Protein Overview: tir-1

General Information:
Name(s) found:	tir-1 / CE33995 [WormBase]
Description(s) found: Found 19 descriptions. SHOW ALL	WBGene00006575 locus:tir-1 Sterile alpha and TIR motif-containing protein tir-1 status:Partially_confirmed UniProt:Q86DA5 protein_id:CAD90174.1 [WormBase]
Organism:	Caenorhabditis elegans
Length:	1000 amino acids
Gene Ontology:
Cellular Component:	membrane [IEA]
Biological Process:	signal transduction [IEA] positive regulation of growth rate [IMP] embryonic development ending in birth or egg hatching [IMP] protein localization [IMP] cell-cell signaling involved in cell fate commitment [IMP] defense response [IMP] receptor-mediated endocytosis [IMP] defense response to bacterium [IMP] growth [IMP] reproduction [IMP] activation of MAPK activity [IMP] nematode larval development [IMP] innate immune response [IEA][IEP] defense response to fungus [IEP][IMP]
Molecular Function:	transmembrane receptor activity [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLPNRKPPRP SPSFQSLNNN NQRFPLRRSL KIAQAHSLPT VPSEDAKDDD LITPELSTDF  60
   61 DFREIQHRYL MALQNEQDGE TTSTDDAFFE LDDDDDLSSP SVPGSPVDPP SISVPLPPKS 120
  121 APPCPTQPAP LTNGDLYPTI LSNGTPIPNG RITPALSTVS VSLIHEARLQ QSLSTPCNGS 180
  181 EEEMHNGQVR KESEYRRFKS EGSTAGASLP AAEKTHMDEL SPVDQRSTSG TARFLIQQDS 240
  241 VVNPSTKMSN TEQVAMMHTL KTKLSKYQAM MDKAFEEIAK VEDANIIEGC TIVRKLMRKV 300
  301 WNTPKVSADL ANALCDYLRD RDYFDKLIKM FISPNTAACD QVRMECGKVL EECTSSANLE 360
  361 YIVNKSYTKK IMIVAMKLNK TPDQQRLSLS LIGNLFKHSN AVSLSLIETD VIDHIILTFK 420
  421 RAPECPDILR HAALALANIL LYTCFEGKKK IIQKKIPEWL FFLASQADDV TRYYACIAVC 480
  481 TIVSVKEFEP LVRKSDTMKL VEPFLQVHDP ATFARDYHKY AQGNTKEWLE RLLPMLQPSR 540
  541 RREARSVAAF HFTLEATIKK EQNKLDVFQE IGAIQALKEV ASSPDEVAAK FASEALTVIG 600
  601 EEVPYKLAQQ VPGWTCADVQ YWVKKIGFEE YVEKFAKQMV DGDLLLQLTE NDLKHDVGMI 660
  661 SGLHRKRFLR ELQTLKVAAD YSSVDESNLD NFLMGLSPEL SVYTYQMLTN GVNRSLLSSL 720
  721 TDEMMQNACG ITNPIHRLKL TQAFETAKHP DDVEVAMLSK QIDVFISYRR STGNQLASLI 780
  781 KVLLQLRGYR VFIDVDKLYA GKFDSSLLKN IQAAKHFILV LTPNSLDRLL NDDNCEDWVH 840
  841 KELKCAFEHQ KNIIPIFDTA FEFPTKEDQI PNDIRMITKY NGVKWVHDYQ DACMAKVVRF 900
  901 ITGELNRTTP TTKEMPSISR KTTQQRWQTT NTVSRTGPSR SIGGPRMEPP TPTCKLLKHR 960
  961 HLVYYLIFLV FSVTPTGSQE RATSTRRKIQ PSASTTSDRN

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

The following runs contain data for this protein:

	BAIT	COMMENTS	PUBLICATION
View Run	hcp-1	hcp1 IP from december2004	Cheeseman, I.M., et al. (2005)

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.85

Protein Overview: tir-1

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: