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Protein Overview: CE35438

General Information:
Name(s) found: CE35438 [WormBase]
Description(s) found:
Found 15 descriptions.
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  • WBGene00016896 locus:nep-4 status:Partially_confirmed UniProt:O45311 protein_id:CCD67890.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 437 amino acids

    Gene Ontology:
    Cellular Component: membrane [IEALink to PubMed article]
    Biological Process: proteolysis [IEALink to PubMed article]
    Molecular Function: neprilysin activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MWLIILFCFL PTQNAYEHPF DFIENALEKI VDWKSDPCDD FYRHACPVGS IEDIIKVSMQ  60
   61 PLKDALNHSW KQKGQRNEGK VYNINFRRSH ICCHFFCKLL FIYYDYQYRF INYVTFYDGM 120
  121 LQPLYYHVEA NVTDGINEIH QMMEDMVELG NIWLEKTPWV INNNLTEEMK NITNAIKMPV 180
  181 SLTKYTNFIY NLLSPIETDF LNCVSEFEGI QNNTLFCLFY SAKIFVRTRG SYFIDDNGYN 240
  241 AEGTIYFGFP NYYHTTYGNW RASKLGYTGT RVGHEIGHTF IEHSINPDGL PYFSKPAEDC 300
  301 VQNQYLKTCN EYYEGEVPDA CNTSDYTFDD NGADVFGLQL AYAILERDLS DQLREQADGL 360
  361 KITNEQLLFY SFAYRFCRGS KSNTTDGSHS HHNVRINAVA QMPGFQQAFN CASDSRMMKS 420
  421 ATKQCVIYGN NAPETRK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..437] PSI-BLAST 100.0 Neutral endopeptidase (neprilysin)

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • catalytic activity
    		•  0.361128926739778 bayes_pls_golite062009
  • hydrolase activity
    		•  0.29183147920977 bayes_pls_golite062009
  • peptidase activity
    		•  0.23695590197447 bayes_pls_golite062009
  • peptidase activity, acting on L-amino acid peptides
    		•  0.0341081586881899 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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