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Protein Overview: cyh-1

General Information:
Name(s) found: cyh-1 / CE36037 [WormBase]
Description(s) found:
Found 18 descriptions.
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  • WBGene00021714 locus:cyh-1 status:Confirmed UniProt:Q9N4U0 protein_id:CCD64712.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 332 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: locomotory behavior [IMPLink to PubMed article]
    hermaphrodite genitalia development [IMPLink to PubMed article]
    morphogenesis of an epithelium [IMPLink to PubMed article]
    nematode larval development [IMPLink to PubMed article]
    embryonic development ending in birth or egg hatching [IMPLink to PubMed articleLink to PubMed articleLink to PubMed articleLink to PubMed article]
    positive regulation of growth rate [IMPLink to PubMed article]
    gamete generation [IMPLink to PubMed article]
    cell cycle [IEALink to PubMed article]
    positive regulation of multicellular organism growth [IMPLink to PubMed article]
    growth [IMPLink to PubMed article]
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MYATSTQKRE WTYTPEKLAA MRLEINIKFR QKYESVMQPD ELELFVTPEE ELRMQRSIED  60
   61 AALKFADKFR PHIWPSVKWT ALAFFKRAFL VWVPSDTSIR MVMMACFYLA MKIDEFYITI 120
  121 EDFVKNMNVG EPRQNAERIL KLEPELMKIL DYNLTVHCPY RPYEGHLMDM KTRMLLLNFD 180
  181 LESIRRDSMR FFQNALQTDV LLLYPPSQIA LAAINFGLHA QGKSDEILRE FLRKLIGIEE 240
  241 DSWAHRDARP EDLEKLEKTV TRVNQIMREV DRNFVAVTEQ ERENHKSQLA RIQALIPALD 300
  301 ERRKEQWLAG GGVGLMPGEL AEQPVDSDDE IN

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..332] PSI-BLAST 42.522879 CYCLIN H, A POSITIVE REGULATORY SUBUNIT OF CDK ACTIVATING KINASE

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • general RNA polymerase II transcription factor activity
    		•  8.12427628405368 bayes_pls_golite062009
  • transcription regulator activity
    		•  2.795846725429 bayes_pls_golite062009
  • binding
    		•  2.22200513900429 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  2.00665312545368 bayes_pls_golite062009
  • DNA binding
    		•  1.6980508926231 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.63159454080484 bayes_pls_golite062009
  • protein kinase regulator activity
    		•  1.57249948737107 bayes_pls_golite062009
  • kinase regulator activity
    		•  1.52575847462915 bayes_pls_golite062009
  • cyclin-dependent protein kinase regulator activity
    		•  1.46764878302741 bayes_pls_golite062009
  • protein binding
    		•  1.37124095423514 bayes_pls_golite062009
  • transcription factor activity
    		•  1.0145450763465 bayes_pls_golite062009
  • transcription factor binding
    		•  0.749278791251235 bayes_pls_golite062009
  • enzyme regulator activity
    		•  0.614716645534491 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.36347576272001 bayes_pls_golite062009
  • transcription coactivator activity
    		•  0.138191616709499 bayes_pls_golite062009
  • transcription activator activity
    		•  0.0696060248241566 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.87

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle