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Protein Overview: alp-1

General Information:
Name(s) found: alp-1 / CE35945 [WormBase]
Description(s) found:
Found 18 descriptions.
SHOW ALL
  • WBGene00001132 locus:alp-1 status:Confirmed UniProt:G5EEL1 protein_id:CAB54312.2 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 645 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: pharyngeal pumping [IMPLink to PubMed article]
    locomotory behavior [IMPLink to PubMed article]
    determination of adult lifespan [IMPLink to PubMed article]
    Molecular Function: zinc ion binding [IEALink to PubMed article]
    protein binding [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MERVTVRMAR SDRRTPWGFG VTEAPDGAVL IVNVIGGSLA DRAGLRNGDV VDRLEDLDNL  60
   61 DINAVDRLLV TAHEKIELIV TRQPSGAATR IWRPEVTENT GPGQDQTPYR VNLQHSSDTR 120
  121 PPQGFNNSAL PFETDQRVKH MQYNSPLGIY SDKSAAEQYV QQTQGLGDNS GARAAAQRQD 180
  181 EPAYLRSETL RLLKEQEHGS AGGAGTTLSN HPNPSGLPVC FMCTRPILGV MARAAGKNLH 240
  241 GDCLSCATCG NSLRNVGHHF IEDKFYCDIH GTQRKHGGRP GMDPNIFVKS SPTAAQPVHI 300
  301 QDSPRAAYHP QVNTARPVSV SPAPSAGSKT VTTHYHTPKT QGILSPGQRG VPTAAFGADL 360
  361 SKSVTYGGGV GPGGTHYDSN RLSPAPSQYS TQSRNQSQQH YQQHVVQAPP PVPSNPPPSN 420
  421 GSSYTKTSFE RTTTETRPQQ NTGAPRAGDF RGTGHLTTTT TTQQNGGRAP FCESCKQQIR 480
  481 GAFVLATGKS WCPEHFVCAN SSCRRRLLEC GFVEEDGQKF CESCFEQHIA PRCNKCSKPI 540
  541 ISDCLNALQK KWHPTCFTCA HCQKPFGNSA FYLEQGLPYC EQDWNALFTT KCVSCRYPIE 600
  601 AGDRWVEALG NAFHSNCFTC ARCNHNLEGE SFFAKNGQPF CRLHA

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..82] PSI-BLAST 15.0 No description for 2uzcA was found.
    2 View Details [83..146] deduced N/A No confident structure predictions are available.
    3 View Details [147..302] PSI-BLAST 15.69897 Transcription factor IIIA, TFIIIA
    4 View Details [303..508] PSI-BLAST 53.69897 No description for 2i13A was found.
    5 View Details [509..549] PSI-BLAST 8.0 Solution structures of the C2H2 type zinc finger domain of human Transcriptional repressor CTCF
    6 View Details [550..645] PSI-BLAST 15.0 Solution structures of the C2H2 type zinc finger domain of human Zinc finger protein 24

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3
    Term Confidence Notes
  • binding
    		•  2.90895627801407 bayes_pls_golite062009
  • DNA binding
    		•  2.69897474879997 bayes_pls_golite062009
  • transcription regulator activity
    		•  2.66654367524547 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.64459048886659 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  2.22104591928521 bayes_pls_golite062009
  • transcription factor activity
    		•  1.78340377434481 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  1.51308363851862 bayes_pls_golite062009
  • chromatin binding
    		•  1.04070653186107 bayes_pls_golite062009
  • transcription activator activity
    		•  0.91635578222038 bayes_pls_golite062009
  • protein binding
    		•  0.905022998164426 bayes_pls_golite062009
  • tubulin binding
    		•  0.744315484113484 bayes_pls_golite062009
  • microtubule binding
    		•  0.576452165256057 bayes_pls_golite062009
  • specific RNA polymerase II transcription factor activity
    		•  0.47431986827149 bayes_pls_golite062009
  • transcription repressor activity
    		•  0.394719390279559 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  0.27893970640609 bayes_pls_golite062009
  • transcription factor binding
    		•  0.26289228626913 bayes_pls_golite062009
  • signal transducer activity
    		•  0.0590340677124848 bayes_pls_golite062009
  • molecular transducer activity
    		•  0.0590340677124848 bayes_pls_golite062009
    4 No functions predicted.
    5
    Term Confidence Notes
  • binding
    		•  2.90895627801407 bayes_pls_golite062009
  • DNA binding
    		•  2.69897474879997 bayes_pls_golite062009
  • transcription regulator activity
    		•  2.66654367524547 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.64459048886659 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  2.22104591928521 bayes_pls_golite062009
  • transcription factor activity
    		•  1.78340377434481 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  1.51308363851862 bayes_pls_golite062009
  • chromatin binding
    		•  1.04070653186107 bayes_pls_golite062009
  • transcription activator activity
    		•  0.91635578222038 bayes_pls_golite062009
  • protein binding
    		•  0.905022998164426 bayes_pls_golite062009
  • tubulin binding
    		•  0.744315484113484 bayes_pls_golite062009
  • microtubule binding
    		•  0.576452165256057 bayes_pls_golite062009
  • specific RNA polymerase II transcription factor activity
    		•  0.47431986827149 bayes_pls_golite062009
  • transcription repressor activity
    		•  0.394719390279559 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  0.27893970640609 bayes_pls_golite062009
  • transcription factor binding
    		•  0.26289228626913 bayes_pls_golite062009
  • signal transducer activity
    		•  0.0590340677124848 bayes_pls_golite062009
  • molecular transducer activity
    		•  0.0590340677124848 bayes_pls_golite062009
    6
    Term Confidence Notes
  • binding
    		•  2.90895627801407 bayes_pls_golite062009
  • DNA binding
    		•  2.69897474879997 bayes_pls_golite062009
  • transcription regulator activity
    		•  2.66654367524547 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.64459048886659 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  2.22104591928521 bayes_pls_golite062009
  • transcription factor activity
    		•  1.78340377434481 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  1.51308363851862 bayes_pls_golite062009
  • chromatin binding
    		•  1.04070653186107 bayes_pls_golite062009
  • transcription activator activity
    		•  0.91635578222038 bayes_pls_golite062009
  • protein binding
    		•  0.905022998164426 bayes_pls_golite062009
  • tubulin binding
    		•  0.744315484113484 bayes_pls_golite062009
  • microtubule binding
    		•  0.576452165256057 bayes_pls_golite062009
  • specific RNA polymerase II transcription factor activity
    		•  0.47431986827149 bayes_pls_golite062009
  • transcription repressor activity
    		•  0.394719390279559 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  0.27893970640609 bayes_pls_golite062009
  • transcription factor binding
    		•  0.26289228626913 bayes_pls_golite062009
  • signal transducer activity
    		•  0.0590340677124848 bayes_pls_golite062009
  • molecular transducer activity
    		•  0.0590340677124848 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.83

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle