epimerase/ protein dimerization [Arabidopsis thaliana] [NCBI NR]
  • gi|12643760|sp|Q42605.2|GALE1_ARATH RecName: Full=UDP-glucose 4-epimerase 1; AltName: Full=UDP-galactose 4-epimerase 1; AltName: Full=Galactowaldenase 1 [NCBI NR]
  • gi|12248021|gb|AAG50102.1|AF334724_1 putative uridine diphosphate glucose epimerase [Arabidopsis thaliana] [NCBI NR]
  • Bifunctional UDP-glucose 4-epimerase and UDP-xylose 4-epimerase 1 OS=Arabidopsis thaliana GN=UGE1 PE=1 SV=2 [Swiss-Prot]
  • UDP-glucose 4-epimerase 1 OS=Arabidopsis thaliana GN=At1g12780 PE=1 SV=2 [Swiss-Prot]
  • (Q42605) UDP-glucose 4-epimerase (EC 5.1.3.2) (Galactowaldenase) (UDP-galactose 4-epimerase) [Swiss-Prot]
  • putative uridine diphosphate glucose epimerase [Arabidopsis thaliana]gi|23197648|gb|AAN15351.1| uridine diphosphate glucose epimerase [Arabidopsis thaliana]gi|21539429|gb|AAM53267.1| uridine diphosphate glucose epimerase [Arabidopsis thaliana]gi|869872 [nrdb_11152004_Chlamydomonas]
  • Tax_Id=3702 UDP-glucose 4-epimerase [EBI-IPI_Arabidopsis_3.11_12-06-2005_reversed.fasta]
  • | Symbols: UGE1 | UGE1 (UDP-D-GLUCOSE/UDP-D-GALACTOSE 4-EPIMERASE 1); UDP-glucose 4-epimerase/ protein dimerization | chr1:4356122-4358118 REVERSE [TAIR_Arabidopsis_na_04-12-2008_con_reversed.fasta]
  • uridine diphosphate glucose epimerase [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • At1g12780/F13K23_21 [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • putative uridine diphosphate glucose epimerase [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • Strong similarity to UDPglucose 4-epimerase from Arabidopsis thaliana gi|2129759 and is a member of the NAD dependent Epimerase/Dehydratase PF|01370 family. ESTs gb|AI100184, gb|T22969, gb|T22968, gb|H76416, gb|AI998807 come from this gene [nr-271106-contam.fasta]
  • UDP-glucose 4-epimerase [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • UDP-glucose 4-epimerase (Galactowaldenase) (UDP-galactose 4-epimerase) [nr-271106-contam.fasta]
  • | Symbols: UGE1, ATUGE1 | UDP-D-glucose/UDP-D-galactose 4-epimerase 1 | chr1:4356124-4358120 REVERSE LENGTH=351 [TAIR_A_Thaliana_10_12-14-2010_reversed.fasta]
    • Organism: Arabidopsis thaliana
    Length: 351 amino acids

    Gene Ontology:
    Cellular Component: cytosol [IDA][TAS]
    plasma membrane [IDA]
    Biological Process: galactose biosynthetic process [IDA]
    response to stress [IMP]
    Molecular Function: UDP-glucose 4-epimerase activity [IDA][IGI]
    protein dimerization activity [IPI]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGSSVEQNIL VTGGAGFIGT HTVVQLLKDG FKVSIIDNFD NSVIEAVDRV RELVGPDLSK  60
   61 KLDFNLGDLR NKGDIEKLFS KQRFDAVIHF AGLKAVGESV ENPRRYFDNN LVGTINLYET 120
  121 MAKYNCKMMV FSSSATVYGQ PEKIPCMEDF ELKAMNPYGR TKLFLEEIAR DIQKAEPEWR 180
  181 IILLRYFNPV GAHESGSIGE DPKGIPNNLM PYIQQVAVGR LPELNVYGHD YPTEDGSAVR 240
  241 DYIHVMDLAD GHIAALRKLF ADPKIGCTAY NLGTGQGTSV LEMVAAFEKA SGKKIPIKLC 300
  301 PRRSGDATAV YASTEKAEKE LGWKAKYGVD EMCRDQWKWA NNNPWGYQNK L

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..351] PSI-BLAST 94.154902 Uridine diphosphogalactose-4-epimerase (UDP-galactose 4-epimerase)

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • steroid dehydrogenase activity
    		•  3.70115036051018 bayes_pls_golite062009
  • steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
    		•  3.56748749904419 bayes_pls_golite062009
  • UDP-glucose 4-epimerase activity
    		•  2.13934644118967 bayes_pls_golite062009
  • catalytic activity
    		•  1.79741889688267 bayes_pls_golite062009
  • oxidoreductase activity, acting on CH-OH group of donors
    		•  1.03956654822048 bayes_pls_golite062009
  • C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity
    		•  1.03845584151228 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.868888700854563 bayes_pls_golite062009
  • binding
    		•  0.835119783772935 bayes_pls_golite062009
  • oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
    		•  0.82673050487418 bayes_pls_golite062009
  • DNA binding
    		•  0.790382977752475 bayes_pls_golite062009
  • 3-alpha(17-beta)-hydroxysteroid dehydrogenase (NAD+) activity
    		•  0.744959961067911 bayes_pls_golite062009
  • alcohol dehydrogenase (NAD) activity
    		•  0.65743456407889 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.613310508772122 bayes_pls_golite062009
  • retinol dehydrogenase activity
    		•  0.48941662111046 bayes_pls_golite062009
  • transcription factor activity
    		•  0.11102650759187 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.92

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle