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Protein Overview: unc-62

General Information:
Name(s) found: unc-62 / CE33585 [WormBase]
Description(s) found:
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  • WBGene00006796 locus:unc-62 Homeobox protein unc-62 status:Confirmed UniProt:Q9N5D6 protein_id:CCD72266.1 [WormBase]
  • gi|72000786|ref|NP_001024174.1| UNCoordinated family member (unc-62) [Caenorhabditis elegans] [NCBI NR]
  • gi|28894814|gb|AAO61421.1| Uncoordinated protein 62, isoform f [Caenorhabditis elegans] [NCBI NR]
  • ref|NP_504233.2| C.Elegans Homeobox, UNCoordinated locomotion UNC-62, LEThal LET-328, kNOB-like posterior, NO Backside NOB-5 (60.3 kD) (unc-62) [Caenorhabditis elegans] [NCBI NR]
  • gi|18182381|gb|AAL65142.1|AF427474_1 UNC-62 splice variant 1a-7a [Caenorhabditis elegans] [NCBI NR]
  • [wormpep104.fasta]
  • CE33585 WBGene00006796 locus:unc-62 status:Confirmed TR:Q8WRQ6 protein_id:AAO61421.1 [wormpep150.fasta]
  • 33585 WBGene00006796 locus:unc-62 status:Confirmed TR:Q8WRQ6 protein_id:AAO61421.1 [wormpep130-phg-ecoli-orf-rand.fasta]
  • C.Elegans Homeobox, UNCoordinated locomotion UNC-62, LEThal LET-328, kNOB-like posterior, NO Backside NOB-5 (60.3 kD) (unc-62) [Caenorhabditis elegans]gi|28894814|gb|AAO61421.1| Uncoordinated protein 62, isoform f [Caenorhabditis elegans]gi|18182381|gb| [nrdb_11152004_Chlamydomonas]
  • locus:unc-62 status:Confirmed TR:Q8WRQ6 protein_id:AAO61421.1 [wormpep115.fasta.reversed]
  • CE33585 WBGene00006796 locus:unc-62 status:Confirmed UniProt:UNC62_CAEEL protein_id:AAO61421.1 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta]
  • CE33585 WBGene00006796 locus:unc-62 status:Confirmed UniProt:Q8WRQ6_CAEEL protein_id:AAO61421.1| [wormORF-contam.fasta]
  • UNCoordinated family member (unc-62) [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • UNC-62 splice variant 1a-7a [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • Uncoordinated protein 62, isoform f [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • CE33585 WBGene00006796 locus:unc-62 status:Confirmed UniProt:Q9N5D6 protein_id:AAO61421.1 [wormbase_c-elegans_2.11_01-10-2010_reversed.fasta]
  • [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr]
  • CE33585 WBGene00006796 locus:unc-62 status:Confirmed UniProt:Q9N5D6 protein_id:CCD72266.1 [wormbase_c_elegans_ws231_03-13-2012_reversed.fasta]
  • CE33585 WBGene00006796 locus:unc-62 status:Confirmed UniProt:Q9N5D6 protein_id:CCD72266.1 Homeobox protein unc-62 [wormpep246-ecoli-contam.fasta]
  • Isoform of Q9N5D6, Isoform f of Homeobox protein unc-62 OS=Caenorhabditis elegans GN=unc-62 [CAEEL.fasta.20160308]
    • Organism: Caenorhabditis elegans
    Length: 560 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IEALink to PubMed article]
    Biological Process: oocyte construction [IMPLink to PubMed article]
    locomotory behavior [IMPLink to PubMed articleLink to PubMed article]
    hermaphrodite genitalia development [IMPLink to PubMed article]
    embryonic development ending in birth or egg hatching [IMPLink to PubMed articleLink to PubMed articleLink to PubMed article]
    regulation of transcription, DNA-dependent [IEALink to PubMed article]
    oviposition [IMPLink to PubMed articleLink to PubMed article]
    cell migration [IMPLink to PubMed article]
    positive regulation of multicellular organism growth [IMPLink to PubMed article]
    Molecular Function: transcription factor activity [IEALink to PubMed article]
    sequence-specific DNA binding [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSGDSKVWAH ASADTWAVQN GISTYDLDTS SIKREKRDHN EQFNDGYGPP PGSASADPAS  60
   61 YIADPAAFYN LYTNMGGAPT STPMMHHEMG EAMKRDKESI YAHPLYPLLV LLFEKCELAT 120
  121 STPRDTSRDG STSSDVCSSA SFKDDLNEFV RHTQENADKQ YYVPNPQLDQ IMLQSIQMLR 180
  181 FHLLELEKVH ELCDNFCNRY VVCLKGKMPL DIVGDERASS SQPPMSPGSM GHLGHSSSPS 240
  241 MAGGATPMHY PPPYEPQSVP LPENAGVMGG HPMEGSSMAY SMAGMAAAAA SSSSSSNQAG 300
  301 DHPLANGGTL HSTAGASQTL LPIAVSSPST CSSGGLRQDS TPLSGETPMG HANGNSMDSI 360
  361 SEAAPSSASS SSSSKNKPST PNGGRIGKSR GRGIFPKQAT NRLRQWLFQN LTHPYPSEEQ 420
  421 KKQLAKETGL TILQVNNWFI NARRRIVQPM IDQNNRAGRS GQMNVCKNRR RNRSEQSPGP 480
  481 SPDSGSDSGA NYSPDPSSLA ASTAMPYPAE FYMQRTMPYG GFPSFTNPAM PFMNPMMGFQ 540
  541 VAPTVDALSQ QWVDLSAPHE

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..228] MSA 6.182974 View MSA. No confident structure predictions are available.
    2 View Details [229..352] deduced N/A No confident structure predictions are available.
    3 View Details [353..467] PSI-BLAST 15.69897 pbx1
    4 View Details [468..560] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3
    Term Confidence Notes
  • transcription regulator activity
    		•  1.62959077995642 bayes_pls_golite062009
  • binding
    		•  1.48969201384255 bayes_pls_golite062009
  • DNA binding
    		•  1.2137926921894 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.02805703044131 bayes_pls_golite062009
  • transcription factor activity
    		•  0.89626527070971 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  0.06790788268651 bayes_pls_golite062009
  • protein binding
    		•  0.012115247005138 bayes_pls_golite062009
    4 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.95

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle