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Protein Overview: CNG20_ARATH

General Information:
Name(s) found: CNG20_ARATH [Swiss-Prot]
Description(s) found:
Found 15 descriptions.
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  • Probable cyclic nucleotide-gated ion channel 20, chloroplastic OS=Arabidopsis thaliana GN=CNGC20 PE=2 SV=1 [Swiss-Prot]
    • Organism: Arabidopsis thaliana
    Length: 764 amino acids

    Gene Ontology:
    Cellular Component: chloroplast [IEA]
    membrane [IEA]
    Biological Process: response to nematode [IEP]
    Molecular Function: ion channel activity [ISS]
    calmodulin binding [ISS]
    cyclic nucleotide binding [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MASHNENDDI PMLPISDPSS RTRARAFTSR SRSVSLSNPT SSIEGFDTST VVLGYTGPLR  60
   61 TQRRPPLVQM SGPLTSTRKH EPLFLPHPSS DSVGVSSQPE RYPSFAALEH KNSSEDEFVL 120
  121 KHANLLRSGQ LGMCNDPYCT TCPSYYNRKA AQIPTSRVSA LFDSTFHNAL YDDAKGWARR 180
  181 FASSVNRYLP GIMNPHAKEV QTWTKFFALS CLLAIFIDPL FFFLIKVQEQ NKCIMIDWPM 240
  241 TKAFVAVRSV TDVIFTMNIL LQFRLAYVAR ESTVVGAGQL VSHPKKIALH YLKGKFFLDL 300
  301 FIVMPLPQIL ILWIIPAHLG ASGANYAKNL LRAAVLFQYI PKLYRLLPFL AGQTPTGFIF 360
  361 ESAWANFVIN LLTFMLAGHV VGSCWYLFGL QRVNQCLRNA CGNFGRECQD LIDCGNGNSS 420
  421 VLVRATWKDN ASANACFQED GFPYGIYLKA VNLTNHSNLF TRYSYSLFWG FQQISTLAGN 480
  481 QVPSYFLGEV FFTMGIIGLG LLLFALLIGN MQNFLQALGK RNLEMTLRRR DVEQWMSHRR 540
  541 LPDGIRRRVR EAERFNWAAT RGVNEELLFE NMPDDLQRDI RRHLFKFLKK VRIFSLMDEP 600
  601 ILDAIRERLK QRTYIGSSTV LHRGGLVEKM VFIVRGEMES IGEDGSVLPL YEGDVCGEEL 660
  661 LTWCLERSSV NPDGTRIRMP SKGLLSSRNV RCVTNVEAFS LSVADLEDVT SLFSRFLRSH 720
  721 RVQGAIRYDS PYWRLRAARQ IQVAWRYRRR RLHRLCTPQS SYSL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..177] MSA 2.380996 View MSA. No confident structure predictions are available.
    2 View Details [178..319] FFAS03 1.72 Crystal structure of KvAP-33H1 Fv complex
    3 View Details [320..538] PSI-BLAST 10.154902 Mammalian Shaker Kv1.2 potassium channel- beta subunit complex
    4 View Details [539..590] FFAS03 2.39 No description for 2ptmA was found.
    5 View Details [591..764] PSI-BLAST 12.69897 Solution structure of the cNMP-binding domain from Arabidopsis thaliana cyclic nucleotide-regulated ion channel

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3 No functions predicted.
    4 No functions predicted.
    5
    Term Confidence Notes
  • cyclic nucleotide-gated ion channel activity
    		•  9.28636958853471 bayes_pls_golite062009
  • intracellular cyclic nucleotide activated cation channel activity
    		•  9.28636958853471 bayes_pls_golite062009
  • intracellular cGMP activated cation channel activity
    		•  9.19973076787954 bayes_pls_golite062009
  • intracellular ligand-gated ion channel activity
    		•  8.92326348606261 bayes_pls_golite062009
  • cGMP binding
    		•  7.7575871125398 bayes_pls_golite062009
  • cyclic nucleotide binding
    		•  7.37322432929433 bayes_pls_golite062009
  • GMP binding
    		•  5.49455172024846 bayes_pls_golite062009
  • ligand-gated channel activity
    		•  2.24160712920592 bayes_pls_golite062009
  • ligand-gated ion channel activity
    		•  2.24160712920592 bayes_pls_golite062009
  • metal ion transmembrane transporter activity
    		•  2.1641765932136 bayes_pls_golite062009
  • ion channel activity
    		•  1.99113461395381 bayes_pls_golite062009
  • gated channel activity
    		•  1.96880619620616 bayes_pls_golite062009
  • channel activity
    		•  1.95481941885364 bayes_pls_golite062009
  • passive transmembrane transporter activity
    		•  1.95481941885364 bayes_pls_golite062009
  • substrate-specific channel activity
    		•  1.9532743483506 bayes_pls_golite062009
  • cation channel activity
    		•  1.8875306855156 bayes_pls_golite062009
  • binding
    		•  1.03706428234992 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  0.745476294699195 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  0.646885146396875 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  0.582561336941853 bayes_pls_golite062009
  • protein binding
    		•  0.560659365968498 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  0.489669604147601 bayes_pls_golite062009
  • transporter activity
    		•  0.232363663369302 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  0.209203009093296 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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