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Protein Overview: pab-1

General Information:
Name(s) found: pab-1 / CE36227 [WormBase]
Description(s) found:
Found 17 descriptions.
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  • WBGene00003902 locus:pab-1 status:Partially_confirmed UniProt:Q7K798 protein_id:CAE54916.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 583 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IEALink to PubMed article]
    Biological Process: hermaphrodite genitalia development [IMPLink to PubMed articleLink to PubMed article]
    morphogenesis of an epithelium [IMPLink to PubMed article]
    positive regulation of growth rate [IMPLink to PubMed articleLink to PubMed article]
    embryonic development ending in birth or egg hatching [IMPLink to PubMed article]
    post-embryonic body morphogenesis [IMPLink to PubMed article]
    gamete generation [IMPLink to PubMed articleLink to PubMed articleLink to PubMed article]
    mRNA processing [IEALink to PubMed article]
    reproduction [IMPLink to PubMed articleLink to PubMed article]
    Molecular Function: nucleic acid binding [IEALink to PubMed article]
    RNA binding [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEMNVAAPAA AVAGAAAPQP ADAERAMDTM NFEALHGKPM RIMWSQRDPA MRRSGAGNIF  60
   61 IKNLDKVIDN KSIYDTFSLF GNILSCKVAI DEDGFSKGYG FVHFETEEAA QNAIQKVNGM 120
  121 LLAGKKVFVG KFQPRAQRNR ELGETAKQFT NVYVKNFGDH YNKETLEKLF AKFGNITSCE 180
  181 VMTVEGKSKG FGFVAFANPE EAETAVQALH DSTIEGTDLK LHVCRAQKKS ERHAELKKKH 240
  241 EQHKAERMQK YQGVNLYVKN LDETVDDDGL KKQFESYGNI TSAKVMTDEN GRSKGFGFVC 300
  301 FEKPEEATSA VTEMNSKMVC SKPLYVAIAQ RKEDRRAQLA SQYMQRLASM RMHGNVPGAA 360
  361 MYNPTQPGPG YYVANPMQQQ RNFAGGQQMV RPGGRWGMQN QYPVQNQYMM AQGPGVYQNR 420
  421 MGRPQNQQGG PRGPPQQYNQ VAQGGVRMQG PPRTQNPGVQ QQNVPRPPQQ QQQQRPAPTG 480
  481 PKAPPQPYQA YQQRPQGIVI GGQEPLTSAM LAAAAPQEQK QLLGERIYAL IEKLYPGHKD 540
  541 AGKITGMMLE IDNSELIMML QDSELFRSKV DEAASVLVSA QKQ

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run hcp-1 hcp1 IP from december2004 Cheeseman, I.M., et al. (2005)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..241] PSI-BLAST 42.30103 Poly(A)-binding protein
    2 View Details [242..346] FFAS03 5.1 No description for 2f3jA was found.
    3 View Details [347..517] PSI-BLAST 5.154902 Sec24
    4 View Details [518..583] PSI-BLAST 32.0 poly(A) binding protein

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • RNA binding
    		•  5.15097136329571 bayes_pls_golite062009
  • nucleic acid binding
    		•  4.92126426323641 bayes_pls_golite062009
  • mRNA binding
    		•  4.05281507540116 bayes_pls_golite062009
  • binding
    		•  3.64400841800969 bayes_pls_golite062009
    		• 2.60920363363072 bayes_pls_golite062009
  • transcription regulator activity
    		•  2.18211199677674 bayes_pls_golite062009
  • DNA binding
    		•  1.98418556946403 bayes_pls_golite062009
  • single-stranded RNA binding
    		•  1.46469774223879 bayes_pls_golite062009
  • poly-pyrimidine tract binding
    		•  1.36691748240059 bayes_pls_golite062009
  • protein binding
    		•  1.12215421354121 bayes_pls_golite062009
  • transcription factor activity
    		•  1.07843408116687 bayes_pls_golite062009
  • mRNA 3'-UTR binding
    		•  0.824614388276642 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  0.383589644462932 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.
    4 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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